Ultragenyx Pharmaceutical Inc. (RARE) Key Metrics

NASDAQ: RAREValuation, returns, debt and efficiency ratios over 10 years.

RARE valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$1.43B
Enterprise value
$824.0M
P/E (TTM)
—
Forward P/E
—
PEG ratio
—
Price / sales
2.0
10-yr median 16.2
Price / book
19.7
10-yr median 6.2
EV / EBITDA
—
Dividend yield
—
Beta
0.35

RARE key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

RARE valuation Price multiples at each fiscal year-end price.

Price / sales−50.4%
3.4
2025 · hover or tap a bar for each year
2017: 753.82018: 42.0 (−94.4%)2019: 23.3 (−44.6%)2020: 31.1 (+33.4%)2021: 16.2 (−47.8%)2022: 8.9 (−45.0%)2023: 8.1 (−9.2%)2024: 6.8 (−16.1%)2025: 3.4 (−50.4%)
20162025
Free cash flow yield−9.7 pts
−20.8%
2025 · hover or tap a bar for each year
2016: −6.1% (−3.5 pts)2017: −13.0% (−6.9 pts)2018: −13.6% (−0.6 pts)2019: −15.3% (−1.7 pts)2020: −2.1% (+13.2 pts)2021: −7.2% (−5.1 pts)2022: −16.3% (−9.0 pts)2023: −14.8% (+1.4 pts)2024: −11.1% (+3.8 pts)2025: −20.8% (−9.7 pts)
20162025

RARE valuation history

Fiscal year-endToday10-year median

RARE returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

RARE debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

RARE price vs earnings per share

Share price at year-endEPS (right axis)

