Upstream Bio, Inc. (UPB) Stock Chart

NASDAQ: UPBInteractive price chart with technical indicators, performance and price history.

UPB price chart

Daily prices adjusted for splits and dividends. 1D and 5D show delayed intraday prices. Markers: E earnings, D dividend, S split.

Technical snapshot

Key levels & statistics

UPB performance vs the market

Total return, dividends reinvested

UPB monthly returns

UPB historical prices

UPB dividends & splits

About the UPB chart

Upstream Bio (UPB) closed at $2.76 on October 16, 2026, down 89.8% so far this year. The stock is trading 73.9% below its 200-day moving average of $10.57, which technical analysts usually read as a long-term downtrend. Over the past year UPB returned −87.6% including dividends, behind the S&P 500 (+16.8%).

This page charts the full trading history of Upstream Bio, Inc. stock. Daily prices come from EODHD and are adjusted for stock splits and dividends, so returns over long periods are comparable. For the latest quote, company profile, earnings and news, see the UPB stock overview.

UPB chart FAQ

What is Upstream Bio's all-time high stock price?

The highest closing price for UPB was $32.60 on January 13, 2026 (adjusted for stock splits). As of the October 16, 2026 close it traded 91.5% below that level.

What is the 52-week range of UPB stock?

Over the 52 weeks to October 16, 2026, UPB traded between an intraday low of $2.74 on October 16, 2026 and an intraday high of $33.68 on January 14, 2026.

Is UPB above its 200-day moving average?

No. On October 16, 2026 UPB closed at $2.76, 73.9% below its 200-day simple moving average of $10.57. The 50-day average was $5.76.

How has UPB stock performed compared with the S&P 500?

Including reinvested dividends, UPB returned −87.6% over the past year, compared with +16.8% for the S&P 500 (SPY).

Does Upstream Bio pay a dividend?

Upstream Bio has not paid a dividend in the past 12 months.

How do I read the UPB chart?

Pick a time range above the chart and choose candlesticks, a line or an area chart. Moving averages, Bollinger Bands, volume, RSI and MACD can be switched on with the indicator buttons, and "Compare" plots UPB against the S&P 500, its sector or a competitor as a percentage change. Chart prices are adjusted for splits and dividends.

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