NuCana plc (NCNA) Key Metrics
NCNA key metrics, 2016–2025
Fiscal year ended December 31, 2025 · British poundsNCNA returns How much profit the business earns on the capital it uses.
NCNA financial health Debt, liquidity and how easily interest is covered.
NCNA returns on capital
Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.
NCNA debt vs cash
Debt includes short- and long-term borrowings and, where reported, lease liabilities.
NCNA key metrics in British pounds
2016–2025| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Returns & profitability | ||||||||||
| Return on equity (ROE) | −193.9% | −182.3% | −103.5% | −61.5% | −49.2% | −37.7% | −29.5% | −15.8% | −38.9% | −21.9% |
| Return on invested capital (ROIC) | — | — | — | — | −416.5% | −231.2% | −248.3% | −307.0% | −293.7% | −221.6% |
| Return on assets (ROA) | −131.6% | −89.2% | −64.2% | −47.2% | −43.8% | −34.5% | −27.2% | −15.1% | −37.4% | −20.5% |
| Return on tangible assets | −106.2% | −151.1% | −107.6% | −57.3% | −54.0% | −29.8% | −32.3% | −16.5% | −24.5% | −23.4% |
| Financial health | ||||||||||
| Total debt | £676,000 | £190,000 | £396,000 | £639,000 | £371,000 | £645,000 | £806,000 | £0 | £0 | £0 |
| Cash & short-term investments | £24.3M | £6.7M | £17.2M | £41.9M | £60.3M | £87.4M | £52.0M | £77.0M | £86.7M | £20.0M |
| Net debt | −£23.6M | −£6.6M | −£16.8M | −£41.3M | −£59.9M | −£86.7M | −£51.2M | −£77.0M | −£86.7M | −£20.0M |
| Debt / equity | 0.03 | 0.03 | 0.03 | 0.02 | 0.01 | 0.01 | 0.01 | 0.00 | 0.00 | 0.00 |
| Debt / assets | 0.02 | 0.01 | 0.01 | 0.01 | 0.00 | 0.01 | 0.01 | 0.00 | 0.00 | 0.00 |
| Net debt / EBITDA | — | — | — | — | — | — | −71.25 | −207.47 | −446.92 | −197.92 |
| Current ratio | 5.60 | 1.42 | 1.97 | 2.84 | 6.11 | 12.49 | 10.54 | 15.02 | 32.22 | 13.09 |
| Quick ratio | 5.60 | 1.42 | 1.97 | 2.84 | 6.11 | 12.49 | 10.54 | 15.34 | 33.26 | 11.46 |
| Interest coverage | — | — | -29.7 | -4.0 | -9.6 | -5.4 | -27.0 | — | — | — |
| Working capital | £22.1M | £3.6M | £12.3M | £35.6M | £59.9M | £93.7M | £59.0M | £78.0M | £91.1M | £23.8M |
| Invested capital | £752,000 | −£605,000 | −£1.9M | −£2.8M | £5.7M | £12.5M | £12.4M | £4.6M | £6.7M | £5.3M |
| Tangible asset value | £22.1M | £3.8M | £12.8M | £36.1M | £63.1M | £94.5M | £59.6M | £78.5M | £91.5M | £23.9M |
| Net current asset value | £21.4M | £3.4M | £12.1M | £35.2M | £59.7M | £93.2M | £58.4M | £78.0M | £91.0M | £23.8M |
| Capital allocation | ||||||||||
| Dividends paid | — | — | — | — | — | — | £0 | £0 | £0 | £0 |
| Share buybacks (net) | — | — | — | — | — | — | £0 | £0 | £0 | £0 |
| Capex / revenue | — | — | — | — | — | — | — | — | 386.9% | — |
| Capex / depreciation | 0.70 | 0.56 | 0.83 | 0.71 | 1.13 | 1.83 | 1.76 | 4.38 | 5.64 | 5.49 |
| Stock-based compensation / revenue | — | — | — | — | — | — | — | — | 4,145.2% | — |
| R&D / revenue | — | — | — | — | — | — | — | — | 6,244.9% | — |
| SG&A / revenue | — | — | — | — | — | — | — | — | 1,615.9% | — |
| Efficiency | ||||||||||
| Days sales outstanding | — | — | — | — | — | — | — | — | 4,759.2 | — |
| Days payables outstanding | 2,197.5 | — | — | — | — | — | — | — | — | — |
| Receivables turnover | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.08 | 0.00 |
| Payables turnover | 0.17 | — | — | — | — | — | 0.00 | 0.00 | 0.00 | 0.00 |
| Asset turnover | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Average receivables | £3.3M | £5.2M | £6.4M | £7.6M | £9.4M | £9.9M | £6.9M | £4.8M | £3.7M | £2.1M |
| Average payables | £1.6M | £3.0M | £4.1M | £3.3M | £2.0M | £2.3M | £2.4M | £1.8M | £924,000 | £617,500 |
| Average inventory | — | — | — | — | −£12,900 | −£13,820 | −£906,596 | −£2.4M | £76,000 | −£5.9M |
| Intangibles / total assets | 7.4% | 14.9% | 7.7% | 4.1% | 3.1% | 4.4% | 5.6% | 3.6% | 2.0% | 5.1% |
Computed from NCNA's annual financial statements (latest annual report filed March 19, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in British pounds; data from EODHD. Averages use the opening and closing balance of each year.
NCNA valuation and financial ratios
NuCana earned a return on equity of −193.9% in fiscal 2025. It ended the year with £0.7 million of debt and £24.3 million in cash and short-term investments, a net cash position of £23.6 million.
See the NCNA income statement, the NCNA chart for price history, or the NCNA stock overview for the latest quote and news.
NCNA key metrics FAQ
What is NuCana's return on equity?
NuCana's return on equity (ROE) was −193.9% in fiscal 2025: net income of -£29.4 million on average shareholders' equity of £15.1 million.
How much debt does NuCana have?
NuCana had total debt of £0.7 million at the end of fiscal 2025, a debt-to-equity ratio of 0.03 and more cash than debt.
What is NuCana's current ratio?
NuCana's current ratio was 5.60 at the end of fiscal 2025: current assets were 5.60 times current liabilities.