X4 Pharmaceuticals, Inc. (XFOR) Key Metrics

NASDAQ: XFORValuation, returns, debt and efficiency ratios over 10 years.

XFOR valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$256.8M
Enterprise value
$177.6M
P/E (TTM)
129.5
Forward P/E
—
PEG ratio
—
Price / sales
16.2
Price / book
2.0
EV / EBITDA
1.1
Dividend yield
—
Beta
0.46

XFOR key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

XFOR returns How much profit the business earns on the capital it uses.

Return on equity+26.3 pts
−76.0%
2025 · hover or tap a bar for each year
2017: −161.4%2018: −82.9% (+78.5 pts)2019: −70.0% (+12.9 pts)2020: −61.5% (+8.5 pts)2021: −129.3% (−67.8 pts)2022: −135.6% (−6.3 pts)2023: −161.7% (−26.1 pts)2024: −102.3% (+59.4 pts)2025: −76.0% (+26.3 pts)
20162025
Return on assets−10.8 pts
−36.3%
2025 · hover or tap a bar for each year
2016: −268.5% (−129.5 pts)2017: −76.2% (+192.2 pts)2018: −56.8% (+19.5 pts)2019: −53.7% (+3.1 pts)2020: −43.8% (+9.9 pts)2021: −73.9% (−30.1 pts)2022: −68.8% (+5.1 pts)2023: −66.8% (+2.0 pts)2024: −25.5% (+41.3 pts)2025: −36.3% (−10.8 pts)
20162025
Free cash flow margin
−252.4%
2025 · hover or tap a bar for each year
2018: −726.3%2025: −252.4%
20162025
Asset turnover+823.1%
0.16
2025 · hover or tap a bar for each year
2016: 0.002017: 0.002018: 0.062019: 0.03 (−48.9%)2020: 0.02 (−30.6%)2021: 0.00 (−100.0%)2022: 0.002023: 0.002024: 0.022025: 0.16 (+823.1%)
20162025

XFOR valuation history

Fiscal year-endToday10-year median

XFOR returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

XFOR debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

XFOR cash returned to shareholders

DividendsBuybacksFree cash flow

XFOR price vs earnings per share

Share price at year-endEPS (right axis)

