Protagenic Therapeutics, Inc. (PTIX) Income Statement

OTC Pink: PTIXRevenue, profits, margins and EPS over 10 years.

PTIX 2025 at a glance

Fiscal year ended December 31, 2025 · U.S. dollars
Research & development−55.7%
$1.7M
2025 · hover or tap a bar for each year
2016: $417,866 (+89,868.1%)2017: $717,452 (+71.7%)2018: $881,186 (+22.8%)2019: $807,947 (−8.3%)2020: $699,797 (−13.4%)2021: $1.1M (+62.5%)2022: $1.6M (+39.8%)2023: $3.3M (+108.9%)2024: $3.8M (+15.8%)2025: $1.7M (−55.7%)
20162025
Operating expenses+1.8%
$5.8M
2025 · hover or tap a bar for each year
2016: $1.8M (+272.5%)2017: $2.4M (+29.3%)2018: $2.3M (−2.2%)2019: $2.1M (−9.9%)2020: $2.6M (+22.3%)2021: $4.1M (+62.2%)2022: $3.6M (−14.1%)2023: $4.5M (+26.4%)2024: $5.7M (+26.7%)2025: $5.8M (+1.8%)
20162025
Operating income
−$5.8M
2025 · hover or tap a bar for each year
2016: −$2.2M2017: −$2.4M2018: −$2.3M2019: −$2.1M2020: −$2.6M2021: −$4.1M2022: −$3.6M2023: −$4.5M2024: −$5.7M2025: −$5.8M
20162025
Net income
−$5.2M
2025 · hover or tap a bar for each year
2016: −$2.3M2017: −$2.3M2018: −$2.6M2019: −$1.8M2020: −$2.5M2021: −$4.5M2022: −$3.6M2023: −$5.0M2024: −$5.5M2025: −$5.2M
20162025
EPS (diluted)
−$3.45
2025 · hover or tap a bar for each year
2016: −$0.262017: −$0.212018: −$0.252019: −$0.162020: −$0.302021: −$5.812022: −$3.022023: −$1.132024: −$1.892025: −$3.45
20162025

PTIX revenue and net income

RevenueNet incomeNet margin (right axis)

PTIX growth rates

to 2025
1 year3 years5 years10 years
Revenue————
Gross profit————
Operating income————
Net income————
EPS (diluted)————

1-year change and average annual growth (CAGR) over 3, 5 and 10 fiscal years. "—" when a starting value was zero or negative.

PTIX quarterly EPS vs estimates

Reported EPSAnalyst estimate

PTIX income statement

Protagenic Therapeutics, Inc. annual income statement
2025202420232022202120202019201820172016
Revenue$0$0$0$0$0$0$0$0$0$0
Cost of revenue$37,715$50,286$28,218$30—$286$339$347$148$534
Gross profit−$37,715−$50,286−$28,218−$30—−$286−$339−$347−$148−$534
Research & development$1.7M$3.8M$3.3M$1.6M$1.1M$699,797$807,947$881,186$717,452$417,866
Sales, general & admin$1.7M$1.8M$1.2M$2.0M$3.0M$1.9M$1.3M$1.4M$1.6M$1.4M
Total operating expenses$5.8M$5.7M$4.5M$3.6M$4.1M$2.6M$2.1M$2.3M$2.4M$1.8M
Operating income−$5.8M−$5.7M−$4.5M−$3.6M−$4.1M−$2.6M−$2.1M−$2.3M−$2.4M−$2.2M
Interest income—$43,465$303,246$185,790$33,207$502$2,813$2,790$13,890$907
Interest expense$296,895$0$107,682$137,456$496,912$246,178$15,886$2,790$13,890$7,162
Income before taxes−$5.2M−$5.5M−$5.0M−$3.6M−$4.5M−$2.5M−$1.8M−$2.6M−$2.3M−$2.3M
Income taxes——$2$46,051$463,705$246,178$15,886$486,808−$106,000$440,239
Net income−$5.2M−$5.5M−$5.0M−$3.6M−$4.5M−$2.5M−$1.8M−$2.6M−$2.3M−$2.3M
EBITDA−$7.1M−$5.5M−$4.5M−$3.4M−$4.1M−$2.6M−$2.1M−$2.3M−$2.4M−$2.3M
EPS (diluted)−$3.45−$1.89−$1.13−$3.02−$5.81−$0.30−$0.16−$0.25−$0.21−$0.26

Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported in PTIX's financial statements (latest annual report filed March 9, 2026); data from EODHD. Sales, general & administrative expenses include sales and marketing.

PTIX financial results

Protagenic Therapeutics reported no revenue in fiscal year 2025 (ended December 31, 2025). It had a net loss of $5.2 million. Diluted earnings per share came to −$3.45.

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PTIX income statement FAQ

Does Protagenic Therapeutics have revenue?

Protagenic Therapeutics reported no revenue for fiscal year 2025, which ended on December 31, 2025.

Is Protagenic Therapeutics profitable?

No. Protagenic Therapeutics reported a net loss of $5.2 million in fiscal 2025.

How much does Protagenic Therapeutics spend on research and development?

Protagenic Therapeutics spent $1.7 million on research and development in fiscal 2025.

What are Protagenic Therapeutics's earnings per share?

Protagenic Therapeutics earned $-3.45 per diluted share in fiscal 2025, compared with $-1.89 a year earlier.

When does Protagenic Therapeutics's fiscal year end?

Protagenic Therapeutics's fiscal year ends in December. The latest annual report covers the year ended December 31, 2025 and was filed on March 9, 2026.

Biotechnology income statements