Phio Pharmaceuticals Corp. (PHIO) Key Metrics

NASDAQ: PHIOValuation, returns, debt and efficiency ratios over 10 years.

PHIO valuation today

Trailing 12 months · as of October 17, 2026
Market cap
$10.1M
Enterprise value
−$1.1M
P/E (TTM)
—
Forward P/E
0.3
PEG ratio
—
Price / sales
48.0
Price / book
0.9
EV / EBITDA
0.6
Dividend yield
—
Beta
0.84

PHIO key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

PHIO returns How much profit the business earns on the capital it uses.

Return on equity+44.9 pts
−69.9%
2025 · hover or tap a bar for each year
2016: −91.1% (+23.9 pts)2017: −196.3% (−105.2 pts)2018: −95.5% (+100.8 pts)2019: −91.5% (+4.0 pts)2020: −93.7% (−2.2 pts)2021: −75.6% (+18.1 pts)2022: −69.0% (+6.6 pts)2023: −116.6% (−47.6 pts)2024: −114.8% (+1.8 pts)2025: −69.9% (+44.9 pts)
20162025
Return on assets+30.8 pts
−63.9%
2025 · hover or tap a bar for each year
2016: −73.3% (+18.4 pts)2017: −142.3% (−69.1 pts)2018: −75.8% (+66.6 pts)2019: −75.7% (+0.1 pts)2020: −74.0% (+1.7 pts)2021: −64.6% (+9.4 pts)2022: −59.5% (+5.1 pts)2023: −97.6% (−38.1 pts)2024: −94.7% (+2.9 pts)2025: −63.9% (+30.8 pts)
20162025
Asset turnover
0.00
2025 · hover or tap a bar for each year
2016: 0.00 (−49.2%)2017: 0.00 (+10.8%)2018: 0.01 (+728.8%)2019: 0.00 (−87.3%)2020: 0.00 (−79.6%)2021: 0.00 (−100.0%)2022: 0.002023: 0.002024: 0.002025: 0.00
20162025

PHIO valuation history

Fiscal year-endToday10-year median

PHIO returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

PHIO debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

PHIO cash returned to shareholders

DividendsBuybacksFree cash flow

PHIO price vs earnings per share

Share price at year-endEPS (right axis)

PHIO key metrics

2016–2025
Phio Pharmaceuticals Corp. key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$6.3M—————————
Enterprise value−$14.7M—————————
Price / book0.3—————————
Earnings yield−138.4%—————————
Free cash flow yield−127.2%—————————
Shareholder yield (dividends + buybacks)0.0%—————————
Share price at fiscal year-end$1.05$1.80$6.84$40.18$108.00$290.52$1,015.74$1,960.20$33,026.40$42,471.00
Per share
Revenue per share$0.00—————————
Earnings per share−$1.45—————————
Operating cash flow per share−$1.33—————————
Free cash flow per share−$1.34—————————
Cash per share$3.51—————————
Book value per share$3.37—————————
Tangible book value per share$3.37—————————
Capex per share$0.00—————————
Shares outstanding6.0M—————————
Returns & profitability
Return on equity (ROE)−69.9%−114.8%−116.6%−69.0%−75.6%−93.7%−91.5%−95.5%−196.3%−91.1%
Return on assets (ROA)−63.9%−94.7%−97.6%−59.5%−64.6%−74.0%−75.7%−75.8%−142.3%−73.3%
Return on tangible assets−40.5%−124.6%−115.6%−88.2%−52.5%−55.9%−110.0%−48.0%−303.9%−67.1%
Financial health
Total debt——$35,000$170,000$295,000$642,000$518,000———
Cash & short-term investments$21.0M$5.4M$8.5M$11.8M$24.1M$14.2M$6.9M$14.9M$3.6M$12.9M
Net debt−$21.0M−$5.4M−$8.5M−$11.6M−$23.8M−$13.6M−$6.4M−$14.9M−$3.6M−$12.9M
Debt / equity——0.000.020.010.050.09———
Debt / assets——0.000.010.010.040.06———
Current ratio49.375.655.716.428.066.913.888.691.695.16
Quick ratio49.375.655.716.428.066.913.888.691.695.16
Interest coverage—-32.0—-65.5——————
Working capital$21.0M$4.7M$7.7M$10.5M$21.7M$13.0M$5.4M$13.4M$1.6M$10.6M
Invested capital−$884,000−$659,000−$725,000−$771,000−$1.8M−$585,000−$668,000−$1.3M−$1.7M−$2.1M
Tangible asset value$20.1M$4.7M$7.7M$10.8M$21.9M$13.0M$5.7M$13.6M$1.8M$10.9M
Net current asset value$20.1M$4.7M$7.7M$10.5M$21.5M$12.4M$5.0M$13.4M$1.6M$10.6M
Graham net-net per share$3.29—————————
Capital allocation
Dividends paid—————$4.1M$1,000———
Share buybacks (net)$0$1,000$11,000$28$1$15,000$0$0$0$0
Capex / revenue—————435.6%342.9%3.6%1,353.3%21.1%
Capex / depreciation4.000.030.030.630.680.261.070.062.900.08
Stock-based compensation / revenue—————3,117.8%1,428.6%204.3%2,093.3%3,978.9%
R&D / revenue—————85,190.3%20,476.2%3,134.8%35,800.0%28,500.0%
SG&A / revenue—————116,391.6%22,419.0%2,301.4%26,740.0%19,047.4%
Efficiency
Days payables outstanding27.245.641.41,004.2961.075.557.744.848.570.1
Payables turnover13.428.018.820.360.384.846.338.157.525.21
Asset turnover0.000.000.000.000.000.000.000.010.000.00
Average payables$344,000$455,000$718,000$531,000$505,500$768,500$679,500$530,500$714,000$1.0M
Intangibles / total assets0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%

Computed from PHIO's annual financial statements (latest annual report filed March 5, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

PHIO valuation and financial ratios

Phio Pharmaceuticals earned a return on equity of −69.9% in fiscal 2025.

See the PHIO income statement, the PHIO chart for price history, or the PHIO stock overview for the latest quote and news.

PHIO key metrics FAQ

What is Phio Pharmaceuticals's return on equity?

Phio Pharmaceuticals's return on equity (ROE) was −69.9% in fiscal 2025: net income of -$8.7 million on average shareholders' equity of $12.4 million.

What is Phio Pharmaceuticals's free cash flow yield?

Phio Pharmaceuticals generated -$8.0 million of free cash flow in fiscal 2025, a free cash flow yield of −127.2% on its market value at year-end ($6.3 million).

What is Phio Pharmaceuticals's current ratio?

Phio Pharmaceuticals's current ratio was 49.37 at the end of fiscal 2025: current assets were 49.37 times current liabilities.

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