Senti Biosciences, Inc. (SNTI) Key Metrics

NASDAQ: SNTIValuation, returns, debt and efficiency ratios over 7 years.

SNTI valuation today

Trailing 12 months · as of October 17, 2026
Market cap
$7.0M
Enterprise value
$24.4M
P/E (TTM)
—
Forward P/E
—
PEG ratio
—
Price / sales
127.4
Price / book
5.5
EV / EBITDA
—
Dividend yield
—
Beta
2.22

SNTI key metrics, 2019–2025

Fiscal year ended December 31, 2025 · U.S. dollars

SNTI returns How much profit the business earns on the capital it uses.

Return on equity−279.3 pts
−393.4%
2025 · hover or tap a bar for each year
2019: −117.8%2022: −48.8%2023: −73.2% (−24.4 pts)2024: −114.1% (−40.9 pts)2025: −393.4% (−279.3 pts)
20192025
Return on invested capital−225.3 pts
−346.3%
2025 · hover or tap a bar for each year
2022: −120.2%2023: −109.0% (+11.2 pts)2024: −121.1% (−12.1 pts)2025: −346.3% (−225.3 pts)
20192025
Return on assets−33.9 pts
−82.4%
2025 · hover or tap a bar for each year
2019: −59.0%2020: −47.2% (+11.8 pts)2021: −76.3% (−29.1 pts)2022: −33.0% (+43.3 pts)2023: −47.3% (−14.3 pts)2024: −48.6% (−1.3 pts)2025: −82.4% (−33.9 pts)
20192025
Asset turnover
0.00
2025 · hover or tap a bar for each year
2019: 0.002020: 0.01 (+294.7%)2021: 0.03 (+237.5%)2022: 0.03 (−2.2%)2023: 0.01 (−57.4%)2024: 0.00 (−100.0%)2025: 0.00
20192025

SNTI returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

SNTI debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

SNTI cash returned to shareholders

DividendsBuybacksFree cash flow

SNTI key metrics

2019–2025
Senti Biosciences, Inc. key metrics by fiscal year
2025202420232022202120202019
Valuation
Share price at fiscal year-end$1.04$3.51$6.60$14.10$98.60——
Returns & profitability
Return on equity (ROE)−393.4%−114.1%−73.2%−48.8%——−117.8%
Return on invested capital (ROIC)−346.3%−121.1%−109.0%−120.2%———
Return on assets (ROA)−82.4%−48.6%−47.3%−33.0%−76.3%−47.2%−59.0%
Return on tangible assets−119.9%−54.0%−59.5%−25.3%−57.2%−41.1%−59.0%
Financial health
Total debt$28.9M$33.6M$37.7M$37.1M$22.7M$14.0M—
Cash & short-term investments$16.4M$48.3M$35.9M$98.6M$56.0M$30.5M$17.8M
Net debt$12.5M−$14.6M$1.7M−$61.5M−$33.3M−$16.5M−$17.8M
Debt / equity5.171.310.560.290.38——
Debt / assets0.560.340.320.210.240.29—
Current ratio1.674.495.625.684.046.524.36
Quick ratio1.674.465.625.503.866.514.36
Interest coverage———-18.0—-280.6—
Working capital$9.3M$45.8M$58.5M$84.5M$44.2M$26.8M$14.5M
Invested capital$18.1M$11.0M$68.7M$65.8M$27.1M−$75.2M$136,000
Tangible asset value$5.6M$25.6M$66.9M$127.3M$60.4M−$58.7M$18.0M
Net current asset value−$22.4M−$13.2M$18.6M$49.0M$22.4M−$75.3M$883,000
Capital allocation
Dividends paid——$404,000$5.2M$3,894——
Share buybacks (net)——$0$0———
Capex / revenue890.9%—608.6%965.3%241.9%294.7%2,348.2%
Capex / depreciation0.050.002.2210.551.840.581.43
Stock-based compensation / revenue25,936.4%—488.9%382.5%100.2%69.0%241.2%
R&D / revenue170,845.5%—1,625.4%794.8%958.4%4,049.7%17,087.1%
SG&A / revenue118,922.7%—1,973.9%953.1%927.5%2,361.4%8,638.8%
Efficiency
Days sales outstanding28,204.5—1,691.247.263.7183.0334.9
Days of inventory on hand———274.3159.30.6—
Days payables outstanding220.6—122.4347.0369.924.130.1
Cash conversion cycle (days)27,983.9—1,568.8-25.5-146.8159.4304.9
Receivables turnover0.010.000.227.735.731.991.09
Payables turnover1.65—2.981.050.9915.1212.13
Inventory turnover———1.332.29638.24—
Asset turnover0.000.000.010.030.030.010.00
Average receivables$1.7M$9.8M$9.2M$554,500$400,000$197,500$78,000
Average payables$2.2M$1.4M$1.8M$3.7M$3.1M$1.1M$1.2M
Average inventory—$335,000—$2.9M$1.3M$25,000—
Intangibles / total assets0.0%0.0%0.0%0.0%0.0%0.0%0.0%

Computed from SNTI's annual financial statements (latest annual report filed March 27, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

SNTI valuation and financial ratios

Senti Biosciences earned a return on equity of −393.4% and a return on invested capital of −346.3% in fiscal 2025. It ended the year with $28.9 million of debt and $16.4 million in cash and short-term investments, net debt of $12.5 million.

See the SNTI income statement, the SNTI chart for price history, or the SNTI stock overview for the latest quote and news.

SNTI key metrics FAQ

What is Senti Biosciences's return on equity?

Senti Biosciences's return on equity (ROE) was −393.4% in fiscal 2025: net income of -$61.4 million on average shareholders' equity of $15.6 million.

What is Senti Biosciences's ROIC?

Senti Biosciences's return on invested capital was −346.3% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does Senti Biosciences have?

Senti Biosciences had total debt of $28.9 million at the end of fiscal 2025, a debt-to-equity ratio of 5.17.

What is Senti Biosciences's current ratio?

Senti Biosciences's current ratio was 1.67 at the end of fiscal 2025: current assets were 1.67 times current liabilities.

Biotechnology key metrics