Lyra Therapeutics, Inc. (LYRA) Ownership

OTC Pink: LYRATop holders, insider trades and short interest.

LYRA ownership summary

as of October 21, 2026
Institutions
6.6%
of shares outstanding
Insiders
0.62%
of shares outstanding
Shares outstanding
1.8M
Float
440K
shares available to trade
Short interest
2.82%
17K shares short
Days to cover
0.65
short interest down 70.7% vs prior month
  • Institutions 6.64%
  • Insiders 0.62%
  • Other investors 92.74%

LYRA top institutional holders

20 largest
Lyra Therapeutics, Inc. top institutional holders
#Holder% of sharesSharesValueChangeReported
1Sabby Management LLC5.86%104K$19,771−71,099 (−40.6%)March 31, 2026
2EverSource Wealth Advisors, LLC0.00%——−338 (−100.0%)March 31, 2026
3Bryn Mawr Trust Company0.00%——−20 (−100.0%)March 31, 2026
4DRW Securities, LLC0.00%——−16,812 (−100.0%)March 31, 2026
5Ikarian Capital, LLC0.00%——−21,161 (−100.0%)March 31, 2026
6BlackRock Inc0.00%——−2,394 (−100.0%)March 31, 2026
7Royal Bank of Canada0.00%——−1,953 (−100.0%)March 31, 2026
8Tower Research Capital LLC0.00%——−2,191 (−100.0%)March 31, 2026
9Citigroup Inc0.00%——−3 (−100.0%)March 31, 2026
10Global Retirement Partners, LLC.0.00%——−15 (−100.0%)June 30, 2026
11UBS Group AG0.00%——−675 (−100.0%)March 31, 2026
12BNP Paribas Arbitrage, SA0.00%——−16 (−100.0%)March 31, 2026
13Morgan Stanley - Brokerage Accounts0.00%——−334 (−100.0%)March 31, 2026
14Artia Global Partners LP0.00%——−8,756 (−100.0%)March 31, 2026
15Geode Capital Management, LLC0.00%——−12,249 (−100.0%)March 31, 2026
16JONES FINANCIAL COMPANIES LLLP0.00%——−210 (−100.0%)March 31, 2026
17JPMorgan Chase & Co0.00%——−27 (−100.0%)March 31, 2026
18SBI Securities Co Ltd0.00%——−80 (−100.0%)March 31, 2026
19Advisor Group Holdings, Inc.0.00%——−22 (−100.0%)March 31, 2026
20IFP Advisors, LLC0.00%——−1 (−100.0%)March 31, 2026

Value at the latest close. Change = shares bought or sold in the latest quarterly filing (13F). In the top 20, 0 holders added 0 shares and 20 cut 138K.

LYRA top mutual fund and ETF holders

2 largest
Lyra Therapeutics, Inc. top fund holders
#Holder% of sharesSharesValueChangeReported
1Extended Equity Market Fund B0.09%1,633$310—December 31, 2025
2Extended Equity Market Fund E0.09%1,633$310—December 31, 2025

Funds report holdings monthly or quarterly; dates differ by fund.

LYRA insider transactions

latest 10
Lyra Therapeutics, Inc. insider transactions
DateNameTransactionPriceSharesValue
2026-01-06Jason CavalierSell$3.36769$2,584
2026-01-06Maria PalasisSell$3.361,702$5,719
2025-11-13Perceptive Advisors LlcSell$3.9031,810$124,059
2025-11-12Perceptive Advisors LlcSell$4.068,745$35,505
2025-11-11Perceptive Advisors LlcSell$4.315,320$22,929
2025-11-10Perceptive Advisors LlcSell$4.5418,502$83,999
2025-11-07Perceptive Advisors LlcSell$4.7519,739$93,760
2025-11-06Perceptive Advisors LlcSell$5.1832,149$166,532
2025-07-10Jason CavalierSell$8.91684$6,094
2025-07-10Maria PalasisSell$8.911,565$13,944

Reported trades by company officers, directors and other filers (including disclosures by members of Congress where EODHD lists them). "—" where the filing gives no share count.

LYRA shares outstanding

Shares outstanding

Year-end shares outstanding, adjusted for splits.

Who owns LYRA

Institutional investors own 6.6% of Lyra Therapeutics's shares and insiders 0.62%. The largest holder is Sabby Management LLC with 5.86% of the shares (104K), as of March 31, 2026. Among the top 20 institutions, 0 added shares and 20 reduced their stake in the latest filings. Short interest is 2.82% of the float, or 0.65 days of average trading volume. The share count rose 89.8% since 2019.

Related: LYRA analyst forecast, LYRA key metrics. See the LYRA stock overview for the latest quote and news.

LYRA ownership FAQ

Who owns the most Lyra Therapeutics stock?

The largest shareholders of Lyra Therapeutics are Sabby Management LLC (5.86%), EverSource Wealth Advisors, LLC (0.00%), Bryn Mawr Trust Company (0.00%), DRW Securities, LLC (0.00%), Ikarian Capital, LLC (0.00%).

What percentage of Lyra Therapeutics is owned by institutions?

Institutions hold 6.6% of Lyra Therapeutics's shares outstanding; insiders hold 0.62%.

Which funds own Lyra Therapeutics?

The largest fund holders of Lyra Therapeutics are Extended Equity Market Fund B (0.09%), Extended Equity Market Fund E (0.09%).

What is Lyra Therapeutics's short interest?

17K shares of Lyra Therapeutics were sold short, 2.82% of the float; at the average daily volume it would take 0.65 days to cover.

Are insiders buying or selling Lyra Therapeutics?

Of the latest 10 reported insider transactions in Lyra Therapeutics (since July 10, 2025), 0 were purchases and 10 were sales.

How many shares of Lyra Therapeutics are outstanding?

Lyra Therapeutics has 1.8M shares outstanding, of which 440K are in the public float.

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