Mineralys Therapeutics, Inc. (MLYS) Cash Flow Statement

NASDAQ: MLYSOperating cash, capex, free cash flow and buybacks.

Where MLYS’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$142.4M
Capital expenditures
$15,000
Free cash flow
−$142.4M
Returned to shareholders
—
Change in cash
$58.8M
cash at year-end $172.9M
Shares issued: $578.4MShares issued$578.4MOther financing: $12.4MOther financing$12.4MInvestments (net): $389.7MInvestments (net)$389.7M · 66%Cash used in operations: $142.4MCash used in operations$142.4M · 24%Added to cash: $58.8MAdded to cash$58.8M · 10%Capital expenditures: $15,000Capital expenditures$15,000 · 0%$591.0M
Cash from operations
−$142.4M
Investments (net)
−$389.7M
Shares issued
+$578.4M
Other financing
+$12.4M
Change in cash
$58.8M

Drawn to scale: where the cash came from and how it was used. Hover for values.

MLYS operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

MLYS cash flow trends, 2020–2025

Mineralys Therapeutics, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$2.5M2020−$142.4M2025—
Capital expenditures$02020$15,0002025—
Free cash flow−$2.5M2020−$142.4M2025—
Stock-based compensation$1,0002020$19.3M2025+619.8%/yr
Share buybacks (net)$20,0002020$02025−100.0%

Change is the average annual growth (CAGR) or the difference between the first and latest year.

MLYS cash flow by activity

OperatingInvestingFinancingChange in cash

MLYS net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

MLYS cash flow statement

Mineralys Therapeutics, Inc. annual cash flow statement
202520242023202220212020
Operating activities
Net income−$154.7M−$177.8M−$71.9M−$29.8M−$19.4M−$3.4M
Depreciation & amortization$59,000$43,000$0———
Stock-based compensation$19.3M$11.3M$5.1M$455,000$80,000$1,000
Change in working capital$2.7M$9.5M−$7.5M$772,000$4.1M$480,000
Other non-cash items−$9.9M−$9.4M−$6.9M−$649,000$684,000$482,000
Cash from operating activities−$142.4M−$166.3M−$81.2M−$29.2M−$14.6M−$2.5M
Investing activities
Capital expenditures−$15,000−$96,000$0$0$0$0
Investments (net)−$389.7M$115.0M−$102.4M−$21.8M−$21.8M−$21.8M
Acquisitions & other investing$0$96,000−$58.1M$0$0$0
Cash from investing activities−$389.8M$115.0M−$160.5M−$21.8M−$21.8M−$21.8M
Financing activities
Dividends paid—————−$3.8M
Share repurchases & issuance (net)$243,000$221,000$64,000−$1.6M—−$20,000
Net borrowing (repayment)————$0$3.9M
Shares issued$578.4M$116.1M$203.0M$129.6M$23.8M$0
Other financing$12.4M−$138,000$194,000$0$0$3.8M
Cash from financing activities$591.0M$116.1M$203.2M$128.0M$23.8M$3.8M
Summary
Net change in cash$58.8M$64.8M−$38.4M$77.0M$9.3M$1.4M
Cash at end of period$172.9M$114.1M$49.3M$87.7M$10.7M$1.4M
Free cash flow−$142.4M−$166.4M−$81.2M−$29.2M−$14.6M−$2.5M

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

MLYS cash generation

In fiscal 2025 (ended December 31, 2025), Mineralys Therapeutics generated -$142.4 million of cash from operations and spent $0.0 million on capital expenditures, leaving free cash flow of -$142.4 million. Cash and equivalents rose by $58.8 million over the year.

Related: MLYS income statement, MLYS balance sheet. See the MLYS stock overview for the latest quote and news.

MLYS cash flow FAQ

What is Mineralys Therapeutics's free cash flow?

Mineralys Therapeutics's free cash flow was -$142.4 million in fiscal 2025: -$142.4 million of operating cash flow minus $0.0 million of capital expenditures It was -$166.4 million a year earlier..

How much cash does Mineralys Therapeutics generate from operations?

Mineralys Therapeutics generated -$142.4 million of cash from operating activities in fiscal 2025.

How much does Mineralys Therapeutics spend on capital expenditures?

Mineralys Therapeutics spent $0.0 million on capital expenditures in fiscal 2025, compared with $0.1 million the year before.

Biotechnology: cash flow