Protagenic Therapeutics, Inc. (PTIX) Cash Flow Statement

OTC Pink: PTIXOperating cash, capex, free cash flow and buybacks.

Where PTIX’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$4.1M
Capital expenditures
$3
Free cash flow
−$4.1M
Returned to shareholders
—
Change in cash
$4.5M
cash at year-end $2.2M
Acquisitions & other: $943,183Acquisitions & other$943,183Other financing: $4.5MOther financing$4.5MCurrency & other: $3.1MCurrency & other$3.1MCash used in operations: $4.1MCash used in operations$4.1M · 48%Added to cash: $4.5MAdded to cash$4.5M · 52%Capital expenditures: $3Capital expenditures$3 · 0%$8.6M
Cash from operations
−$4.1M
Acquisitions & other
+$943,183
Other financing
+$4.5M
Currency & other
+$3.1M
Change in cash
$4.5M

Drawn to scale: where the cash came from and how it was used. Hover for values.

PTIX operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

PTIX cash flow trends, 2016–2025

Protagenic Therapeutics, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$1.1M2016−$4.1M2025—
Capital expenditures$02016$32025—
Free cash flow−$1.1M2016−$4.1M2025—
Stock-based compensation$546,1342016$562,9512025+0.3%/yr
Dividends paid$02016$02018—
Share buybacks (net)$02016$02018—

Change is the average annual growth (CAGR) or the difference between the first and latest year.

PTIX cash flow by activity

OperatingInvestingFinancingChange in cash

PTIX net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

PTIX cash flow statement

Protagenic Therapeutics, Inc. annual cash flow statement
2025202420232022202120202019201820172016
Operating activities
Net income−$5.2M−$5.5M−$5.0M−$3.6M−$4.5M−$2.5M−$1.8M−$2.6M−$2.3M−$2.3M
Depreciation & amortization$37,714$50,286$28,218$30$427$286$339$347$148$534
Stock-based compensation$562,951$923,139$666,828$864,681$1.5M$1.7M$797,761$1.1M$888,281$546,134
Change in working capital$123,402$467,543−$114,412$540,132−$140,389−$361,431$702,202$109,731−$16,866−$1,937
Other non-cash items$291,838−$132,141$716,087$156,848$345,526−$93,653−$237,381$246,194$7,984$590,776
Cash from operating activities−$4.1M−$4.2M−$3.7M−$2.0M−$2.8M−$1.3M−$487,990−$1.1M−$1.4M−$1.1M
Investing activities
Capital expenditures−$3$0−$149,775−$1,805−$4$0$0$0$0$0
Investments (net)—$2.8M$2.7M$1.6M−$9.9M−$9.9M$250,000$1.0M−$1.3M$0
Acquisitions & other investing$943,183$0$2.3M$1,805$4$0$0$0$0−$1.3M
Cash from investing activities$943,180$2.8M$4.8M$1.6M−$9.9M−$9.9M$250,000$1.0M−$1.3M−$1.3M
Financing activities
Dividends paid———————$0$0$0
Share repurchases & issuance (net)———————$0$0$87
Net borrowing (repayment)———$0$0$1.3M$670,000$670,000$670,000$19,000
Shares issued$0$2.0M$0$0$11.7M$0$0$0$0$0
Other financing$4.5M$0$0$0$869,625−$104,090$0$0$0$4.3M
Cash from financing activities$4.5M$2.0M$0$0$12.6M$1.2M$670,000$670,000$670,000$4.3M
Summary
Net change in cash$4.5M$550,576$1.1M−$325,982−$129,920−$127,532$436,137−$37,201−$2.7M$3.1M
Cash at end of period$2.2M$1.8M$1.3M$215,189$541,171$671,091$798,623$362,486$399,687$3.1M
Free cash flow−$4.1M−$4.2M−$3.9M−$2.0M−$2.8M−$1.3M−$487,990−$1.1M−$1.4M−$1.1M

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

PTIX cash generation

In fiscal 2025 (ended December 31, 2025), Protagenic Therapeutics generated -$4.1 million of cash from operations and spent $0.0 million on capital expenditures, leaving free cash flow of -$4.1 million. Cash and equivalents rose by $4.5 million over the year.

Related: PTIX income statement, PTIX balance sheet. See the PTIX stock overview for the latest quote and news.

PTIX cash flow FAQ

What is Protagenic Therapeutics's free cash flow?

Protagenic Therapeutics's free cash flow was -$4.1 million in fiscal 2025: -$4.1 million of operating cash flow minus $0.0 million of capital expenditures It was -$4.2 million a year earlier..

How much cash does Protagenic Therapeutics generate from operations?

Protagenic Therapeutics generated -$4.1 million of cash from operating activities in fiscal 2025.

How much does Protagenic Therapeutics spend on capital expenditures?

Protagenic Therapeutics spent $0.0 million on capital expenditures in fiscal 2025.

Biotechnology: cash flow