CRISPR Therapeutics AG (CRSP) Ownership

NASDAQ: CRSPTop holders, insider trades and short interest.

CRSP ownership summary

as of October 18, 2026
Institutions
78.3%
of shares outstanding
Insiders
5.90%
of shares outstanding
Shares outstanding
96.7M
Float
96.2M
shares available to trade
Short interest
22.12%
18.7M shares short
Days to cover
11.76
short interest down 2.1% vs prior month
  • Institutions 78.27%
  • Insiders 5.90%
  • Other investors 15.84%

CRSP top institutional holders

20 largest
CRISPR Therapeutics AG top institutional holders
#Holder% of sharesSharesValueChangeReported
1ARK Investment Management LLC9.78%9.5M$466.0M−1.9M (−16.4%)June 30, 2026
2BlackRock Inc8.63%8.3M$411.2M+668,904 (+8.7%)June 30, 2026
3Orbis Allan Gray Ltd5.64%5.4M$268.4M−656,850 (−10.8%)June 30, 2026
4Capital World Investors4.91%4.7M$233.9M+24,488 (+0.5%)June 30, 2026
5State Street Corp4.47%4.3M$212.8M+339,166 (+8.5%)June 30, 2026
6GSK PLC3.33%3.2M$158.6M—June 30, 2026
7Geode Capital Management, LLC2.60%2.5M$123.6M+132,751 (+5.6%)June 30, 2026
8T. Rowe Price Investment Management,Inc.2.12%2.1M$101.1M−899,578 (−30.5%)June 30, 2026
9SR ONE CAPITAL MANAGEMENT, LP2.11%2.0M$100.4M—June 30, 2026
10Two Sigma Investments LLC2.06%2.0M$97.9M+505,570 (+34.1%)June 30, 2026
11FMR Inc1.97%1.9M$94.0M−46,191 (−2.4%)June 30, 2026
12Sumitomo Mitsui Trust Group Inc1.78%1.7M$84.7M−133,141 (−7.2%)June 30, 2026
13Amova Asset Management Americas, Inc1.78%1.7M$84.7M−133,778 (−7.2%)June 30, 2026
14EcoR1 Capital, LLC1.44%1.4M$68.4M—June 30, 2026
15UBS Group AG1.36%1.3M$64.9M−445,031 (−25.2%)June 30, 2026
16Capital Research & Mgmt Co - Division 31.31%1.3M$62.5M+81,613 (+6.9%)June 30, 2026
17Vanguard Capital Management, LLC1.22%1.2M$58.2M+39,304 (+3.4%)June 30, 2026
18Bank of America Corp1.19%1.2M$56.9M+172,033 (+17.5%)June 30, 2026
19NEA Management Company, LLC1.09%1.1M$52.1M—June 30, 2026
20Charles Schwab Investment Management Inc1.09%1.1M$52.1M+18,488 (+1.8%)June 30, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 9 holders added 2.0M shares and 7 cut 4.2M.

CRSP top mutual fund and ETF holders

20 largest
CRISPR Therapeutics AG top fund holders
#Holder% of sharesSharesValueChangeReported
1ARK Innovation ETF6.60%6.4M$314.1M−498,871 (−7.3%)September 30, 2026
2State Street® SPDR® S&P® Biotech ETF2.83%2.7M$134.7M−52,050 (−1.9%)September 30, 2026
3iShares Russell 2000 ETF2.41%2.3M$114.5M−26,816 (−1.1%)September 30, 2026
4ARK Genomic Revolution ETF2.18%2.1M$103.6M+5,142 (+0.2%)September 30, 2026
5American Funds New Perspective A2.01%1.9M$95.7M—September 30, 2026
6American Funds SMALLCAP World A1.75%1.7M$83.4M—September 30, 2026
7American Funds Growth Fd of Amer A1.46%1.4M$69.6M—September 30, 2026
8Orbis Global Equity Investor1.27%1.2M$60.6M—June 30, 2026
9Fidelity Small Cap Index1.05%1.0M$50.2M+8,486 (+0.8%)July 31, 2026
10Amova ARK Disruptive Innovation A USD0.91%879K$43.3M−63,332 (−6.7%)August 31, 2026
11T. Rowe Price Mid-Cap Growth0.89%858K$42.3M−191,100 (−18.2%)September 30, 2026
12Orbis SICAV Global Bal Instl Inv0.87%838K$41.3M+19,622 (+2.4%)March 31, 2026
13iShares Russell 2000 Value ETF0.76%731K$36.0M+1,108 (+0.2%)September 30, 2026
14iShares Biotechnology ETF0.72%700K$34.5M−5,304 (−0.8%)September 30, 2026
15Fidelity Growth Company Fund0.61%592K$29.2M—August 31, 2026
16Vanguard Russell 2000 ETF0.54%523K$25.7M−13,200 (−2.5%)September 30, 2026
17Amova ARK Pstv Chg Innovt P JPY Acc0.53%509K$25.1M−24,747 (−4.6%)August 31, 2026
18Schwab US Small-Cap ETF™0.53%509K$25.1M+342 (+0.1%)September 30, 2026
19Fidelity Extended Market Index0.49%473K$23.3M−6,548 (−1.4%)August 31, 2026
20Orbis Optimal (US$) Fund0.40%384K$18.9M+41,175 (+12.0%)March 31, 2026

