Nurix Therapeutics, Inc. (NRIX) AI Stock Analysis
NRIX AI stock analysis summary
AI ResearchNurix Therapeutics, Inc. (NRIX) is a biopharmaceutical company focused on developing targeted small molecule therapies for cancer and immune disorders. The company generated $701.9M in trailing twelve-month revenue, recording an operating margin of 83.1% and a profit margin of 42.0%. Its balance sheet is anchored by $1.05B in cash and short-term investments alongside a net cash position of $982.9M as of August 31, 2026.
- Market cap
- $2.67B
- Revenue (TTM)
- $701.9M
- P/E
- 10.0x
- 1Y return
- 143.5% S&P 500 16.8%
- Avg. target
- $34.50 41.3% vs last close
Bull case
- The balance sheet provides substantial financial flexibility with $1.05B in cash and short-term investments against total debt of $65.3M.
- Trailing twelve-month revenue reached $701.9M, supported by latest quarterly revenue growth of 8426.3%.
- Analyst sentiment is positive with 8 Strong Buy ratings and a mean price target of $34.50.
Bear case
- In FY2025, Nurix Therapeutics reported a net income of -$264.5M and free cash flow of -$263.5M.
- Consensus estimates from 3 analysts indicate revenue growth of -83.5% to $123.2M for the next fiscal year.
- The 5-year stock return stands at -15.3%, accompanied by a 160.7% dilution in share count over 5 years.
What Nurix Therapeutics does
Nurix Therapeutics, Inc. is a biopharmaceutical company focused on discovering, developing, and commercializing small molecule therapies that target critical pathways in disease progression. Its clinical pipeline features NX-2127 and NX-5948, which are orally available Bruton's tyrosine kinase (BTK) degraders designed to address B-cell malignancies and autoimmune diseases. The company is also advancing CBL-B inhibitors, including NX-1607 for immuno-oncology applications, NX-0255 for ex vivo use in adoptive T-cell therapy, and DeTIL-0255 in Phase 1 clinical trials for gynecologic cancers such as ovarian, endometrial, and cervical cancer. Nurix maintains strategic collaborations with industry partners including Gilead Sciences, Inc. and Sanofi S.A.
Growth and profitability
Nurix Therapeutics expanded annual revenue from $29.8M in FY2021 to $38.6M in FY2022 and $77.0M in FY2023. Annual revenue dipped to $54.5M in FY2024 before rising 54.0% to $84.0M in FY2025, reflecting a 5-year revenue CAGR of 36.3%. In FY2025, operating margin was -340.2%, net income was -$264.5M, and eps was -$3.04. Over the trailing twelve months ended August 31, 2026, performance shifted significantly to revenue of $701.9M, eps of $2.43, and an operating margin of 83.1%, driven by latest quarterly revenue growth of 8426.3%.
Balance sheet and cash flow
As of August 31, 2026, Nurix Therapeutics held $1.05B in cash and short-term investments against total debt of $65.3M, resulting in net cash of $982.9M. Total assets reached $1.20B, shareholders' equity stood at $968.3M, and the current ratio was 8.44 with a debt-to-equity ratio of 0.07. In FY2025, operating cash flow was -$249.5M, free cash flow was -$263.5M, and capital expenditures were $14.0M. The company's 5-year share count change was 160.7%.
Valuation and performance
Nurix Therapeutics trades at a trailing price-to-earnings multiple of 10.0x, below the 24.6x median of its US-listed Healthcare peers. Its price-to-sales multiple is 3.8x compared to the peer median of 4.1x, while enterprise value to revenue stands at 56.9x. The company carries a market cap of $2.67B and an enterprise value of $2.09B. Over the past year, the stock returned 143.5%, outperforming the 16.8% return of the S&P 500. Over 5 years, the stock returned -15.3% against an 83.0% gain for the S&P 500.
What analysts expect
Wall Street analysts have issued 8 Strong Buy, 5 Buy, and 1 Hold ratings on the stock. The mean price target is $34.50, implying an upside of 41.3% from the last close of $24.42. For the fiscal year ending November 30, 2026, consensus estimates project revenue of $744.8M and eps of $3.02, reflecting eps growth of 199.0%. For the next fiscal year, 3 analysts project revenue of $123.2M and eps of -$1.28. Over the last 4 quarters, the company recorded 3 eps beats.
Key risks and what to watch
- A short interest of 16.3% of float and a beta of 1.82 highlight high price volatility.
- Research and development expense reached $308.2M in FY2025, contributing to operating cash flow of -$249.5M.
- Estimates from 3 analysts project an eps growth estimate of -142.2% for the next fiscal year.
AI-generated research summary. Written with AI from Quotelinks data as of October 16, 2026 and checked so every figure matches that data. For information only, not investment advice. Disclaimer
About this NRIX AI stock analysis
This page is an AI-written research summary of Nurix Therapeutics, Inc. (NRIX). The text was generated on October 30, 2026 from Quotelinks data as of October 16, 2026 (company profile, annual results, latest balance sheet, valuation, price performance and analyst estimates). An automatic check rejects any draft that contains a figure not found in that data. It is not investment advice; verify figures on the linked tabs before making decisions.
Related: NRIX income statement, NRIX balance sheet, NRIX key metrics, NRIX analyst forecast, NRIX chart. See the NRIX stock overview for the latest quote and news.
NRIX AI stock analysis FAQ
What was Nurix Therapeutics' revenue growth in the latest quarter?
In the quarter ended August 31, 2026, quarterly revenue grew by 8426.3% year-over-year, lifting trailing twelve-month revenue to $701.9M.
How strong is Nurix Therapeutics' cash balance?
As of August 31, 2026, the company held $1.05B in cash and short-term investments with total debt of $65.3M, resulting in net cash of $982.9M and a current ratio of 8.44.
What are analysts forecasting for NRIX stock?
Wall Street analysts have posted 8 Strong Buy, 5 Buy, and 1 Hold ratings, with an average price target of $34.50 compared to the last close of $24.42.
How does Nurix Therapeutics' valuation compare to peers?
NRIX trades at a trailing P/E of 10.0x and a price-to-sales of 3.8x, compared to the US-listed Healthcare peer medians of 24.6x and 4.1x, respectively.