Mineralys Therapeutics, Inc. (MLYS) Key Metrics

NASDAQ: MLYSValuation, returns, debt and efficiency ratios over 6 years.

MLYS valuation today

Trailing 12 months · as of October 17, 2026
Market cap
$1.79B
Enterprise value
$1.72B
P/E (TTM)
—
Forward P/E
—
PEG ratio
—
Price / sales
—
Price / book
4.3
10-yr median 3.1
EV / EBITDA
—
Dividend yield
—
Beta
0.69

MLYS key metrics, 2020–2025

Fiscal year ended December 31, 2025 · U.S. dollars

MLYS valuation Price multiples at each fiscal year-end price.

Price / book+21.5%
3.8
2025 · hover or tap a bar for each year
2023: 1.32024: 3.1 (+142.1%)2025: 3.8 (+21.5%)
20202025
Free cash flow yield+22.0 pts
−5.8%
2025 · hover or tap a bar for each year
2023: −26.1%2024: −27.8% (−1.8 pts)2025: −5.8% (+22.0 pts)
20202025

MLYS valuation history

Fiscal year-endToday6-year median

MLYS returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

MLYS debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

MLYS cash returned to shareholders

DividendsBuybacksFree cash flow

MLYS price vs earnings per share

Share price at year-endEPS (right axis)

MLYS key metrics

2020–2025
Mineralys Therapeutics, Inc. key metrics by fiscal year
202520242023202220212020
Valuation
Market capitalization$2.46B$597.5M$311.2M———
Enterprise value$1.80B$399.3M$74.7M———
Price / book3.83.11.3———
Earnings yield−6.3%−29.8%−23.1%———
Free cash flow yield−5.8%−27.8%−26.1%———
Shareholder yield (dividends + buybacks)0.0%0.0%0.0%———
Share price at fiscal year-end$36.29$12.31$8.60———
Per share
Revenue per share$0.00$0.00$0.00———
Earnings per share−$2.29−$3.66−$1.99———
Operating cash flow per share−$2.10−$3.43−$2.24———
Free cash flow per share−$2.11−$3.43−$2.24———
Cash per share$9.71$4.08$6.54———
Book value per share$9.56$3.94$6.66———
Tangible book value per share$9.56$3.94$6.66———
Capex per share$0.00$0.00$0.00———
Shares outstanding67.7M48.5M36.2M———
Change in shares outstanding+39.4%+34.1%————
Returns & profitability
Return on equity (ROE)−36.9%−82.2%−76.1%———
Return on assets (ROA)−35.6%−77.7%−39.3%−47.5%−307.8%−230.6%
Return on tangible assets−23.4%−86.4%−28.6%−26.0%−174.5%−230.6%
Financial health
Total debt—————$4.5M
Cash & short-term investments$656.6M$198.2M$236.6M$110.1M$10.6M$1.4M
Net debt−$656.6M−$198.2M−$236.6M−$110.1M−$10.6M$3.1M
Debt / assets—————3.03
Current ratio43.7614.0223.7613.982.200.29
Quick ratio43.7614.0223.7613.982.200.29
Interest coverage———-18.8-693.5-25.6
Working capital$646.3M$190.7M$238.6M$104.7M$6.1M−$3.6M
Invested capital−$9.9M−$6.9M$4.6M−$162.4M−$33.5M−$506,000
Tangible asset value$646.7M$191.3M$241.2M−$52.3M−$22.9M−$3.6M
Net current asset value$646.3M$190.7M$238.6M−$53.9M−$22.9M−$3.6M
Graham net-net per share$9.48$3.78$6.25———
Capital allocation
Dividends paid—————$3.8M
Share buybacks (net)$0$0$0$1.6M—$20,000
Capex / depreciation0.252.230.000.000.000.00
Efficiency
Days payables outstanding7,720.74,583.7————
Payables turnover0.050.08————
Asset turnover0.000.000.000.000.000.00
Average payables$1.2M$540,000$1.3M$1.3M$646,000$529,000
Intangibles / total assets0.0%0.0%0.0%0.0%0.0%0.0%

Computed from MLYS's annual financial statements (latest annual report filed March 12, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

MLYS valuation and financial ratios

Mineralys Therapeutics earned a return on equity of −36.9% in fiscal 2025.

See the MLYS income statement, the MLYS chart for price history, or the MLYS stock overview for the latest quote and news.

MLYS key metrics FAQ

What is Mineralys Therapeutics's return on equity?

Mineralys Therapeutics's return on equity (ROE) was −36.9% in fiscal 2025: net income of -$154.7 million on average shareholders' equity of $419.0 million.

What is Mineralys Therapeutics's free cash flow yield?

Mineralys Therapeutics generated -$142.4 million of free cash flow in fiscal 2025, a free cash flow yield of −5.8% on its market value at year-end ($2.5 billion).

What is Mineralys Therapeutics's current ratio?

Mineralys Therapeutics's current ratio was 43.76 at the end of fiscal 2025: current assets were 43.76 times current liabilities.

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