Talphera, Inc. (TLPH) Key Metrics

NASDAQ: TLPHValuation, returns, debt and efficiency ratios over 10 years.

TLPH valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$56.1M
Enterprise value
$43.4M
P/E (TTM)
—
Forward P/E
1.0
PEG ratio
—
Price / sales
—
Price / book
4.2
10-yr median 1.7
EV / EBITDA
0.1
Dividend yield
—
Beta
0.68

TLPH key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

TLPH valuation Price multiples at each fiscal year-end price.

Price / book+69.0%
2.8
2025 · hover or tap a bar for each year
2023: 0.72024: 1.7 (+124.5%)2025: 2.8 (+69.0%)
20162025
Free cash flow yield+70.9 pts
−23.5%
2025 · hover or tap a bar for each year
2023: −166.7%2024: −94.4% (+72.3 pts)2025: −23.5% (+70.9 pts)
20162025

TLPH valuation history

Fiscal year-endToday10-year median

TLPH returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

TLPH debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

TLPH cash returned to shareholders

DividendsBuybacksFree cash flow

TLPH price vs earnings per share

Share price at year-endEPS (right axis)

TLPH key metrics

2016–2025
Talphera, Inc. key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$48.3M$13.4M$10.6M———————
Enterprise value$34.5M$11.1M$1.2M———————
Price / sales——16.2———————
Price / book2.81.70.7———————
EV / sales——1.8———————
Earnings yield−29.6%−96.8%−174.3%———————
Free cash flow yield−23.5%−94.4%−166.7%———————
Shareholder yield (dividends + buybacks)——0.2%———————
Share price at fiscal year-end$1.14$0.52$0.74$2.26$11.20$24.80$42.20$46.20$40.60$52.00
Per share
Revenue per share$0.00$0.00$0.05———————
Earnings per share−$0.34−$0.50−$1.29———————
Operating cash flow per share−$0.27−$0.49−$1.23———————
Free cash flow per share−$0.27−$0.49−$1.23———————
Cash per share$0.48$0.34$0.66———————
Book value per share$0.40$0.31$0.99———————
Tangible book value per share$0.19−$0.03$0.37———————
Capex per share$0.00$0.00$0.01———————
Debt per share$0.15$0.25————————
Shares outstanding42.4M25.8M14.3M———————
Change in shares outstanding+64.1%+81.2%————————
Returns & profitability
Return on equity (ROE)−114.2%−117.7%−102.4%———————
Return on invested capital (ROIC)−241.6%−232.0%−128.3%———−464.3%−569.4%−418.8%−386.3%
Return on assets (ROA)−59.6%−67.3%−54.2%67.8%−48.7%−51.2%−50.3%−48.1%−58.7%−37.9%
Return on tangible assets−68.4%−138.1%−158.9%109.9%−45.1%−60.9%−58.3%−39.1%−68.2%−43.2%
Free cash flow margin—————−745.2%——−402.4%−190.8%
Income quality (OCF / net income)———−0.67——————
Financial health
Total debt$6.5M$6.5M—$10.0M$18.6M$25.6M$121.8M$105.7M$102.7M$94.5M
Cash & short-term investments$20.4M$8.9M$9.4M$15.8M$46.6M$42.9M$66.1M$105.7M$60.5M$80.3M
Net debt−$13.9M−$2.3M−$9.4M−$5.7M−$28.0M−$17.3M$55.7M−$45,000$42.2M$14.2M
Debt / equity0.380.82—0.46———24.85——
Debt / assets0.220.36—0.210.240.391.330.881.360.95
Net debt / EBITDA———−0.09——————
Current ratio5.493.562.561.782.732.665.276.784.648.74
Quick ratio5.493.562.561.702.672.565.026.734.578.53
Interest coverage—-38.7-126.0-18.2-7.9-12.4-21.4-2.8-2.8-2.6
Working capital$17.1M$6.8M$7.0M$10.8M$32.0M$29.2M$58.1M$92.1M$49.8M$78.9M
Invested capital$3.2M$5.7M$4.7M$16.1M−$63.9M−$73.0M$14.2M$4.2M$5.7M$8.9M
Tangible asset value$8.2M−$818,001$5.3M$13.0M−$35.9M−$55.8M−$41.4M$4.3M−$36.5M−$5.3M
Net current asset value$8.2M−$818,001$5.3M−$1.1M−$63.3M−$75.2M−$61.1M−$8.3M−$48.6M−$16.3M
Graham net-net per share$0.18−$0.05$0.22———————
Capital allocation
Share buybacks (net)——$22,000$315,000$249,000$86,000————
Capex / revenue0.0%—15.4%20.6%483.3%34.3%151.6%38.1%30.1%21.4%
Capex / depreciation—0.000.320.220.931.002.081.421.381.81
Stock-based compensation / revenue2,496.4%—265.6%163.1%1,219.3%81.7%220.9%240.3%53.7%25.8%
R&D / revenue21,546.4%—851.9%95.7%644.2%74.2%203.6%610.7%242.8%123.3%
SG&A / revenue26,710.7%—1,842.4%960.5%8,183.9%670.8%1,967.1%965.4%—89.9%
Efficiency
Days sales outstanding———48.3383.836.066.4164.1168.195.9
Days of inventory on hand———253.6166.2148.9111.383.153.238.8
Days payables outstanding—54.585.3374.2294.9134.8101.6160.451.146.2
Cash conversion cycle (days)———-72.2255.150.076.086.8170.388.5
Receivables turnover———7.550.9510.155.502.222.173.81
Payables turnover0.006.704.280.981.242.713.592.287.157.90
Inventory turnover———1.442.202.453.284.396.859.40
Asset turnover0.000.000.020.030.010.070.020.020.090.15
Average receivables———$234,500$397,500$533,500$416,500$967,000$3.7M$4.6M
Average payables$607,000$1.0M$1.3M$1.7M$2.4M$2.2M$1.9M$1.7M$1.5M$1.6M
Average inventory———$1.1M$1.4M$2.5M$2.1M$905,000$1.6M$1.3M
Intangibles / total assets29.7%48.4%43.2%18.6%0.0%0.0%0.0%0.0%0.0%0.0%

Computed from TLPH's annual financial statements (latest annual report filed March 23, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

TLPH valuation and financial ratios

Talphera earned a return on equity of −114.2% and a return on invested capital of −241.6% in fiscal 2025. It ended the year with $6.5 million of debt and $20.4 million in cash and short-term investments, a net cash position of $13.9 million.

See the TLPH income statement, the TLPH chart for price history, or the TLPH stock overview for the latest quote and news.

TLPH key metrics FAQ

What is Talphera's return on equity?

Talphera's return on equity (ROE) was −114.2% in fiscal 2025: net income of -$14.3 million on average shareholders' equity of $12.5 million.

What is Talphera's ROIC?

Talphera's return on invested capital was −241.6% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does Talphera have?

Talphera had total debt of $6.5 million at the end of fiscal 2025, a debt-to-equity ratio of 0.38 and more cash than debt.

What is Talphera's free cash flow yield?

Talphera generated -$11.4 million of free cash flow in fiscal 2025, a free cash flow yield of −23.5% on its market value at year-end ($48.3 million).

What is Talphera's current ratio?

Talphera's current ratio was 5.49 at the end of fiscal 2025: current assets were 5.49 times current liabilities.

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