TScan Therapeutics, Inc. (TCRX) Key Metrics

NASDAQ: TCRXValuation, returns, debt and efficiency ratios over 7 years.

TCRX valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$15.1M
Enterprise value
$15.4M
P/E (TTM)
—
Forward P/E
—
PEG ratio
—
Price / sales
2.2
10-yr median 12.6
Price / book
0.4
10-yr median 1.1
EV / EBITDA
0.4
Dividend yield
—
Beta
1.14

TCRX key metrics, 2019–2025

Fiscal year ended December 31, 2025 · U.S. dollars

TCRX valuation Price multiples at each fiscal year-end price.

Price / sales−89.6%
12.6
2025 · hover or tap a bar for each year
2021: 10.62022: 2.8 (−74.0%)2023: 18.2 (+559.8%)2024: 120.9 (+565.4%)2025: 12.6 (−89.6%)
20192025
Price / book−25.3%
1.1
2025 · hover or tap a bar for each year
2021: 0.72022: 0.4 (−44.0%)2023: 2.5 (+576.2%)2024: 1.4 (−44.3%)2025: 1.1 (−25.3%)
20192025
Free cash flow yield−73.9 pts
−107.6%
2025 · hover or tap a bar for each year
2021: −54.5%2022: −189.7% (−135.3 pts)2023: −16.9% (+172.9 pts)2024: −33.7% (−16.8 pts)2025: −107.6% (−73.9 pts)
20192025

TCRX valuation history

Fiscal year-endToday7-year median

TCRX returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

TCRX debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

TCRX price vs earnings per share

Share price at year-endEPS (right axis)

TCRX key metrics

2019–2025
TScan Therapeutics, Inc. key metrics by fiscal year
2025202420232022202120202019
Valuation
Market capitalization$129.9M$340.5M$382.4M$37.3M$107.6M——
Enterprise value$71.6M$147.7M$282.8M$3.2M−$47.8M——
Price / sales12.6120.918.22.810.6——
Price / book1.11.42.50.40.7——
EV / sales6.952.513.40.2-4.7——
Earnings yield−99.9%−37.5%−23.3%−177.7%−45.2%——
Free cash flow yield−107.6%−33.7%−16.9%−189.7%−54.5%——
Dividend yield0.0%0.0%—————
Shareholder yield (dividends + buybacks)0.0%0.0%—0.0%0.0%——
Share price at fiscal year-end$1.00$3.04$5.83$1.55$4.50——
Per share
Revenue per share$0.08$0.03$0.32$0.56$0.42$0.04$0.00
Earnings per share−$1.00−$1.14−$1.36−$2.75−$2.03−$1.05−$0.55
Operating cash flow per share−$1.04−$0.99−$0.94−$2.77−$2.04−$0.12−$0.50
Free cash flow per share−$1.08−$1.02−$0.98−$2.94−$2.45−$0.29−$0.55
Cash per share$1.17$2.59$2.93$4.99$6.75$1.40$1.67
Book value per share$0.95$2.15$2.30$4.13$6.72−$1.70$1.71
Tangible book value per share$0.95$2.15$2.30$4.13$6.72−$1.70$1.71
Dividends per share$0.00$0.00—————
Capex per share$0.03$0.03$0.05$0.18$0.42$0.17$0.05
Debt per share$0.72$0.87$1.41$3.58$0.25$0.30$0.20
Shares outstanding129.9M112.0M65.6M24.0M23.9M24.9M24.9M
Change in shares outstanding+16.0%+70.7%+172.8%+0.6%−4.1%0.0%—
Returns & profitability
Return on equity (ROE)−71.3%−65.1%−71.3%−50.9%−82.2%—−32.1%
Return on invested capital (ROIC)−189.7%−214.1%−126.6%−148.7%——−198.1%
Return on assets (ROA)−43.3%−39.6%−37.9%−34.2%−40.9%−52.7%−27.7%
Return on tangible assets−56.7%−34.4%−32.8%−33.3%−25.8%−52.5%−27.7%
Free cash flow margin——−306.4%−522.6%−578.0%−669.2%—
Financial health
Total debt$94.1M$97.4M$92.4M$86.0M$6.0M$7.4M$4.9M
Cash & short-term investments$152.4M$290.1M$192.0M$120.0M$161.4M$34.8M$41.8M
Net debt−$58.3M−$192.7M−$99.6M−$34.0M−$155.4M−$27.4M−$36.9M
Debt / equity0.760.400.610.860.04—0.11
Debt / assets0.410.260.340.430.030.150.10
Current ratio8.418.146.517.177.762.0917.69
Quick ratio8.418.146.517.177.762.0917.69
Interest coverage-49.0-36.9-24.9-56.7———
Working capital$138.5M$256.8M$164.4M$106.8M$144.3M$19.0M$40.0M
Invested capital$64.9M$48.2M$51.3M$65.4M$5.4M−$69.8M$5.7M
Tangible asset value$123.1M$241.0M$150.9M$99.4M$160.8M−$42.5M$42.5M
Net current asset value$51.5M$162.6M$73.0M$24.5M$138.3M−$55.8M$35.5M
Graham net-net per share$0.36$1.43$1.08$0.85$5.61−$2.30$1.40
Capital allocation
Dividends paid$0$0—————
Share buybacks (net)$0——$0$0——
Capex / revenue42.7%135.8%14.9%31.2%98.0%390.6%—
Capex / depreciation1.540.930.590.822.993.452.40
Stock-based compensation / revenue113.4%339.1%24.7%33.6%24.8%47.5%—
R&D / revenue1,105.6%3,812.1%418.8%442.0%443.3%1,896.5%—
SG&A / revenue309.8%1,049.7%121.1%150.4%136.4%621.3%—
Efficiency
Days payables outstanding351.4295.510.9166.2256.434.839.0
Payables turnover1.041.2433.352.201.4210.509.35
Asset turnover0.030.010.090.070.090.020.00
Average payables$2.8M$3.3M$2.6M$2.3M$2.3M$2.0M$1.0M
Intangibles / total assets0.0%0.0%0.0%0.0%0.0%0.0%0.0%

Computed from TCRX's annual financial statements (latest annual report filed March 4, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

TCRX valuation and financial ratios

TScan Therapeutics earned a return on equity of −71.3% and a return on invested capital of −189.7% in fiscal 2025. It ended the year with $94.1 million of debt and $152.4 million in cash and short-term investments, a net cash position of $58.3 million. The share count rose 420.7% from 24.9M to 129.9M over 6 years.

See the TCRX income statement, the TCRX chart for price history, or the TCRX stock overview for the latest quote and news.

TCRX key metrics FAQ

What is TScan Therapeutics's return on equity?

TScan Therapeutics's return on equity (ROE) was −71.3% in fiscal 2025: net income of -$129.8 million on average shareholders' equity of $182.0 million.

What is TScan Therapeutics's ROIC?

TScan Therapeutics's return on invested capital was −189.7% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does TScan Therapeutics have?

TScan Therapeutics had total debt of $94.1 million at the end of fiscal 2025, a debt-to-equity ratio of 0.76 and more cash than debt.

Does TScan Therapeutics pay a dividend?

TScan Therapeutics did not pay a dividend in fiscal 2025.

What is TScan Therapeutics's free cash flow yield?

TScan Therapeutics generated -$139.7 million of free cash flow in fiscal 2025, a free cash flow yield of −107.6% on its market value at year-end ($129.9 million).

What is TScan Therapeutics's current ratio?

TScan Therapeutics's current ratio was 8.41 at the end of fiscal 2025: current assets were 8.41 times current liabilities.

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