Intellia Therapeutics, Inc. (NTLA) Cash Flow Statement

NASDAQ: NTLAOperating cash, capex, free cash flow and buybacks.

Where NTLA’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$348.9M
Capital expenditures
$5.8M
8.5% of revenue
Free cash flow
−$354.7M
−524.1% margin
Returned to shareholders
—
Change in cash
−$37.6M
cash at year-end $202.8M
Investments (net): $229.2MInvestments (net)$229.2MShares issued: $128.2MShares issued$128.2MOther financing: $57.6MOther financing$57.6MDrawn from cash: $37.6MDrawn from cash$37.6MCash used in operations: $348.9MCash used in operations$348.9M · 77%Acquisitions & other: $97.8MAcquisitions & other$97.8M · 22%Capital expenditures: $5.8MCapital expenditures$5.8M · 1%$452.5M
Cash from operations
−$348.9M
Capital expenditures
−$5.8M
Investments (net)
+$229.2M
Acquisitions & other
−$97.8M
Shares issued
+$128.2M
Other financing
+$57.6M
Change in cash
−$37.6M

Drawn to scale: where the cash came from and how it was used. Hover for values.

NTLA operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

NTLA cash flow trends, 2016–2025

Intellia Therapeutics, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow$36.1M2016−$348.9M2025—
Capital expenditures$6.2M2016$5.8M2025−0.7%/yr
Free cash flow$29.9M2016−$354.7M2025—
Free cash flow margin181.7%2016−524.1%2025−705.8 pts
Stock-based compensation$6.7M2016$154.3M2025+41.7%/yr
Dividends paid$02016$02017—
Share buybacks (net)$100,0002016$02022−100.0%
Capex / revenue37.4%20168.5%2025−28.9 pts

Change is the average annual growth (CAGR) or the difference between the first and latest year.

NTLA cash flow by activity

OperatingInvestingFinancingChange in cash

NTLA net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

NTLA cash flow statement

Intellia Therapeutics, Inc. annual cash flow statement
2025202420232022202120202019201820172016
Operating activities
Net income−$519.0M−$519.0M−$481.2M−$474.2M−$267.9M−$134.2M−$99.5M−$85.3M−$67.5M−$31.6M
Depreciation & amortization$15.9M$10.3M$9.0M$7.6M$6.9M$6.3M$5.6M$4.5M$3.0M$1.1M
Stock-based compensation$154.3M$154.3M$134.1M$91.4M$47.0M$19.9M$15.1M$17.0M$15.3M$6.7M
Change in working capital−$73.8M$11.9M−$52.5M−$53.9M−$22.9M$57.5M−$20.7M$3.2M−$16.2M$59.9M
Other non-cash items$73.7M−$6.3M−$3.5M$95.8M$11.9M$573,000−$3.7M−$601,000$166,000$13,000
Cash from operating activities−$348.9M−$348.9M−$394.1M−$333.3M−$225.0M−$49.9M−$103.2M−$61.3M−$65.3M$36.1M
Investing activities
Capital expenditures−$5.8M−$5.8M−$14.0M−$58.4M−$12.8M−$3.6M−$6.8M−$6.4M−$10.1M−$6.2M
Investments (net)$229.2M$125.6M−$107.4M$160.3M−$535.0M−$210.9M$32.0M−$254.6M−$10.1M−$6.2M
Acquisitions & other investing−$97.8M$5.8M$90.1M$58.4M−$3.0M$0$0$131,000$10.1M$6.2M
Cash from investing activities$125.6M$125.6M−$31.3M$160.3M−$550.8M−$214.5M$25.2M−$260.8M−$10.1M−$6.2M
Financing activities
Dividends paid————————$0$0
Share repurchases & issuance (net)———$583.0M$1.86B$371.8M$76.4M$40.2M$143.0M−$100,000
Shares issued$128.2M$176.9M$519.8M$565.8M$693.6M$358.6M$72.3M$29.0M$0$0
Other financing$57.6M$8.8M−$389.5M−$565.8M−$1.82B−$358.6M−$72.3M−$29.0M$0$167.4M
Cash from financing activities$185.7M$185.7M$130.3M$583.0M$736.7M$371.8M$76.4M$40.2M$143.0M$167.3M
Summary
Net change in cash−$37.6M−$37.6M−$295.1M$410.0M−$39.1M$107.4M−$1.6M−$281.8M$67.6M$197.2M
Cash at end of period$202.8M$202.8M$240.4M$535.5M$125.5M$164.6M$57.2M$58.9M$340.7M$273.1M
Free cash flow−$354.7M−$354.7M−$408.1M−$391.7M−$237.8M−$53.5M−$110.0M−$67.6M−$75.4M$29.9M
Free cash flow margin−524.1%−612.8%−1,124.9%−751.5%−719.4%−92.2%−255.3%−222.2%−288.6%181.7%
Capex / revenue8.5%10.0%38.6%112.0%38.6%6.2%15.8%20.9%38.6%37.4%

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

NTLA cash generation

In fiscal 2025 (ended December 31, 2025), Intellia Therapeutics generated -$348.9 million of cash from operations and spent $5.8 million on capital expenditures, leaving free cash flow of -$354.7 million, −524.1% of revenue. Cash and equivalents fell by $37.6 million over the year.

Related: NTLA income statement, NTLA balance sheet. See the NTLA stock overview for the latest quote and news.

NTLA cash flow FAQ

What is Intellia Therapeutics's free cash flow?

Intellia Therapeutics's free cash flow was -$354.7 million in fiscal 2025: -$348.9 million of operating cash flow minus $5.8 million of capital expenditures It was -$354.7 million a year earlier..

How much cash does Intellia Therapeutics generate from operations?

Intellia Therapeutics generated -$348.9 million of cash from operating activities in fiscal 2025.

How much does Intellia Therapeutics spend on capital expenditures?

Intellia Therapeutics spent $5.8 million on capital expenditures in fiscal 2025, 8.5% of revenue, compared with $5.8 million the year before.

Biotechnology: cash flow