Sarepta Therapeutics, Inc. (SRPT) Cash Flow Statement

NASDAQ: SRPTOperating cash, capex, free cash flow and buybacks.

Where SRPT’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$205.5M
Capital expenditures
$102.0M
4.6% of revenue
Free cash flow
−$307.5M
−14.0% margin
Returned to shareholders
$25.0M
Change in cash
−$304.2M
cash at year-end $814.4M
Acquisitions & other: $166.2MAcquisitions & other$166.2MShares issued: $20.0MShares issued$20.0MDrawn from cash: $304.2MDrawn from cash$304.2MInvestments (net): $5.4MInvestments (net)$5.4MCash used in operations: $205.5MCash used in operations$205.5M · 41%Debt repayment: $162.6MDebt repayment$162.6M · 33%Capital expenditures: $102.0MCapital expenditures$102.0M · 21%Share buybacks: $25.0MShare buybacks$25.0M · 5%$495.8M
Cash from operations
−$205.5M
Capital expenditures
−$102.0M
Investments (net)
+$5.4M
Acquisitions & other
+$166.2M
Share buybacks (net)
−$25.0M
Net borrowing (repayment)
−$162.6M
Shares issued
+$20.0M
Change in cash
−$304.2M

Drawn to scale: where the cash came from and how it was used. Hover for values.

SRPT operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

SRPT cash flow trends, 2016–2025

Sarepta Therapeutics, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$245.8M2016−$205.5M2025—
Capital expenditures$6.9M2016$102.0M2025+35.0%/yr
Free cash flow−$252.7M2016−$307.5M2025—
Free cash flow margin−4,661.2%2016−14.0%2025+4,647.3 pts
Stock-based compensation$30.0M2016$123.4M2025+17.0%/yr
Dividends paid$02016$286.3M2020—
Share buybacks (net)$02016$25.0M2025—
Capex / revenue126.7%20164.6%2025−122.0 pts

Change is the average annual growth (CAGR) or the difference between the first and latest year.

SRPT cash flow by activity

OperatingInvestingFinancingChange in cash

SRPT net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

SRPT cash flow statement

Sarepta Therapeutics, Inc. annual cash flow statement
2025202420232022202120202019201820172016
Operating activities
Net income−$713.4M$235.2M−$536.0M−$703.5M−$418.8M−$554.1M−$715.1M−$361.9M−$50.7M−$267.3M
Depreciation & amortization$44.5M$37.7M$44.4M$41.9M$38.0M$39.7M$24.5M$12.2M$8.1M$5.6M
Stock-based compensation$123.4M$184.3M$182.5M$233.0M$113.9M$108.1M$78.6M$50.1M$30.5M$30.0M
Change in working capital$78.0M−$716.6M−$481.1M−$39.5M−$98.2M$554.1M−$66.9M−$107.9M−$97.5M−$15.8M
Other non-cash items$262.0M$53.6M$289.2M$142.7M−$78.2M−$40.3M$222.4M$18.8M−$122.4M$1.6M
Cash from operating activities−$205.5M−$205.8M−$501.0M−$325.3M−$443.2M$107.5M−$456.5M−$388.7M−$232.0M−$245.8M
Investing activities
Capital expenditures−$102.0M−$147.0M−$87.3M−$32.3M−$38.5M−$82.2M−$59.6M−$64.3M−$21.2M−$6.9M
Investments (net)$5.4M$755.6M−$91.6M−$1.05B$436.0M−$144.1M$522.0M−$305.8M−$293.3M−$83.3M
Acquisitions & other investing$166.2M$147.0M$13.2M$32.3M$97.9M$104.6M−$175.6M−$353,000$135.7M$0
Cash from investing activities$69.6M$755.6M−$165.8M−$1.05B$495.4M−$121.7M$286.7M−$370.5M−$178.8M−$90.2M
Financing activities
Dividends paid—————−$286.3M−$240.6M—$0$0
Share repurchases & issuance (net)−$25.0M$0$0—−$7.8M−$4.8M−$4.3M$563.6M$354.0M$364.8M
Net borrowing (repayment)−$162.6M−$68,000$0$304.2M$304.2M$291.1M$244.9M−$3.5M$569.8M−$7.6M
Shares issued$20.0M$0$0$0$548.5M$312.1M$365.4M$513.4M$0$0
Other financing−$743,000$124.9M$125.0M−$71.7M−$283.4M$370.3M$277.2M−$543.4M−$35.7M$20.9M
Cash from financing activities−$168.3M$124.8M$125.0M$232.5M$561.6M$682.3M$642.6M$530.1M$888.1M$378.1M
Summary
Net change in cash−$304.2M$674.6M−$541.8M−$1.14B$613.8M$668.1M$472.8M−$229.0M$477.3M$42.1M
Cash at end of period$814.4M$1.12B$444.0M$985.8M$2.13B$1.51B$843.6M$370.8M$599.8M$122.4M
Free cash flow−$307.5M−$352.7M−$588.3M−$357.6M−$481.7M$25.3M−$516.1M−$453.0M−$253.2M−$252.7M
Free cash flow margin−14.0%−18.5%−47.3%−38.3%−68.6%4.7%−135.5%−150.5%−163.8%−4,661.2%
Capex / revenue4.6%7.7%7.0%3.5%5.5%15.2%15.7%21.4%13.7%126.7%
Operating cash flow / net income—−0.87————————

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

SRPT cash generation

In fiscal 2025 (ended December 31, 2025), Sarepta Therapeutics generated -$205.5 million of cash from operations and spent $102.0 million on capital expenditures, leaving free cash flow of -$307.5 million, −14.0% of revenue. It returned $25.0 million to shareholders through dividends ($0) and net share buybacks ($25.0 million). Cash and equivalents fell by $304.2 million over the year.

Related: SRPT income statement, SRPT balance sheet. See the SRPT stock overview for the latest quote and news.

SRPT cash flow FAQ

What is Sarepta Therapeutics's free cash flow?

Sarepta Therapeutics's free cash flow was -$307.5 million in fiscal 2025: -$205.5 million of operating cash flow minus $102.0 million of capital expenditures It was -$352.7 million a year earlier..

How much cash does Sarepta Therapeutics generate from operations?

Sarepta Therapeutics generated -$205.5 million of cash from operating activities in fiscal 2025.

How much does Sarepta Therapeutics spend on capital expenditures?

Sarepta Therapeutics spent $102.0 million on capital expenditures in fiscal 2025, 4.6% of revenue, compared with $147.0 million the year before.

How much stock does Sarepta Therapeutics buy back?

Sarepta Therapeutics spent $25.0 million on net share repurchases in fiscal 2025.

Biotechnology: cash flow