Xenetic Biosciences, Inc. (XBIO) Key Metrics

NASDAQ: XBIOValuation, returns, debt and efficiency ratios over 10 years.

XBIO valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$4.7M
Enterprise value
−$613,814
P/E (TTM)
—
Forward P/E
—
PEG ratio
—
Price / sales
1.4
10-yr median 2.4
Price / book
1.0
10-yr median 0.6
EV / EBITDA
1.0
Dividend yield
—
Beta
2.20

XBIO key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

XBIO valuation Price multiples at each fiscal year-end price.

Price / sales−49.6%
1.2
2025 · hover or tap a bar for each year
2020: 29.82021: 11.4 (−61.7%)2022: 2.4 (−79.2%)2023: 2.1 (−12.6%)2024: 2.5 (+18.5%)2025: 1.2 (−49.6%)
20162025
Price / book−51.2%
0.5
2025 · hover or tap a bar for each year
2020: 1.12021: 0.7 (−32.5%)2022: 0.3 (−58.8%)2023: 0.5 (+81.1%)2024: 1.0 (+90.2%)2025: 0.5 (−51.2%)
20162025
Free cash flow yield−16.1 pts
−61.9%
2025 · hover or tap a bar for each year
2020: −32.7%2021: −35.7% (−3.0 pts)2022: −126.9% (−91.2 pts)2023: −78.0% (+48.9 pts)2024: −45.8% (+32.2 pts)2025: −61.9% (−16.1 pts)
20162025

XBIO valuation history

Fiscal year-endToday10-year median

XBIO returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

XBIO debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

XBIO cash returned to shareholders

DividendsBuybacksFree cash flow

XBIO price vs earnings per share

Share price at year-endEPS (right axis)

