Cellectis S.A. (CLLS) Key Metrics

NASDAQ: CLLSValuation, returns, debt and efficiency ratios over 10 years.

CLLS valuation today

Trailing 12 months · as of October 17, 2026
Market cap
$104.8M
Enterprise value
$78.3M
P/E (TTM)
—
Forward P/E
—
PEG ratio
—
Price / sales
1.6
10-yr median 14.9
Price / book
3.9
10-yr median 2.1
EV / EBITDA
—
Dividend yield
—
Beta
2.91

CLLS key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

CLLS valuation Price multiples at each fiscal year-end price.

Price / sales+69.4%
6.7
2025 · hover or tap a bar for each year
2016: 14.3 (−26.8%)2017: 41.3 (+189.8%)2018: 53.3 (+29.1%)2019: 47.8 (−10.3%)2020: 15.6 (−67.5%)2021: 4.7 (−70.0%)2022: 5.0 (+7.1%)2023: 232.6 (+4,561.0%)2024: 3.9 (−98.3%)2025: 6.7 (+69.4%)
20162025
Price / book+414.0%
6.4
2025 · hover or tap a bar for each year
2016: 2.2 (−40.4%)2017: 3.9 (+76.1%)2018: 1.7 (−57.5%)2019: 2.3 (+39.0%)2020: 4.1 (+75.8%)2021: 1.6 (−61.6%)2022: 0.8 (−47.9%)2023: 2.1 (+155.7%)2024: 1.2 (−40.0%)2025: 6.4 (+414.0%)
20162025
Free cash flow yield−20.7 pts
−8.8%
2025 · hover or tap a bar for each year
2016: −7.3% (−7.3 pts)2017: −5.3% (+2.0 pts)2018: −10.8% (−5.5 pts)2019: −11.3% (−0.5 pts)2020: −10.8% (+0.5 pts)2021: −35.7% (−24.9 pts)2022: −94.0% (−58.2 pts)2023: −14.7% (+79.3 pts)2024: 12.0% (+26.7 pts)2025: −8.8% (−20.7 pts)
20162025

CLLS valuation history

Fiscal year-endToday10-year median

CLLS returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

CLLS debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

CLLS cash returned to shareholders

DividendsBuybacksFree cash flow

CLLS price vs earnings per share

Share price at year-endEPS (right axis)