XFOR key metrics

2016–2025
X4 Pharmaceuticals, Inc. key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$169.2M—————————
Enterprise value−$6.5M—————————
Price / sales4.8—————————
Price / book0.9—————————
EV / sales-0.2—————————
Earnings yield−46.8%—————————
Free cash flow yield−52.4%—————————
Share price at fiscal year-end$4.00$22.02$25.17$29.79$68.70$192.90$321.00$417.60$2,296.80—
Per share
Revenue per share$0.83—————————
Earnings per share−$1.87—————————
Operating cash flow per share−$2.02—————————
Free cash flow per share−$2.10—————————
Cash per share$5.98—————————
Book value per share$4.40—————————
Tangible book value per share$3.78—————————
Capex per share$0.07—————————
Debt per share$1.83—————————
Shares outstanding42.3M—————————
Returns & profitability
Return on equity (ROE)−76.0%−102.3%−161.7%−135.6%−129.3%−61.5%−70.0%−82.9%−161.4%—
Return on invested capital (ROIC)————−217.7%−162.5%−280.4%———
Return on assets (ROA)−36.3%−25.5%−66.8%−68.8%−73.9%−43.8%−53.7%−56.8%−76.2%−268.5%
Return on tangible assets−30.0%−31.4%−77.9%−67.9%−88.9%−64.9%−39.5%−92.4%−41.7%−302.1%
Free cash flow margin−252.4%——————−726.3%——
Financial health
Total debt$77.3M$78.1M$58.3M$38.4M$39.8M$38.4M$22.9M$9.6M$12.2M$15.3M
Cash & short-term investments$253.0M$102.1M$114.2M$121.7M$81.8M$79.0M$126.2M$30.8M$76.8M$3.0M
Net debt−$175.7M−$24.0M−$55.9M−$83.3M−$42.0M−$40.5M−$103.3M−$21.2M−$64.6M$12.2M
Debt / equity0.413.531.140.520.620.530.180.440.21—
Debt / assets0.270.530.400.250.340.310.140.270.152.01
Current ratio10.163.415.345.766.276.9713.686.507.450.47
Quick ratio9.983.335.345.766.326.9713.686.507.410.37
Interest coverage-9.8-4.2-18.6-21.9-20.7-22.3-21.8-40.4-17.4-9.7
Working capital$235.8M$79.3M$99.2M$106.4M$73.9M$71.4M$119.8M$29.7M$68.8M−$6.3M
Invested capital$10.6M−$1.8M−$4.8M−$9.2M$22.4M$32.3M$25.9M$427,000−$5.8M−$4.5M
Tangible asset value$159.7M−$5.2M$33.7M$56.7M$47.1M$45.7M$102.1M$21.6M$58.7M−$16.7M
Net current asset value$157.4M−$12.1M$25.9M$47.1M$35.1M$33.2M$97.8M$20.7M$57.0M−$18.6M
Graham net-net per share$3.58—————————
Capital allocation
Dividends paid———$12$13.9M$12.4M$20.0M—$45.7M—
Share buybacks (net)——$0$12$2.0M$277,000$0$1.1M$197,000$87,000
Capex / revenue8.5%286.5%———45.4%5.8%1.0%——
Capex / depreciation2.359.200.140.200.331.111.690.330.220.24
Stock-based compensation / revenue12.2%320.8%———180.9%68.3%160.6%——
R&D / revenue205.7%3,192.9%———1,397.7%1,005.4%581.3%——
SG&A / revenue123.9%2,405.9%———698.1%588.0%525.9%——
Efficiency
Days sales outstanding11.9162.2———177.3295.5232.9——
Days of inventory on hand212.8645.0——-144.1———1,498.41,516.0
Days payables outstanding417.64,022.81,529.11,103.8716.4776.3715.14,319.83,311.21,258.0
Cash conversion cycle (days)-192.9-3,215.6———-599.0-419.6-4,086.8——
Receivables turnover30.762.250.000.000.002.061.241.570.000.00
Payables turnover0.870.090.240.330.510.470.510.080.110.29
Inventory turnover1.720.57——————0.240.24
Asset turnover0.160.020.000.000.000.020.030.060.000.00
Average receivables$1.1M$1.1M$857,000$949,500$832,000$1.5M$2.4M$2.2M$1.5M$1.4M
Average payables$7.2M$8.8M$8.4M$6.0M$3.7M$2.6M$1.3M$1.2M$1.8M$1.0M
Average inventory$3.6M$1.4M$0—−$747,000———$800,500$1.2M
Intangibles / total assets9.2%18.7%11.8%11.2%14.8%22.1%16.9%0.0%0.0%0.0%

Computed from XFOR's annual financial statements (latest annual report filed March 17, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

XFOR valuation and financial ratios

Based on the latest twelve months, the trailing P/E is 129.5. X4 Pharmaceuticals earned a return on equity of −76.0% in fiscal 2025. It ended the year with $77.3 million of debt and $253.0 million in cash and short-term investments, a net cash position of $175.7 million.

See the XFOR income statement, the XFOR chart for price history, or the XFOR stock overview for the latest quote and news.

XFOR key metrics FAQ

What is X4 Pharmaceuticals's P/E ratio?

X4 Pharmaceuticals's trailing P/E ratio is 129.5 based on the last twelve months of earnings (as of October 18, 2026). At the end of fiscal 2025 it was —.

What is X4 Pharmaceuticals's return on equity?

X4 Pharmaceuticals's return on equity (ROE) was −76.0% in fiscal 2025: net income of -$79.2 million on average shareholders' equity of $104.2 million.

How much debt does X4 Pharmaceuticals have?

X4 Pharmaceuticals had total debt of $77.3 million at the end of fiscal 2025, a debt-to-equity ratio of 0.41 and more cash than debt.

What is X4 Pharmaceuticals's free cash flow yield?

X4 Pharmaceuticals generated -$88.6 million of free cash flow in fiscal 2025, a free cash flow yield of −52.4% on its market value at year-end ($169.2 million).

What is X4 Pharmaceuticals's current ratio?

X4 Pharmaceuticals's current ratio was 10.16 at the end of fiscal 2025: current assets were 10.16 times current liabilities.

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