Cellectis S.A. (CLLS) Cash Flow Statement

NASDAQ: CLLSOperating cash, capex, free cash flow and buybacks.

Where CLLS’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$40.1M
−281.6% vs 2024
Capital expenditures
$2.4M
3.2% of revenue
Free cash flow
−$42.5M
−58.3% margin
Returned to shareholders
—
Change in cash
−$79.7M
cash at year-end $63.6M
Drawn from cash: $79.7MDrawn from cash$79.7MCurrency & other: $6.2MCurrency & other$6.2MCash used in operations: $40.1MCash used in operations$40.1M · 47%Investments (net): $25.9MInvestments (net)$25.9M · 30%Debt repayment: $16.2MDebt repayment$16.2M · 19%Capital expenditures, Acquisitions & other: $3.6MOther uses$3.6M · 4%$85.9M
Cash from operations
−$40.1M
Capital expenditures
−$2.4M
Investments (net)
−$25.9M
Acquisitions & other
−$1.3M
Net borrowing (repayment)
−$16.2M
Currency & other
+$6.2M
Change in cash
−$79.7M

Drawn to scale: where the cash came from and how it was used. Hover for values.

CLLS operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

CLLS cash flow trends, 2016–2025

Cellectis S.A. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$31.1M2016−$40.1M2025—
Capital expenditures$13.3M2016$2.4M2025−17.5%/yr
Free cash flow−$44.4M2016−$42.5M2025—
Free cash flow margin−104.3%2016−58.3%2025+46.1 pts
Stock-based compensation$55.7M2016$6.1M2025−21.8%/yr
Dividends paid$02020$02025—
Share buybacks (net)$137,0002016$569,0002023+22.6%/yr
Capex / revenue31.3%20163.2%2025−28.1 pts

Change is the average annual growth (CAGR) or the difference between the first and latest year.

CLLS cash flow by activity

OperatingInvestingFinancingChange in cash

CLLS net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

CLLS cash flow statement

Cellectis S.A. annual cash flow statement
2025202420232022202120202019201820172016
Operating activities
Net income−$67.8M−$36.7M−$116.8M−$98.7M−$96.7M−$53.6M−$115.2M−$88.3M−$103.7M−$63.9M
Depreciation & amortization$20.1M$19.8M$18.5M$18.4M$14.2M$7.8M$6.9M$2.4M$3.4M$2.2M
Stock-based compensation$6.1M$3.2M$5.2M$6.0M$11.5M$10.0M$26.9M$37.2M$50.4M$55.7M
Change in working capital−$41.7M$53.6M−$4.0M−$5.7M−$12.3M−$17.3M$11.7M−$9.1M−$17.8M−$24.9M
Other non-cash items$43.2M−$17.8M$72.3M−$7.5M−$21.2M−$27.2M$661,000−$10.3M$15.4M−$189,629
Cash from operating activities−$40.1M$22.1M−$24.7M−$87.4M−$104.6M−$80.3M−$69.1M−$68.1M−$52.3M−$31.1M
Investing activities
Capital expenditures−$2.4M−$2.6M−$1.1M−$2.4M−$18.6M−$44.4M−$13.0M−$4.9M−$2.7M−$13.3M
Investments (net)−$25.9M−$102.8M−$15.5M−$2.8M$27.0M−$54.3M−$35.9M$35.6M$1.8M−$50.5M
Acquisitions & other investing−$1.3M$2.8M$1.1M$2.4M−$1.2M$44.4M$13.0M$4.9M$2.7M$13.3M
Cash from investing activities−$29.6M−$102.6M−$15.5M−$2.8M$7.3M−$54.3M−$35.9M$35.6M$1.8M−$50.5M
Financing activities
Dividends paid$0$0$0−$569,000$0$0————
Share repurchases & issuance (net)——−$569,000−$569,000——−$469,000$186.7M$3.0M−$137,000
Net borrowing (repayment)−$16.2M$7.1M$13.5M−$6.6M−$12.5M$17.6M−$3.4M−$127,000−$41,000−$91,000
Shares issued$44,000$82.8M$67.9M$13.2M$48.5M$9.2M$0$236.6M$0$0
Other financing−$49,968−$158,911$2.0M−$4.3M$11.5M$553,000$0−$186.7M$38.3M$688,645
Cash from financing activities−$16.2M$89.8M$82.9M$1.1M$47.5M$27.3M−$3.9M$236.5M$41.3M$460,645
Summary
Net change in cash−$79.7M$6.5M$43.5M−$92.4M−$55.5M−$99.4M−$111.0M$195.1M$1.8M−$76.5M
Cash at end of period$63.6M$143.3M$136.7M$93.2M$185.6M$241.1M$340.5M$451.5M$256.4M$254.0M
Free cash flow−$42.5M$19.5M−$25.8M−$89.9M−$123.1M−$124.7M−$82.1M−$73.0M−$55.0M−$44.4M
Free cash flow margin−58.3%47.0%−3,419.7%−468.9%−166.5%−168.6%−540.5%−573.6%−218.3%−104.3%
Capex / revenue3.2%6.2%142.1%12.7%25.1%60.1%85.3%38.4%10.5%31.3%

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

CLLS cash generation

In fiscal 2025 (ended December 31, 2025), Cellectis generated -$40.1 million of cash from operations (down 281.6%) and spent $2.4 million on capital expenditures, leaving free cash flow of -$42.5 million, −58.3% of revenue. Cash and equivalents fell by $79.7 million over the year.

Related: CLLS income statement, CLLS balance sheet. See the CLLS stock overview for the latest quote and news.

CLLS cash flow FAQ

What is Cellectis's free cash flow?

Cellectis's free cash flow was -$42.5 million in fiscal 2025: -$40.1 million of operating cash flow minus $2.4 million of capital expenditures It was $19.5 million a year earlier..

How much cash does Cellectis generate from operations?

Cellectis generated -$40.1 million of cash from operating activities in fiscal 2025.

How much does Cellectis spend on capital expenditures?

Cellectis spent $2.4 million on capital expenditures in fiscal 2025, 3.2% of revenue, compared with $2.6 million the year before.

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