Funds report holdings monthly or quarterly; dates differ by fund.

CRSP insider transactions

latest 16
CRISPR Therapeutics AG insider transactions
DateNameTransactionPriceSharesValue
2026-03-23James R KasingerSell$46.783,182$148,854
2026-03-23Samarth KulkarniSell$46.7810,020$468,736
2026-03-16James R KasingerSell$48.263,450$166,497
2026-03-16Naimish PatelSell$48.263,150$152,019
2026-03-16Samarth KulkarniSell$48.2610,349$499,443
2026-03-11James R KasingerSell$52.802,800$147,840
2026-03-11Samarth KulkarniSell$52.809,798$517,334
2026-02-19James R KasingerSell$52.582,112$111,049
2026-02-19Samarth KulkarniSell$52.586,967$366,325
2026-01-22Samarth KulkarniSell$60.2360,000$3.6M
2026-01-20Samarth KulkarniSell$51.7530,000$1.6M
2025-10-17Samarth KulkarniSell$67.9150,895$3.5M
2025-10-14James R KasingerSell$66.601,076$71,662
2025-10-14Samarth KulkarniSell$66.604,242$282,517
2025-07-16Simeon GeorgeBuy$52.03989,812$51.5M
2025-05-29Naimish PatelSell$35.943,932$141,316

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

CRSP shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns CRSP

Institutional investors own 78.3% of CRISPR Therapeutics's shares and insiders 5.90%. The largest holder is ARK Investment Management LLC with 9.78% of the shares (9.5M), as of June 30, 2026. Among the top 20 institutions, 9 added shares and 7 reduced their stake in the latest filings. Short interest is 22.12% of the float, or 11.76 days of average trading volume. The share count rose 2,148.1% since 2014.

Related: CRSP analyst forecast, CRSP key metrics. See the CRSP stock overview for the latest quote and news.

CRSP ownership FAQ

Who owns the most CRISPR Therapeutics stock?

The largest shareholders of CRISPR Therapeutics are ARK Investment Management LLC (9.78%), BlackRock Inc (8.63%), Orbis Allan Gray Ltd (5.64%), Capital World Investors (4.91%), State Street Corp (4.47%).

What percentage of CRISPR Therapeutics is owned by institutions?

Institutions hold 78.3% of CRISPR Therapeutics's shares outstanding; insiders hold 5.90%.

Which funds own CRISPR Therapeutics?

The largest fund holders of CRISPR Therapeutics are ARK Innovation ETF (6.60%), State Street® SPDR® S&P® Biotech ETF (2.83%), iShares Russell 2000 ETF (2.41%), ARK Genomic Revolution ETF (2.18%), American Funds New Perspective A (2.01%).

What is CRISPR Therapeutics's short interest?

18.7M shares of CRISPR Therapeutics were sold short, 22.12% of the float; at the average daily volume it would take 11.76 days to cover.

Are insiders buying or selling CRISPR Therapeutics?

Of the latest 16 reported insider transactions in CRISPR Therapeutics (since May 29, 2025), 1 were purchases and 15 were sales.

How many shares of CRISPR Therapeutics are outstanding?

CRISPR Therapeutics has 96.7M shares outstanding, of which 96.2M are in the public float.

Biotechnology: ownership