XBIO key metrics

2016–2025
Xenetic Biosciences, Inc. key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$3.7M$6.1M$5.3M$4.1M$13.3M$13.0M————
Enterprise value−$4.2M−$15,625−$3.7M−$9.0M−$5.0M$1.6M————
Price / sales1.22.52.12.411.429.8————
Price / book0.51.00.50.30.71.1————
EV / sales-1.4-0.0-1.5-5.3-4.33.6————
Earnings yield−72.6%−64.4%−78.4%−161.6%−42.6%−83.5%————
Free cash flow yield−61.9%−45.8%−78.0%−126.9%−35.7%−32.7%————
Shareholder yield (dividends + buybacks)———0.0%—0.0%————
Share price at fiscal year-end$2.17$3.99$3.45$2.85$12.90$20.40$14.40$196.80$230.22$516.00
Per share
Revenue per share$1.75$1.62$1.66$1.20$1.13$0.68————
Earnings per share−$1.58−$2.57−$2.71−$4.61−$5.49−$17.04————
Operating cash flow per share−$1.34−$1.83−$2.69−$3.27−$4.61−$6.68————
Free cash flow per share−$1.34−$1.83−$2.69−$3.62−$4.61−$6.68————
Cash per share$4.63$4.00$5.88$9.21$17.75$18.03————
Book value per share$4.35$3.90$6.41$9.59$17.89$19.11————
Tangible book value per share$4.35$3.90$6.41$9.59$17.89$19.11————
Capex per share$0.00$0.00$0.00$0.35$0.00$0.00————
Debt per share————$0.03$0.10————
Shares outstanding1.7M1.5M1.5M1.4M1.0M639K————
Change in shares outstanding+10.4%+0.9%+7.4%+38.4%+60.8%—————
Returns & profitability
Return on equity (ROE)−40.0%−50.1%−35.3%−40.9%−36.9%−74.0%−94.2%−60.3%−23.6%−475.9%
Return on invested capital (ROIC)——−523.7%—−978.7%−289.2%−125.6%−63.5%−27.0%−394.6%
Return on assets (ROA)−35.1%−45.2%−32.7%−37.9%−34.2%−62.7%−71.0%−43.5%−17.9%−286.2%
Return on tangible assets−32.1%−57.4%−39.0%−44.5%−28.5%−82.7%−417.4%−383.3%−54.2%−641.7%
Free cash flow margin−76.8%−112.7%−162.0%−301.5%−408.2%−976.6%——19.6%−293.5%
Financial health
Total debt————$27,043$62,525$20,042———
Cash & short-term investments$7.9M$6.2M$9.0M$13.1M$18.2M$11.5M$10.4M$571,605$5.5M$4.0M
Net debt−$7.9M−$6.2M−$9.0M−$13.1M−$18.2M−$11.5M−$10.3M−$571,605−$5.5M−$4.0M
Debt / equity————0.000.010.00———
Debt / assets————0.000.000.00———
Current ratio8.327.3711.8412.7213.1813.207.840.753.034.47
Quick ratio8.327.3711.8412.7213.1813.207.840.753.034.47
Interest coverage———-40.6-56.6-0.8-115.3-301.5—-65.0
Working capital$7.1M$5.7M$8.8M$12.6M$17.3M$11.4M$9.7M−$405,817$3.9M$6.5M
Invested capital−$487,810−$158,388$812,595$549,869$177,270$750,497$6.9M$9.3M$8.8M$12.1M
Tangible asset value$7.4M$6.0M$9.8M$13.6M$18.4M$12.2M−$1.3M−$2.6M$1.8M$3.6M
Net current asset value$7.1M$5.7M$8.8M$12.6M$17.3M$11.4M$6.8M−$3.3M$1.0M$3.5M
Graham net-net per share$4.06$3.42$5.35$8.45$16.37$17.11————
Capital allocation
Dividends paid—————————$39.5M
Share buybacks (net)———$0—$0$0$0—$0
Capex / revenue0.0%0.0%0.0%29.3%0.0%0.0%0.0%—0.1%0.6%
Capex / operating cash flow————————0.6%—
Capex / depreciation—0.00—18.490.000.000.000.000.390.46
Stock-based compensation / revenue2.2%6.9%11.1%30.0%35.4%107.3%5,001.3%—25.3%70.1%
R&D / revenue103.0%131.5%137.6%279.5%272.6%396.3%28,649.6%—53.5%1,457.9%
SG&A / revenue92.2%136.6%140.2%214.1%322.6%778.2%27,722.8%—91.5%223.1%
Efficiency
Days sales outstanding—————417.7———365.0
Days of inventory on hand—————————0.0
Days payables outstanding———4,385.43,548.3——19,843.92,096.813,996.7
Cash conversion cycle (days)—————————-13,631.7
Receivables turnover—————0.87———1.00
Payables turnover0.000.000.000.080.100.000.000.020.170.03
Inventory turnover—————————36,449.00
Asset turnover0.390.290.200.100.070.030.000.000.380.16
Average receivables—————$500,000———$3.0M
Average payables$270,862$262,224$264,096$324,915$344,933$629,262$932,638$860,463$896,841$1.4M
Average inventory—————————$1
Intangibles / total assets0.0%0.0%0.0%0.0%0.0%0.0%85.8%86.8%65.4%59.7%

Computed from XBIO's annual financial statements (latest annual report filed March 12, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

XBIO valuation and financial ratios

Xenetic Biosciences earned a return on equity of −40.0% in fiscal 2025.

See the XBIO income statement, the XBIO chart for price history, or the XBIO stock overview for the latest quote and news.

XBIO key metrics FAQ

What is Xenetic Biosciences's return on equity?

Xenetic Biosciences's return on equity (ROE) was −40.0% in fiscal 2025: net income of -$2.7 million on average shareholders' equity of $6.7 million.

What is Xenetic Biosciences's free cash flow yield?

Xenetic Biosciences generated -$2.3 million of free cash flow in fiscal 2025, a free cash flow yield of −61.9% on its market value at year-end ($3.7 million).

What is Xenetic Biosciences's current ratio?

Xenetic Biosciences's current ratio was 8.32 at the end of fiscal 2025: current assets were 8.32 times current liabilities.

Biotechnology key metrics