Phio Pharmaceuticals Corp. (PHIO) Cash Flow Statement

NASDAQ: PHIOOperating cash, capex, free cash flow and buybacks.

Where PHIO’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$8.0M
Capital expenditures
$12,000
Free cash flow
−$8.0M
Returned to shareholders
—
Change in cash
$15.6M
cash at year-end $21.0M
Shares issued: $17.9MShares issued$17.9MOther financing: $5.7MOther financing$5.7MCash used in operations: $8.0MCash used in operations$8.0M · 34%Added to cash: $15.6MAdded to cash$15.6M · 66%Capital expenditures: $12,000Capital expenditures$12,000 · 0%$23.6M
Cash from operations
−$8.0M
Shares issued
+$17.9M
Other financing
+$5.7M
Change in cash
$15.6M

Drawn to scale: where the cash came from and how it was used. Hover for values.

PHIO operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

PHIO cash flow trends, 2016–2025

Phio Pharmaceuticals Corp. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$7.8M2016−$8.0M2025—
Capital expenditures$4,0002016$12,0002025+13.0%/yr
Free cash flow−$7.8M2016−$8.0M2025—
Free cash flow margin−40,863.2%2016−202,223.8%2020−161,360.6 pts
Stock-based compensation$756,0002016$481,0002025−4.9%/yr
Dividends paid$1,0002019$4.1M2020+408,600.0%/yr
Share buybacks (net)$02016$02025—
Capex / revenue21.1%2016435.6%2020+414.5 pts

Change is the average annual growth (CAGR) or the difference between the first and latest year.

PHIO cash flow by activity

OperatingInvestingFinancingChange in cash

PHIO net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

PHIO cash flow statement

Phio Pharmaceuticals Corp. annual cash flow statement
2025202420232022202120202019201820172016
Operating activities
Net income−$8.7M−$7.2M−$10.8M−$11.5M−$13.3M−$8.8M−$8.9M−$7.4M−$12.5M−$9.0M
Depreciation & amortization$3,000$35,000$184,000$193,000$75,000$72,000$67,000$81,000$70,000$53,000
Stock-based compensation$481,000$147,000$303,000$414,000$480,000$136,000$300,000$282,000$314,000$756,000
Change in working capital$235,000−$138,000−$536,000−$1.3M$990,000−$327,000−$213,000−$523,000−$530,000$434,000
Other non-cash items$0−$6,000$126,000$0−$116,000$111,000$109,000$0$3.1M−$9,000
Cash from operating activities−$8.0M−$7.1M−$10.7M−$12.1M−$11.9M−$8.8M−$8.6M−$7.5M−$9.5M−$7.8M
Investing activities
Capital expenditures−$12,000−$1,000−$5,000−$121,000−$51,000−$19,000−$72,000−$5,000−$203,000−$4,000
Investments (net)—$8,000−$5,000−$121,000−$51,000−$19,000−$72,000−$5,000−$103,000$5.3M
Acquisitions & other investing$0$1,000$5,000$121,000$51,000$19,000$72,000$5,000$203,000$0
Cash from investing activities−$12,000$8,000−$5,000−$121,000−$51,000−$19,000−$72,000−$5,000−$103,000$5.3M
Financing activities
Dividends paid—————−$4.1M−$1,000———
Share repurchases & issuance (net)$0−$1,000−$11,000−$28−$1−$15,000$1,000$3,000$2,000$10.2M
Net borrowing (repayment)————$0$204,000−$6,000−$6,000−$6,000−$6,000
Shares issued$17.9M$4.0M$5.0M$2,000$19.6M$12.1M$781,000$18.7M$0$0
Other financing$5.7M−$5,000$2.4M−$27,972$2.1M$7.9M−$3,000$108,000$296,000$6,000
Cash from financing activities$23.6M$4.0M$7.4M−$26,000$21.7M$16.1M$772,000$18.8M$292,000$10.2M
Summary
Net change in cash$15.6M−$3.1M−$3.3M−$12.3M$9.8M$7.3M−$7.9M$11.3M−$9.3M$7.8M
Cash at end of period$21.0M$5.4M$8.5M$11.8M$24.1M$14.3M$7.0M$14.9M$3.6M$12.9M
Free cash flow−$8.0M−$7.1M−$10.8M−$12.2M−$11.9M−$8.8M−$8.7M−$7.5M−$9.7M−$7.8M
Free cash flow margin—————−202,223.8%−41,509.5%−5,452.9%−64,780.0%−40,863.2%
Capex / revenue—————435.6%342.9%3.6%1,353.3%21.1%

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

PHIO cash generation

In fiscal 2025 (ended December 31, 2025), Phio Pharmaceuticals generated -$8.0 million of cash from operations and spent $0.0 million on capital expenditures, leaving free cash flow of -$8.0 million. Cash and equivalents rose by $15.6 million over the year.

Related: PHIO income statement, PHIO balance sheet. See the PHIO stock overview for the latest quote and news.

PHIO cash flow FAQ

What is Phio Pharmaceuticals's free cash flow?

Phio Pharmaceuticals's free cash flow was -$8.0 million in fiscal 2025: -$8.0 million of operating cash flow minus $0.0 million of capital expenditures It was -$7.1 million a year earlier..

How much cash does Phio Pharmaceuticals generate from operations?

Phio Pharmaceuticals generated -$8.0 million of cash from operating activities in fiscal 2025.

How much does Phio Pharmaceuticals spend on capital expenditures?

Phio Pharmaceuticals spent $0.0 million on capital expenditures in fiscal 2025, compared with $0.0 million the year before.

Biotechnology: cash flow