Pacific Biosciences of California, Inc. (PACB) Key Metrics

NASDAQ: PACBValuation, returns, debt and efficiency ratios over 10 years.

PACB valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$537.7M
Enterprise value
$904.4M
P/E (TTM)
—
Forward P/E
—
PEG ratio
—
Price / sales
3.4
10-yr median 10.5
Price / book
170.7
10-yr median 4.6
EV / EBITDA
140.8
Dividend yield
—
Beta
2.19

PACB key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

PACB valuation Price multiples at each fiscal year-end price.

Price / sales+2.3%
3.5
2025 · hover or tap a bar for each year
2016: 3.7 (−65.1%)2017: 3.0 (−20.1%)2018: 12.7 (+326.0%)2019: 8.6 (−32.2%)2020: 57.5 (+567.0%)2021: 32.0 (−44.4%)2022: 14.3 (−55.3%)2023: 12.4 (−13.3%)2024: 3.4 (−72.4%)2025: 3.5 (+2.3%)
20162025
Price / book+9,966.9%
104.9
2025 · hover or tap a bar for each year
2016: 4.0 (−70.4%)2017: 3.2 (−19.0%)2018: 8.8 (+170.5%)2019: 14.3 (+62.9%)2020: 13.5 (−5.2%)2021: 5.3 (−61.0%)2022: 3.3 (−38.2%)2023: 3.5 (+8.7%)2024: 1.0 (−70.6%)2025: 104.9 (+9,966.9%)
20162025
Free cash flow yield+19.9 pts
−20.3%
2025 · hover or tap a bar for each year
2016: −22.5% (−17.3 pts)2017: −27.9% (−5.5 pts)2018: −6.8% (+21.1 pts)2019: −10.4% (−3.5 pts)2020: 0.4% (+10.8 pts)2021: −2.8% (−3.2 pts)2022: −15.3% (−12.4 pts)2023: −11.1% (+4.2 pts)2024: −40.2% (−29.2 pts)2025: −20.3% (+19.9 pts)
20162025

PACB valuation history

Fiscal year-endToday10-year median

PACB returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

PACB debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

PACB price vs earnings per share

Share price at year-endEPS (right axis)

