NuCana plc (NCNA) Cash Flow Statement

NASDAQ: NCNAOperating cash, capex, free cash flow and buybacks.

Where NCNA’s cash came from and went, 2025

December 31, 2025 · British pounds
Cash from operations
−£7.5M
Capital expenditures
£193,000
Free cash flow
−£7.7M
Returned to shareholders
—
Change in cash
£17.5M
cash at year-end £24.3M
Shares issued: £20.2MShares issued£20.2MOther financing: £4.9MOther financing£4.9MAcquisitions & other: £352,000Acquisitions & other£352,000Cash used in operations: £7.5MCash used in operations£7.5M · 29%Added to cash: £17.5MAdded to cash£17.5M · 69%Capital expenditures, Debt repayment, Currency & other: £443,000Other uses£443,000 · 2%£25.4M
Cash from operations
−£7.5M
Capital expenditures
−£193,000
Acquisitions & other
+£352,000
Net borrowing (repayment)
−£54,000
Shares issued
+£20.2M
Other financing
+£4.9M
Currency & other
−£196,000
Change in cash
£17.5M

Drawn to scale: where the cash came from and how it was used. Hover for values.

NCNA operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

NCNA cash flow trends, 2016–2025

NuCana plc cash flow trends
MetricTrendThenLatestChange
Operating cash flow−£9.3M2016−£7.5M2025—
Capital expenditures£554,0002016£193,0002025−11.1%/yr
Free cash flow−£9.8M2016−£7.7M2025—
Stock-based compensation£1.1M2016£10.0M2025+27.4%/yr
Dividends paid£02016£02019—
Share buybacks (net)£02016£02019—

Change is the average annual growth (CAGR) or the difference between the first and latest year.

NCNA cash flow by activity

OperatingInvestingFinancingChange in cash

NCNA net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

NCNA cash flow statement in British pounds

NuCana plc annual cash flow statement
2025202420232022202120202019201820172016
Operating activities
Net income−£29.4M−£19.0M−£27.6M−£32.0M−£40.5M−£30.7M−£21.4M−£13.8M−£23.1M−£6.0M
Depreciation & amortization£274,000£522,000£575,000£732,000£942,000£890,000£718,000£371,000£194,000£101,000
Stock-based compensation£10.0M£1.6M£3.9M£4.9M£6.7M£4.3M£3.2M£1.8M£11.7M£1.1M
Change in working capital−£3.7M−£2.2M−£1.3M£3.7M£4.1M£1.9M−£2.1M£3.5M£1.4M−£3.2M
Other non-cash items£15.3M−£106,000−£2.0M−£482,000£5.0M£1.9M−£4.3M−£4.0M£1.1M−£1.3M
Cash from operating activities−£7.5M−£19.1M−£26.4M−£23.2M−£23.8M−£21.6M−£23.8M−£12.2M−£8.7M−£9.3M
Investing activities
Capital expenditures−£193,000−£293,000−£478,000−£518,000−£1.1M−£1.6M−£1.3M−£1.6M−£1.1M−£554,000
Investments (net)—£79,000£2.9M£120,000−£3.6M−£1.3M−£145,000−£651,000−£933,000£14.9M
Acquisitions & other investing£352,000£293,000£478,000£518,000£1.1M£1.6M£1.3M£1.6M£1.1M£554,000
Cash from investing activities£159,000£79,000£2.9M£120,000−£3.6M−£1.3M−£145,000−£651,000−£933,000£14.9M
Financing activities
Dividends paid——————£0£0£0£0
Share repurchases & issuance (net)——————£125,000£207,000£80.0M£200,000
Net borrowing (repayment)−£54,000−£223,000−£270,000−£227,000−£296,000−£297,000−£197,000−£197,000−£197,000−£172,000
Shares issued£20.2M£8.7M£249,000£66,000£0£66.6M£125,000£0£0£0
Other financing£4.9M−£322,000−£32,000£0£198,000−£4.5M−£100,000£197,000−£2.0M£172,000
Cash from financing activities£25.0M£8.2M−£53,000−£161,000−£98,000£61.8M−£47,000£207,000£77.7M£200,000
Summary
Net change in cash£17.5M−£10.5M−£24.7M−£18.4M−£27.1M£35.4M−£25.0M−£9.7M£66.7M£5.9M
Cash at end of period£24.3M£6.7M£17.2M£41.9M£60.3M£87.4M£52.0M£77.0M£86.7M£20.0M
Free cash flow−£7.7M−£19.4M−£26.9M−£23.7M−£24.9M−£23.3M−£25.1M−£13.8M−£9.8M−£9.8M
Free cash flow margin————————−3,464.0%—
Capex / revenue————————386.9%—

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in British pounds as reported; data from EODHD.

NCNA cash generation

In fiscal 2025 (ended December 31, 2025), NuCana generated -£7.5 million of cash from operations and spent £0.2 million on capital expenditures, leaving free cash flow of -£7.7 million. Cash and equivalents rose by £17.5 million over the year.

Related: NCNA income statement, NCNA balance sheet. See the NCNA stock overview for the latest quote and news.

NCNA cash flow FAQ

What is NuCana's free cash flow?

NuCana's free cash flow was -£7.7 million in fiscal 2025: -£7.5 million of operating cash flow minus £0.2 million of capital expenditures It was -£19.4 million a year earlier..

How much cash does NuCana generate from operations?

NuCana generated -£7.5 million of cash from operating activities in fiscal 2025.

How much does NuCana spend on capital expenditures?

NuCana spent £0.2 million on capital expenditures in fiscal 2025, compared with £0.3 million the year before.

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