CLLS key metrics

2016–2025
Cellectis S.A. key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$485.4M$163.0M$175.6M$95.7M$344.7M$1.15B$726.6M$678.9M$1.04B$607.0M
Enterprise value$396.6M−$5.8M$56.8M$73.7M$259.4M$988.6M$413.3M$228.4M$743.4M$318.3M
Price / sales6.73.9232.65.04.715.647.853.341.314.3
Price / book6.41.22.10.81.64.12.31.73.92.2
Price / free cash flow—8.3————————
Price / operating cash flow—7.4————————
EV / sales5.4-0.175.33.83.513.427.217.929.57.5
Earnings yield−13.9%−22.6%−57.6%−103.2%−25.0%−6.3%−12.5%−11.6%−9.6%−10.5%
Free cash flow yield−8.8%12.0%−14.7%−94.0%−35.7%−10.8%−11.3%−10.8%−5.3%−7.3%
Dividend yield0.0%0.0%0.0%0.6%0.0%0.0%————
Shareholder yield (dividends + buybacks)0.0%0.0%0.3%1.2%0.0%0.0%0.1%0.0%0.0%0.0%
Share price at fiscal year-end$4.84$1.80$3.08$2.10$8.12$27.06$17.12$16.65$29.15$16.95
Per share
Revenue per share$0.73$0.46$0.01$0.42$1.74$1.74$0.36$0.31$0.71$1.19
Earnings per share−$0.67−$0.41−$1.77−$2.17−$2.03−$1.71−$2.14−$1.93−$2.78−$1.78
Operating cash flow per share−$0.40$0.24−$0.43−$1.92−$2.46−$1.89−$1.63−$1.67−$1.47−$0.87
Free cash flow per share−$0.42$0.22−$0.45−$1.97−$2.90−$2.93−$1.93−$1.79−$1.54−$1.24
Cash per share$2.08$2.87$3.57$2.14$4.39$6.31$8.50$11.08$8.32$8.11
Book value per share$0.76$1.45$1.49$2.59$5.21$6.68$7.42$10.04$7.48$7.65
Tangible book value per share$0.75$1.43$1.47$2.57$5.17$6.64$7.40$10.01$7.44$7.61
Dividends per share$0.00$0.00$0.00$0.01$0.00$0.00————
Capex per share$0.02$0.03$0.02$0.05$0.44$1.05$0.31$0.12$0.07$0.37
Debt per share$1.20$1.01$1.49$1.66$2.38$2.51$1.12$0.03$0.00$0.05
Shares outstanding100.3M90.6M57.0M45.6M42.4M42.5M42.4M40.8M35.7M35.8M
Change in shares outstanding+10.7%+58.9%+25.2%+7.3%−0.1%+0.1%+4.1%+14.2%−0.3%+3.7%
Returns & profitability
Return on equity (ROE)−65.3%−34.1%−99.7%−58.2%−34.2%−24.2%−25.0%−23.3%−36.7%−22.7%
Return on invested capital (ROIC)———−61.0%−52.3%−108.8%————
Return on assets (ROA)−19.1%−10.2%−33.9%−30.7%−20.3%−15.5%−18.7%−18.9%−29.9%−18.2%
Return on tangible assets−20.9%−9.6%−30.3%−37.9%−22.7%−15.5%−19.4%−15.8%−30.0%−19.4%
Free cash flow margin−58.3%47.0%—−468.9%−166.5%−168.6%−540.5%−573.6%−218.3%−104.3%
Financial health
Total debt$119.9M$91.5M$85.1M$75.8M$100.9M$106.7M$47.6M$1.4M$34,000$1.8M
Cash & short-term investments$208.7M$260.3M$203.8M$97.7M$186.1M$268.2M$360.9M$451.9M$297.0M$290.5M
Net debt−$88.8M−$168.8M−$118.8M−$21.9M−$85.3M−$161.6M−$313.3M−$450.5M−$296.9M−$288.7M
Debt / equity1.580.701.000.640.460.380.150.000.000.01
Debt / assets0.370.240.250.290.260.230.100.000.000.01
Current ratio1.621.731.502.284.576.066.2510.407.425.56
Quick ratio1.621.731.501.944.576.036.2110.407.425.56
Interest coverage-4.1-8.0-18.3-23.7-16.0-7.1-47.4—-165.4—
Working capital$90.5M$120.8M$77.9M$80.8M$176.1M$263.3M$328.9M$440.8M$279.7M$255.7M
Invested capital−$12.9M−$37.8M−$34.1M$96.0M$136.0M$122.2M$1.8M−$41.2M−$30.2M−$14.7M
Tangible asset value$75.4M$129.9M$84.0M$125.2M$234.6M$307.3M$354.4M$449.0M$284.5M$272.7M
Net current asset value−$12.6M$34.6M−$16.6M$8.5M$79.8M$154.7M$279.5M$437.1M$276.2M$255.2M
Graham net-net per share−$0.21$0.28−$0.50−$0.30$1.50$2.89$6.17$10.25$7.10$6.79
Capital allocation
Dividends paid$0$0$0$569,000$0$0————
Share buybacks (net)——$569,000$569,000——$469,000$0$0$137,000
Dividends + buybacks / free cash flow—0.0%————————
Capex / revenue3.2%6.2%142.1%12.7%25.1%60.1%85.3%38.4%10.5%31.3%
Capex / operating cash flow—11.7%————————
Capex / depreciation0.120.130.060.131.315.671.882.060.796.03
Stock-based compensation / revenue8.4%7.6%693.1%31.5%15.5%13.6%177.0%292.3%200.2%130.8%
R&D / revenue128.2%218.1%11,608.7%508.6%117.6%117.6%605.9%601.4%314.5%175.1%
SG&A / revenue11.8%20.3%1,075.4%91.3%51.2%59.8%283.2%371.1%177.7%96.9%
Efficiency
Days sales outstanding121.0203.09,839.0463.1124.185.1448.9381.8122.4123.7
Days of inventory on hand——535.52,241.9—22.750.835.025.631.4
Days payables outstanding669.5750.0996.94,657.0243.4271.0723.31,688.61,334.61,830.2
Cash conversion cycle (days)-548.5-547.09,377.7-1,952.0-111.2-163.3-223.6-1,271.9-1,186.6-1,675.0
Receivables turnover3.021.800.040.792.944.290.810.962.982.95
Payables turnover0.550.490.370.081.501.350.500.220.270.20
Inventory turnover——0.680.16—16.117.1810.4314.2511.62
Asset turnover0.210.120.000.060.170.160.030.030.080.12
Average receivables$24.2M$23.1M$20.4M$24.3M$25.1M$17.2M$18.7M$13.3M$8.4M$14.4M
Average payables$18.0M$18.9M$20.3M$22.6M$24.2M$26.9M$22.6M$12.7M$9.6M$8.5M
Average inventory——$10.9M$10.9M$803,000$2.3M$1.6M$262,500$183,895$145,266
Intangibles / total assets0.2%0.3%0.2%0.3%0.5%0.3%0.2%0.3%0.4%0.4%

Computed from CLLS's annual financial statements (latest annual report filed March 20, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

CLLS valuation and financial ratios

Cellectis earned a return on equity of −65.3% in fiscal 2025. It ended the year with $119.9 million of debt and $208.7 million in cash and short-term investments, a net cash position of $88.8 million. The share count rose 180.0% from 35.8M to 100.3M over 9 years.

See the CLLS income statement, the CLLS chart for price history, or the CLLS stock overview for the latest quote and news.

CLLS key metrics FAQ

What is Cellectis's return on equity?

Cellectis's return on equity (ROE) was −65.3% in fiscal 2025: net income of -$67.6 million on average shareholders' equity of $103.5 million.

How much debt does Cellectis have?

Cellectis had total debt of $119.9 million at the end of fiscal 2025, a debt-to-equity ratio of 1.58 and more cash than debt.

Does Cellectis pay a dividend?

Cellectis did not pay a dividend in fiscal 2025.

What is Cellectis's free cash flow yield?

Cellectis generated -$42.5 million of free cash flow in fiscal 2025, a free cash flow yield of −8.8% on its market value at year-end ($485.4 million).

What is Cellectis's current ratio?

Cellectis's current ratio was 1.62 at the end of fiscal 2025: current assets were 1.62 times current liabilities.

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