PACB key metrics

2016–2025
Pacific Biosciences of California, Inc. key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$560.9M$527.7M$2.49B$1.84B$4.18B$4.54B$784.0M$999.7M$279.0M$338.8M
Enterprise value$1.04B$810.2M$2.79B$2.01B$4.09B$4.26B$796.6M$918.3M$236.1M$299.5M
P/E ratio—————154.4————
Price / sales3.53.412.414.332.057.58.612.73.03.7
Price / book104.91.03.53.35.313.514.38.83.24.0
Price / free cash flow—————245.8————
Price / operating cash flow—————232.7————
EV / sales6.55.313.915.731.354.08.811.72.53.3
EV / EBITDA—————109.4————
EV / free cash flow—————230.8————
Earnings yield−97.4%−58.7%−12.3%−17.1%−4.3%0.6%−10.7%−10.3%−33.0%−22.0%
Free cash flow yield−20.3%−40.2%−11.1%−15.3%−2.8%0.4%−10.4%−6.8%−27.9%−22.5%
Dividend yield————————0.0%0.0%
Shareholder yield (dividends + buybacks)————0.0%0.0%0.0%0.0%0.0%0.0%
Share price at fiscal year-end$1.87$1.83$9.81$8.18$20.46$25.94$5.14$7.40$2.64$3.80
Per share
Revenue per share$0.53$0.53$0.79$0.57$0.64$0.45$0.60$0.58$0.88$1.02
Earnings per share−$1.82−$1.07−$1.21−$1.40−$0.89$0.17−$0.55−$0.76−$0.87−$0.83
Operating cash flow per share−$0.37−$0.71−$1.05−$1.17−$0.54$0.11−$0.51−$0.49−$0.64−$0.76
Free cash flow per share−$0.38−$0.74−$1.09−$1.25−$0.57$0.11−$0.53−$0.51−$0.74−$0.85
Cash per share$0.93$1.35$2.49$3.44$5.12$1.82$0.32$0.76$0.59$0.81
Book value per share$0.02$1.76$2.77$2.51$3.87$1.92$0.36$0.84$0.81$0.95
Tangible book value per share−$1.09−$0.70−$0.86−$1.15−$0.15$1.92$0.36$0.84$0.81$0.95
Dividends per share————————$0.00$0.00
Capex per share$0.01$0.02$0.03$0.08$0.03$0.01$0.02$0.01$0.10$0.09
Debt per share$2.53$2.33$3.68$4.22$4.68$0.24$0.40$0.16$0.19$0.37
Shares outstanding300.0M288.4M253.6M224.6M204.1M175.0M152.5M135.1M105.7M89.1M
Change in shares outstanding+4.0%+13.7%+12.9%+10.0%+16.7%+14.7%+12.9%+27.8%+18.5%+17.9%
Returns & profitability
Return on equity (ROE)−213.5%−51.3%−48.5%−46.4%−32.2%15.1%−99.6%−102.5%−108.0%−94.0%
Return on invested capital (ROIC)−69.1%−41.8%−30.3%−33.7%−43.7%−165.5%−158.6%−210.5%−160.2%−209.6%
Return on assets (ROA)−53.4%−20.6%−17.5%−16.7%−15.0%10.5%−52.9%−65.3%−65.4%−55.3%
Return on tangible assets−121.1%−56.0%−37.1%−33.2%−15.3%7.1%−56.9%−60.2%−64.0%−53.9%
Free cash flow margin−71.2%−137.8%−137.3%−218.3%−89.7%23.4%−89.3%−86.8%−83.4%−83.9%
Income quality (OCF / net income)—————0.66————
Financial health
Total debt$759.9M$672.4M$933.9M$948.5M$955.4M$42.0M$61.7M$20.9M$19.9M$32.7M
Cash & short-term investments$279.5M$389.9M$631.4M$772.3M$1.04B$318.8M$49.1M$102.4M$62.9M$72.0M
Net debt$480.4M$282.5M$302.5M$176.2M−$89.0M−$276.8M$12.6M−$81.4M−$42.9M−$39.3M
Debt / equity142.071.331.331.681.210.131.120.180.230.39
Debt / assets0.970.530.530.540.480.100.420.120.140.24
Net debt / EBITDA—————−7.10————
Current ratio6.897.487.813.2415.369.241.656.474.553.23
Quick ratio5.996.597.213.0415.018.871.385.593.522.76
Interest coverage-80.2-35.4-23.3-20.9-16.8-391.0-38.5-41.7-30.7-22.0
Working capital$320.6M$429.4M$647.0M$588.7M$1.03B$317.1M$31.9M$111.3M$79.3M$75.2M
Invested capital$485.8M$789.1M$1.00B$739.1M$701.9M$58.7M$67.5M$32.7M$43.2M$45.4M
Tangible asset value−$327.5M−$200.7M−$217.9M−$257.3M−$30.0M$335.5M$54.9M$114.1M$86.1M$84.7M
Net current asset value−$403.7M−$258.2M−$302.7M−$352.1M−$114.8M$277.1M−$12.0M$75.4M$43.6M$55.8M
Graham number—————$2.69————
Graham net-net per share−$1.49−$1.09−$1.41−$1.75−$0.69$1.49−$0.17$0.46$0.25$0.39
Capital allocation
Dividends paid————————$0$0
Share buybacks (net)————$0$0$0$0$0$0
Dividends + buybacks / free cash flow—————0.0%————
Capex / revenue1.7%4.0%4.4%13.2%4.5%1.3%3.1%2.4%11.2%9.0%
Capex / operating cash flow—————5.3%————
Capex / depreciation0.010.120.270.980.510.110.290.261.242.12
Stock-based compensation / revenue26.0%46.1%36.0%61.3%61.9%22.2%18.0%29.4%21.8%21.6%
R&D / revenue60.8%87.6%93.3%150.4%86.5%81.3%65.6%79.6%69.9%74.5%
SG&A / revenue88.4%113.6%84.2%125.4%95.1%92.3%83.1%80.7%63.3%52.7%
Efficiency
Days sales outstanding71.876.050.461.257.474.347.951.148.533.5
Days of inventory on hand180.3180.5132.2172.698.9108.5101.1139.6120.1104.2
Days payables outstanding62.449.533.553.037.147.148.954.054.251.4
Cash conversion cycle (days)189.8207.0149.2180.8119.2135.7100.0136.8114.586.4
Receivables turnover5.084.807.245.966.354.917.627.147.5210.89
Payables turnover5.857.3810.916.889.837.767.466.766.747.10
Inventory turnover2.022.022.762.113.693.363.612.613.043.50
Asset turnover0.160.100.110.070.110.280.570.500.660.67
Average receivables$31.5M$32.1M$27.7M$21.5M$20.5M$16.1M$11.9M$11.0M$12.4M$8.3M
Average payables$18.7M$15.8M$13.5M$11.5M$7.3M$6.0M$7.6M$7.9M$8.7M$6.6M
Average inventory$54.0M$57.7M$53.5M$37.5M$19.4M$13.8M$15.6M$20.5M$19.3M$13.3M
Intangibles / total assets42.5%56.1%52.6%46.4%40.9%0.0%0.0%0.0%0.0%0.0%

Computed from PACB's annual financial statements (latest annual report filed February 25, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

PACB valuation and financial ratios

PacBio earned a return on equity of −213.5% and a return on invested capital of −69.1% in fiscal 2025. It ended the year with $759.9 million of debt and $279.5 million in cash and short-term investments, net debt of $480.4 million. The share count rose 236.5% from 89.1M to 300.0M over 9 years.

See the PACB income statement, the PACB chart for price history, or the PACB stock overview for the latest quote and news.

PACB key metrics FAQ

What is PacBio's return on equity?

PacBio's return on equity (ROE) was −213.5% in fiscal 2025: net income of -$546.4 million on average shareholders' equity of $256.0 million.

What is PacBio's ROIC?

PacBio's return on invested capital was −69.1% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does PacBio have?

PacBio had total debt of $759.9 million at the end of fiscal 2025, a debt-to-equity ratio of 142.07.

What is PacBio's free cash flow yield?

PacBio generated -$113.9 million of free cash flow in fiscal 2025, a free cash flow yield of −20.3% on its market value at year-end ($560.9 million).

What is PacBio's current ratio?

PacBio's current ratio was 6.89 at the end of fiscal 2025: current assets were 6.89 times current liabilities.

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