Shuttle Pharmaceuticals Holdings, Inc. (SHPH) Cash Flow Statement

NASDAQ: SHPHOperating cash, capex, free cash flow and buybacks.

Where SHPH’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$9.5M
Capital expenditures
$5
Free cash flow
−$9.5M
Returned to shareholders
—
Change in cash
−$1.6M
cash at year-end $334,005
Shares issued: $9.5MShares issued$9.5MOther financing: $1.7MOther financing$1.7MDrawn from cash: $1.6MDrawn from cash$1.6MCash used in operations: $9.5MCash used in operations$9.5M · 74%Acquisitions & other: $3.1MAcquisitions & other$3.1M · 24%Debt repayment, Capital expenditures: $190,275Other uses$190,275 · 1%$12.7M
Cash from operations
−$9.5M
Acquisitions & other
−$3.1M
Net borrowing (repayment)
−$190,270
Shares issued
+$9.5M
Other financing
+$1.7M
Change in cash
−$1.6M

Drawn to scale: where the cash came from and how it was used. Hover for values.

SHPH operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

SHPH cash flow trends, 2015–2025

Shuttle Pharmaceuticals Holdings, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$303,5522015−$9.5M2025—
Capital expenditures$4,5542015$52025−53.1%/yr
Free cash flow−$308,1062015−$9.5M2025—
Stock-based compensation$459,5892020$932,9672025+15.2%/yr
Dividends paid$402,0682022$02025−100.0%

Change is the average annual growth (CAGR) or the difference between the first and latest year.

SHPH cash flow by activity

OperatingInvestingFinancingChange in cash

SHPH net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

SHPH cash flow statement

Shuttle Pharmaceuticals Holdings, Inc. annual cash flow statement
2025202420232022202120202018201720162015
Operating activities
Net income−$11.7M−$9.1M−$6.6M−$3.0M−$1.2M−$805,732−$626,139−$213,594−$340,586−$289,991
Depreciation & amortization$290,107$5,463$6,811$66,832$60,834$54,951$18,000$18,739$18,904$18,476
Stock-based compensation$932,967$259,744$181,960$403,956$910,067$459,589————
Change in working capital$540,617$138,911$220,634−$555,205$519,154$7,781$16,647−$9,027——
Other non-cash items$476,333$1.4M$602,171$402,411−$638,257$256,580$24,800$1,177$91,608−$32,037
Cash from operating activities−$9.5M−$7.3M−$5.6M−$2.7M−$300,336−$26,831−$566,692−$202,705−$230,074−$303,552
Investing activities
Capital expenditures−$5−$19,046−$19,046$0−$4−$10,818−$10,818$0−$4,554−$4,554
Investments (net)$0$2.9M−$2.8M$0$0−$10,818————
Acquisitions & other investing−$3.1M$19,046$19,046——$10,818$0—$24,728$29,986
Cash from investing activities−$3.1M$2.9M−$2.8M——−$10,818−$10,818—$20,174$25,432
Financing activities
Dividends paid$0$0—−$402,068——————
Net borrowing (repayment)−$190,270$133,464$3.2M$600,715$687,932$70,073$205,873—$153,860$153,860
Shares issued$9.5M$4.0M$0$10.0M$0$0$0$0$0$0
Other financing$1.7M−$370,946−$679,444$402,068$0$0$662,500$160,617$20,000$146,140
Cash from financing activities$11.0M$3.8M$2.6M$10.6M$687,932$70,073$868,373$160,617$173,860$300,000
Summary
Net change in cash−$1.6M−$656,272−$5.8M$7.9M$387,596$32,424$301,681−$42,088−$36,040$21,880
Cash at end of period$334,005$1.9M$2.6M$8.4M$504,749$117,153$352,390$50,709$117,153—
Free cash flow−$9.5M−$7.3M−$5.6M−$2.7M−$300,336−$37,649−$566,692−$202,705−$234,628−$308,106

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

SHPH cash generation

In fiscal 2025 (ended December 31, 2025), Shuttle Pharmaceuticals generated -$9.5 million of cash from operations and spent $0.0 million on capital expenditures, leaving free cash flow of -$9.5 million. Cash and equivalents fell by $1.6 million over the year.

Related: SHPH income statement, SHPH balance sheet. See the SHPH stock overview for the latest quote and news.

SHPH cash flow FAQ

What is Shuttle Pharmaceuticals's free cash flow?

Shuttle Pharmaceuticals's free cash flow was -$9.5 million in fiscal 2025: -$9.5 million of operating cash flow minus $0.0 million of capital expenditures It was -$7.3 million a year earlier..

How much cash does Shuttle Pharmaceuticals generate from operations?

Shuttle Pharmaceuticals generated -$9.5 million of cash from operating activities in fiscal 2025.

How much does Shuttle Pharmaceuticals spend on capital expenditures?

Shuttle Pharmaceuticals spent $0.0 million on capital expenditures in fiscal 2025, compared with $0.0 million the year before.

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