Orchestra BioMed Holdings, Inc. (OBIO) Cash Flow Statement

NASDAQ: OBIOOperating cash, capex, free cash flow and buybacks.

Where OBIO’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$49.0M
Capital expenditures
$489,000
1.5% of revenue
Free cash flow
−$49.5M
−147.7% margin
Returned to shareholders
—
Change in cash
$12.4M
cash at year-end $34.7M
Shares issued: $71.9MShares issued$71.9MOther financing: $16.5MOther financing$16.5MCash used in operations: $49.0MCash used in operations$49.0M · 55%Investments (net): $26.5MInvestments (net)$26.5M · 30%Added to cash: $12.4MAdded to cash$12.4M · 14%Capital expenditures: $489,000Capital expenditures$489,000 · 1%$88.3M
Cash from operations
−$49.0M
Capital expenditures
−$489,000
Investments (net)
−$26.5M
Shares issued
+$71.9M
Other financing
+$16.5M
Change in cash
$12.4M

Drawn to scale: where the cash came from and how it was used. Hover for values.

OBIO operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

OBIO cash flow trends, 2020–2025

Orchestra BioMed Holdings, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$26.2M2020−$49.0M2025—
Capital expenditures$539,0002020$489,0002025−1.9%/yr
Free cash flow−$26.7M2020−$49.5M2025—
Free cash flow margin−468.6%2020−147.7%2025+320.9 pts
Stock-based compensation$221,0002020$12.0M2025+122.2%/yr
Capex / revenue9.5%20201.5%2025−8.0 pts

Change is the average annual growth (CAGR) or the difference between the first and latest year.

OBIO cash flow by activity

OperatingInvestingFinancingChange in cash

OBIO net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

OBIO cash flow statement

Orchestra BioMed Holdings, Inc. annual cash flow statement
202520242023202220212020
Operating activities
Net income−$52.7M−$61.0M−$49.1M−$33.6M−$23.0M−$21.4M
Depreciation & amortization$327,000$308,000$287,000$222,000$181,000$137,000
Stock-based compensation$12.0M$10.6M$7.6M$3.4M$302,000$221,000
Change in working capital−$10.4M−$765,000−$3.3M−$451,000$2.6M−$8.1M
Other non-cash items$1.8M$308,000−$1.6M$1.1M$505,000$2.9M
Cash from operating activities−$49.0M−$50.6M−$46.1M−$29.3M−$19.4M−$26.2M
Investing activities
Capital expenditures−$489,000−$289,000−$78,000−$591,000−$274,000−$539,000
Investments (net)−$26.5M$13.1M$10.7M−$64.1M$13.0M$27.0M
Acquisitions & other investing$0$289,000$78,000$591,000$274,000$539,000
Cash from investing activities−$26.9M$13.1M$10.7M−$64.1M$13.0M$27.0M
Financing activities
Share repurchases & issuance (net)———−$92.6M——
Net borrowing (repayment)$0$15.0M−$10.8M$3.6M−$4.0M$10.0M
Shares issued$71.9M$15.0M$0$109.8M$0$0
Other financing$16.5M−$864,000$57.1M$82.5M$7,000$0
Cash from financing activities$88.3M$29.2M$46.2M$103.3M−$4.0M$10.0M
Summary
Net change in cash$12.4M−$8.3M$10.8M$9.8M−$10.4M$10.8M
Cash at end of period$34.7M$22.3M$30.6M$19.8M$9.9M$20.3M
Free cash flow−$49.5M−$50.8M−$46.2M−$29.9M−$19.7M−$26.7M
Free cash flow margin−147.7%−1,927.5%−1,674.1%−845.7%—−468.6%
Capex / revenue1.5%11.0%2.8%16.7%—9.5%

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

OBIO cash generation

In fiscal 2025 (ended December 31, 2025), Orchestra BioMed generated -$49.0 million of cash from operations and spent $0.5 million on capital expenditures, leaving free cash flow of -$49.5 million, −147.7% of revenue. Cash and equivalents rose by $12.4 million over the year.

Related: OBIO income statement, OBIO balance sheet. See the OBIO stock overview for the latest quote and news.

OBIO cash flow FAQ

What is Orchestra BioMed's free cash flow?

Orchestra BioMed's free cash flow was -$49.5 million in fiscal 2025: -$49.0 million of operating cash flow minus $0.5 million of capital expenditures It was -$50.8 million a year earlier..

How much cash does Orchestra BioMed generate from operations?

Orchestra BioMed generated -$49.0 million of cash from operating activities in fiscal 2025.

How much does Orchestra BioMed spend on capital expenditures?

Orchestra BioMed spent $0.5 million on capital expenditures in fiscal 2025, 1.5% of revenue, compared with $0.3 million the year before.

Biotechnology: cash flow