Adaptive Biotechnologies Corporation (ADPT) AI Stock Analysis

NASDAQ: ADPTAI research summary: business, growth, valuation, analysts, bull and bear case.

ADPT AI stock analysis summary

AI Research

Adaptive Biotechnologies Corporation (ADPT) is a commercial-stage immune medicine company developing diagnostics and immunosequencing platforms such as clonoSEQ and immunoSEQ. Revenue reached $277.0M in FY2025 with gross margin improving to 74.2%, up from 59.7% in FY2024. While annual net losses have narrowed from -$225.2M in FY2023 to -$59.5M in FY2025, operating cash flow and net earnings remain negative.

Market cap
$3.83B
Revenue (TTM)
$308.1M
P/E
—
1Y return
39.1%
S&P 500 16.8%
Avg. target
$29.81
24.1% vs last close

Bull case

  • FY2025 revenue surged 54.8% to $277.0M, driven by accelerating adoption of diagnostic products.
  • Gross margins expanded to 74.2% in FY2025, helping narrow annual net losses from -$225.2M in FY2023 to -$59.5M.
  • Wall Street maintains 8 positive ratings against 1 hold, with a mean price target of $29.81 pointing to 24.1% upside.

Bear case

  • The company remains unprofitable, recording a trailing twelve-month net margin of -20.7% and -$46.0M in FY2025 operating cash flow.
  • Valuation is elevated relative to peers, with a price-to-sales ratio of 12.4x compared to the US-listed Healthcare median of 4.1x.
  • Total debt of $410.5M exceeds cash and short-term investments of $344.3M, leaving net debt at $66.2M.

What Adaptive Biotechnologies does

Adaptive Biotechnologies Corporation is a commercial-stage company focused on immune medicine platforms to diagnose and treat diseases. Its core offerings include immunoSEQ, an immunosequencing platform that supports translational research and discovery of diagnostic signals. The company's flagship clinical diagnostic product, clonoSEQ, is a CLIA-validated laboratory developed test used to detect and monitor minimal residual disease in patients with lymphoid cancers such as multiple myeloma, acute lymphoblastic leukemia, and chronic lymphocytic leukemia. The company also maintains a clinical pipeline across cancer and autoimmune disorders, and collaborates with industry partners like Genentech, Inc.

Growth and profitability

Adaptive Biotechnologies grew annual revenue from $154.3M in FY2021 to $277.0M in FY2025, delivering a 5-year revenue CAGR of 23.0%. Revenue increased 54.8% in FY2025 after expanding 5.1% in FY2024 and declining 8.1% in FY2023. Gross margin reached 74.2% in FY2025, up from 55.6% in FY2023. Operating margin improved to -20.6% in FY2025 compared to -133.3% in FY2023, while net loss narrowed to -$59.5M from -$225.2M. Over the trailing twelve months ended June 30, 2026, revenue stood at $308.1M with quarterly revenue growing 21.5% year-over-year. TTM operating margin was -22.0% and EPS was -$0.41.

ADPT income statement →

Balance sheet and cash flow

As of June 30, 2026, the company held $344.3M in cash and short-term investments against total debt of $410.5M, resulting in net debt of $66.2M. Shareholders' equity was $142.9M, with a debt-to-equity ratio of 2.87 and a current ratio of 4.79. Operating cash flow in FY2025 was -$46.0M, an improvement from -$95.2M in FY2024. Capital expenditures totaled $3.0M in FY2025, leading to free cash flow of -$48.9M. The share count increased 11.7% over 5 years.

ADPT balance sheet →

Valuation and performance

ADPT trades at an enterprise value of $4.52B and a market cap of $3.83B. Its price-to-sales ratio is 12.4x and EV-to-revenue is 14.7x, compared to the median price-to-sales of 4.1x for its US-listed Healthcare peers. Its price-to-book multiple is 31.1x. Over the past year, ADPT returned 39.1%, outperforming the S&P 500's 16.8% return. Over 5 years, the stock returned -28.3% compared to an 83.0% gain for the benchmark.

ADPT key metrics →

What analysts expect

Wall Street coverage includes 6 Strong Buy, 2 Buy, and 1 Hold ratings. The mean price target is $29.81, representing 24.1% upside over the last close of $24.02. Consensus expectations project FY2026 revenue of $293.4M with EPS of -$0.54, followed by FY2027 revenue of $359.2M and EPS of -$0.18. Adaptive Biotechnologies beat EPS expectations in each of the last 4 quarters. The next earnings date is November 4, 2026.

ADPT forecast and price target →

Key risks and what to watch

  • Stock price volatility is significant, reflected by a beta of 2.10 and a 52-week trading range spanning from $12.00 to $30.74.
  • Short interest stands at 9.4% of float, indicating substantial market skepticism.
  • Ongoing negative free cash flow of -$48.9M in FY2025 could pressure the balance sheet if top-line momentum slows.
  • Dilution remains a factor, with total share count expanding 11.7% over the last 5 years.

AI-generated research summary. Written with AI from Quotelinks data as of October 16, 2026 and checked so every figure matches that data. For information only, not investment advice. Disclaimer

About this ADPT AI stock analysis

This page is an AI-written research summary of Adaptive Biotechnologies Corporation (ADPT). The text was generated on October 30, 2026 from Quotelinks data as of October 16, 2026 (company profile, annual results, latest balance sheet, valuation, price performance and analyst estimates). An automatic check rejects any draft that contains a figure not found in that data. It is not investment advice; verify figures on the linked tabs before making decisions.

Related: ADPT income statement, ADPT balance sheet, ADPT key metrics, ADPT analyst forecast, ADPT chart. See the ADPT stock overview for the latest quote and news.

ADPT AI stock analysis FAQ

What does Adaptive Biotechnologies Corporation do?

Adaptive Biotechnologies Corporation provides immune medicine diagnostics and sequencing platforms. Key offerings include immunoSEQ for research and clonoSEQ for detecting minimal residual disease in lymphoid cancers.

Is Adaptive Biotechnologies profitable?

No, the company is not yet profitable. It posted an annual net loss of -$59.5M in FY2025 and an EPS of -$0.41 over the trailing twelve months ended June 30, 2026.

Does ADPT pay a dividend?

No, Adaptive Biotechnologies does not pay a dividend.

When does Adaptive Biotechnologies report its next earnings?

The company's next scheduled earnings release date is November 4, 2026.

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