Maze Therapeutics, Inc. (MAZE) Key Metrics

NASDAQ: MAZEValuation, returns, debt and efficiency ratios over 4 years.

MAZE valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$1.53B
Enterprise value
$1.21B
P/E (TTM)
—
Forward P/E
8.5
PEG ratio
—
Price / sales
76.5
Price / book
3.4
EV / EBITDA
6.1
Dividend yield
—
Beta
—

MAZE key metrics, 2022–2025

Fiscal year ended December 31, 2025 · U.S. dollars

MAZE returns How much profit the business earns on the capital it uses.

Return on equity−98.0 pts
−47.5%
2025 · hover or tap a bar for each year
2022: −113.3%2023: −180.1% (−66.8 pts)2024: 50.5% (+230.6 pts)2025: −47.5% (−98.0 pts)
20222025
Return on invested capital−554.8 pts
−358.0%
2025 · hover or tap a bar for each year
2022: −261.2%2023: −242.9% (+18.3 pts)2024: 196.8% (+439.7 pts)2025: −358.0% (−554.8 pts)
20222025
Return on assets−74.6 pts
−41.1%
2025 · hover or tap a bar for each year
2022: −76.6%2023: −90.7% (−14.0 pts)2024: 33.5% (+124.2 pts)2025: −41.1% (−74.6 pts)
20222025
Asset turnover−100.0%
0.00
2025 · hover or tap a bar for each year
2022: 0.002023: 0.002024: 1.072025: 0.00 (−100.0%)
20222025

MAZE valuation history

Fiscal year-endToday4-year median

MAZE returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

MAZE debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

MAZE price vs earnings per share

Share price at year-endEPS (right axis)

MAZE key metrics

2022–2025
Maze Therapeutics, Inc. key metrics by fiscal year
2025202420232022
Valuation
Market capitalization$1.78B———
Enterprise value$1.46B———
Price / book5.0———
Earnings yield−7.4%———
Free cash flow yield−6.3%———
Shareholder yield (dividends + buybacks)0.0%———
Share price at fiscal year-end$41.43———
Per share
Revenue per share$0.00$3.82$0.00$0.00
Earnings per share−$3.05$1.19−$2.29−$2.63
Operating cash flow per share−$2.60$1.73−$1.98−$2.27
Free cash flow per share−$2.62$1.71−$1.99−$2.31
Cash per share$7.96$4.49$0.67$2.28
Book value per share$8.26$4.50$0.23$2.32
Tangible book value per share$8.26$4.50$0.23$2.32
Capex per share$0.02$0.03$0.01$0.04
Debt per share$0.54$0.61$1.13$0.73
Shares outstanding43.0M43.8M43.8M43.8M
Change in shares outstanding−1.9%+0.0%0.0%—
Returns & profitability
Return on equity (ROE)−47.5%50.5%−180.1%−113.3%
Return on invested capital (ROIC)−358.0%196.8%−242.9%−261.2%
Return on assets (ROA)−41.1%33.5%−90.7%−76.6%
Return on tangible assets−33.0%21.7%−140.4%−76.6%
Free cash flow margin—44.7%——
Income quality (OCF / net income)—1.45——
Financial health
Total debt$23.3M$26.6M$49.6M$32.1M
Cash & short-term investments$341.9M$196.8M$29.2M$99.9M
Net debt−$318.6M−$170.2M$20.5M−$67.9M
Debt / equity0.070.144.940.32
Debt / assets0.060.110.690.21
Net debt / EBITDA—−3.00——
Current ratio15.509.762.095.11
Quick ratio15.509.762.095.11
Working capital$327.2M$181.0M$17.8M$85.4M
Invested capital$36.4M$26.7M$30.5M$33.6M
Tangible asset value$355.0M$196.9M$10.1M$101.4M
Net current asset value$307.6M$158.0M−$27.3M$57.6M
Graham number—$10.98——
Graham net-net per share$7.00$3.50−$0.74$1.17
Capital allocation
Share buybacks (net)$0———
Capex / revenue—0.7%——
Capex / operating cash flow—1.5%——
Capex / depreciation0.330.350.110.51
Stock-based compensation / revenue—5.8%——
R&D / revenue—49.8%——
SG&A / revenue—15.8%——
Efficiency
Days payables outstanding283.5219.1160.9151.4
Receivables turnover0.00———
Payables turnover1.291.672.272.41
Asset turnover0.001.070.000.00
Average receivables$1.5M———
Average payables$1.9M$2.0M$1.8M$1.6M
Intangibles / total assets0.0%0.0%0.0%0.0%

Computed from MAZE's annual financial statements (latest annual report filed March 25, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

MAZE valuation and financial ratios

Maze Therapeutics earned a return on equity of −47.5% and a return on invested capital of −358.0% in fiscal 2025. It ended the year with $23.3 million of debt and $341.9 million in cash and short-term investments, a net cash position of $318.6 million.

See the MAZE income statement, the MAZE chart for price history, or the MAZE stock overview for the latest quote and news.

MAZE key metrics FAQ

What is Maze Therapeutics's return on equity?

Maze Therapeutics's return on equity (ROE) was −47.5% in fiscal 2025: net income of -$131.1 million on average shareholders' equity of $275.9 million.

What is Maze Therapeutics's ROIC?

Maze Therapeutics's return on invested capital was −358.0% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does Maze Therapeutics have?

Maze Therapeutics had total debt of $23.3 million at the end of fiscal 2025, a debt-to-equity ratio of 0.07 and more cash than debt.

What is Maze Therapeutics's free cash flow yield?

Maze Therapeutics generated -$112.7 million of free cash flow in fiscal 2025, a free cash flow yield of −6.3% on its market value at year-end ($1.8 billion).

What is Maze Therapeutics's current ratio?

Maze Therapeutics's current ratio was 15.50 at the end of fiscal 2025: current assets were 15.50 times current liabilities.

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