Spero Therapeutics, Inc. (SPRO) Stock Chart

NASDAQ: SPROInteractive price chart with technical indicators, performance and price history.

SPRO price chart

Daily prices adjusted for splits and dividends. 1D and 5D show delayed intraday prices. Markers: E earnings, D dividend, S split.

Technical snapshot

Key levels & statistics

SPRO performance vs the market

Total return, dividends reinvested

SPRO monthly returns

SPRO historical prices

SPRO dividends & splits

About the SPRO chart

Spero Therapeutics (SPRO) closed at $1.10 on October 16, 2026, down 52.8% so far this year. The stock is trading 46.4% below its 200-day moving average of $2.05, which technical analysts usually read as a long-term downtrend. Over the past year SPRO returned −53.2% including dividends, behind the S&P 500 (+16.8%).

This page charts the full trading history of Spero Therapeutics, Inc. stock. Daily prices come from EODHD and are adjusted for stock splits and dividends, so returns over long periods are comparable. For the latest quote, company profile, earnings and news, see the SPRO stock overview.

SPRO chart FAQ

What is Spero Therapeutics's all-time high stock price?

The highest closing price for SPRO was $22.07 on December 28, 2020 (adjusted for stock splits). As of the October 16, 2026 close it traded 95.0% below that level.

What is the 52-week range of SPRO stock?

Over the 52 weeks to October 16, 2026, SPRO traded between an intraday low of $1.08 on July 24, 2026 and an intraday high of $3.08 on May 27, 2026.

Is SPRO above its 200-day moving average?

No. On October 16, 2026 SPRO closed at $1.10, 46.4% below its 200-day simple moving average of $2.05. The 50-day average was $1.19.

How has SPRO stock performed compared with the S&P 500?

Including reinvested dividends, SPRO returned −53.2% over the past year, compared with +16.8% for the S&P 500 (SPY). Over five years the figures were −93.5% and +83.0%.

Does Spero Therapeutics pay a dividend?

Spero Therapeutics has not paid a dividend in the past 12 months.

How do I read the SPRO chart?

Pick a time range above the chart and choose candlesticks, a line or an area chart. Moving averages, Bollinger Bands, volume, RSI and MACD can be switched on with the indicator buttons, and "Compare" plots SPRO against the S&P 500, its sector or a competitor as a percentage change. Chart prices are adjusted for splits and dividends.

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