RARE key metrics

2016–2025
Ultragenyx Pharmaceutical Inc. key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$2.27B$3.81B$3.52B$3.24B$5.70B$8.42B$2.42B$2.16B$1.97B$2.78B
Enterprise value$2.85B$3.24B$2.98B$2.52B$5.00B$7.27B$1.70B$1.70B$1.72B$2.29B
Price / sales3.46.88.18.916.231.123.342.0753.8—
Price / book—14.912.89.26.27.33.73.65.15.9
EV / sales4.25.86.96.914.226.816.433.1660.2—
Earnings yield−25.4%−14.9%−17.2%−21.8%−8.0%−2.2%−16.7%−9.1%−15.3%−8.8%
Free cash flow yield−20.8%−11.1%−14.8%−16.3%−7.2%−2.1%−15.3%−13.6%−13.0%−6.1%
Dividend yield————————0.0%0.0%
Shareholder yield (dividends + buybacks)———0.0%0.0%0.0%0.0%0.0%0.0%0.0%
Share price at fiscal year-end$23.00$42.07$47.82$46.33$84.09$138.43$42.71$43.48$46.38$70.31
Per share
Revenue per share$6.83$6.19$5.90$5.20$5.18$4.45$1.83$1.03$0.06$0.00
Earnings per share−$5.83−$6.29−$8.25−$10.12−$6.70−$3.07−$7.12−$3.97−$7.12−$6.21
Operating cash flow per share−$4.73−$4.57−$6.46−$5.44−$5.00−$2.17−$6.10−$5.84−$5.98−$4.07
Free cash flow per share−$4.79−$4.66−$7.09−$7.53−$6.07−$2.89−$6.54−$5.92−$6.05−$4.32
Cash per share$7.03$6.74$7.85$10.70$10.92$19.75$13.35$9.24$5.76$12.58
Book value per share−$0.81$2.82$3.74$5.04$13.61$18.97$11.56$12.23$9.03$11.97
Tangible book value per share−$3.04$0.36$0.88$2.12$11.02$16.09$8.49$8.74$4.65$11.97
Dividends per share————————$0.00$0.00
Capex per share$0.06$0.08$0.64$2.09$1.08$0.72$0.44$0.08$0.07$0.26
Debt per share$12.94$0.45$0.59$0.45$0.62$0.79$0.65—$0.00$0.00
Shares outstanding98.6M90.5M73.5M69.9M67.8M60.8M56.6M49.8M42.5M39.6M
Change in shares outstanding+8.9%+23.1%+5.2%+3.1%+11.4%+7.5%+13.7%+17.2%+7.2%+7.6%
Returns & profitability
Return on equity (ROE)—−214.5%−193.2%−111.0%−43.7%−20.6%−63.8%−39.8%−70.5%−48.9%
Return on invested capital (ROIC)−448.2%———−267.6%——−203.6%−452.5%—
Return on assets (ROA)−37.9%−38.0%−40.0%−46.1%−27.7%−12.9%−43.4%−32.7%−58.6%−44.7%
Return on tangible assets−43.8%−44.4%−47.4%−52.8%−33.7%−11.8%−41.9%−36.2%−99.1%−45.5%
Free cash flow margin−70.1%−75.3%−120.1%−144.9%−117.2%−65.0%−357.0%−572.2%——
Financial health
Total debt$1.28B$40.3M$43.2M$31.6M$42.0M$48.2M$37.0M—$0$0
Cash & short-term investments$693.0M$610.0M$577.2M$747.8M$740.2M$1.20B$755.2M$459.7M$244.5M$498.1M
Net debt$583.0M−$569.7M−$534.0M−$716.2M−$698.2M−$1.15B−$718.2M−$459.7M−$244.5M−$498.1M
Debt / equity—0.160.160.090.050.040.06—0.000.00
Debt / assets0.830.030.030.020.030.030.03—0.000.00
Current ratio2.482.372.613.384.726.838.246.993.448.27
Quick ratio2.342.242.493.284.636.768.136.903.438.27
Interest coverage-8.6-8.5-8.6-15.1-13.0-9.9-373.7———
Working capital$567.0M$473.0M$451.7M$622.7M$675.2M$1.11B$747.7M$447.6M$173.5M$437.9M
Invested capital$503.0M−$314.4M−$258.6M−$363.7M$224.3M$1.1M−$64.5M$149.2M$139.0M−$24.1M
Tangible asset value−$293.0M$39.6M$64.7M$148.0M$747.4M$978.9M$480.4M$435.3M$197.5M$474.0M
Net current asset value−$654.0M−$424.0M−$483.4M−$309.1M$256.8M$690.1M$369.3M$411.7M$137.2M$431.5M
Graham net-net per share−$7.78−$5.71−$7.70−$5.74$2.68$10.19$5.37$7.28$3.33$10.90
Capital allocation
Dividends paid————————$0$0
Share buybacks (net)———$0$0$0$0$0$0$0
Capex / revenue0.9%1.3%10.8%40.2%20.8%16.2%23.9%7.9%106.9%7,660.2%
Capex / depreciation0.170.211.808.025.523.582.910.210.482.98
Stock-based compensation / revenue22.7%28.2%31.1%35.9%29.9%31.6%79.1%155.6%2,603.9%36,322.6%
R&D / revenue111.4%124.6%149.3%194.3%141.5%152.0%344.6%570.9%8,868.5%137,747.4%
SG&A / revenue51.9%57.4%71.3%76.6%62.6%67.5%155.7%248.0%3,825.0%48,824.1%
Efficiency
Days sales outstanding76.163.647.842.635.137.780.263.5722.7—
Days of inventory on hand162.4187.8245.2277.1333.8732.3377.11,245.7138,152.5—
Days payables outstanding116.8192.4344.7389.3342.7768.1509.53,369.92,600,625.08.3
Cash conversion cycle (days)121.859.1-51.7-69.626.21.9-52.2-2,060.7-2,461,749.8—
Receivables turnover4.795.747.638.5610.419.694.555.750.51—
Payables turnover3.131.901.060.941.070.480.720.110.0044.11
Inventory turnover2.251.941.491.321.090.500.970.290.00—
Asset turnover0.440.370.290.240.210.190.110.090.010.00
Average receivables$140.4M$97.6M$56.9M$42.4M$33.8M$28.0M$22.8M$9.0M$5.2M—
Average payables$34.9M$40.4M$42.7M$30.2M$15.0M$12.9M$12.6M$10.6M$7.1M$4.2M
Average inventory$48.5M$39.5M$30.4M$21.5M$14.6M$12.3M$9.3M$3.9M$378,500$0
Intangibles / total assets14.4%14.8%14.1%13.2%11.5%10.0%15.3%24.1%37.9%0.0%

Computed from RARE's annual financial statements (latest annual report filed February 18, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

RARE valuation and financial ratios

Ultragenyx Pharmaceutical earned a return on invested capital of −448.2% in fiscal 2025. It ended the year with $1.3 billion of debt and $693.0 million in cash and short-term investments, net debt of $583.0 million. The share count rose 149.1% from 39.6M to 98.6M over 9 years.

See the RARE income statement, the RARE chart for price history, or the RARE stock overview for the latest quote and news.

RARE key metrics FAQ

What is Ultragenyx Pharmaceutical's ROIC?

Ultragenyx Pharmaceutical's return on invested capital was −448.2% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does Ultragenyx Pharmaceutical have?

Ultragenyx Pharmaceutical had total debt of $1.3 billion at the end of fiscal 2025.

What is Ultragenyx Pharmaceutical's free cash flow yield?

Ultragenyx Pharmaceutical generated -$472.0 million of free cash flow in fiscal 2025, a free cash flow yield of −20.8% on its market value at year-end ($2.3 billion).

What is Ultragenyx Pharmaceutical's current ratio?

Ultragenyx Pharmaceutical's current ratio was 2.48 at the end of fiscal 2025: current assets were 2.48 times current liabilities.

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