Ligand Pharmaceuticals Incorporated (LGND) Key Metrics

NASDAQ: LGNDValuation, returns, debt and efficiency ratios over 10 years.

LGND valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$5.89B
Enterprise value
$5.72B
P/E (TTM)
31.1
10-yr median 26.7
Forward P/E
24.8
PEG ratio
1.53
Price / sales
20.3
10-yr median 10.2
Price / book
6.2
10-yr median 2.2
EV / EBITDA
20.6
10-yr median 15.4
Dividend yield
—
Beta
1.01

LGND key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

LGND valuation Price multiples at each fiscal year-end price.

P/E ratio
30.8
2025 · hover or tap a bar for each year
2017: 159.72018: 14.2 (−91.1%)2019: 2.0 (−85.6%)2021: 29.12023: 24.32025: 30.8
20162025
Price / sales+22.1%
14.3
2025 · hover or tap a bar for each year
2016: 12.1 (−39.3%)2017: 14.2 (+17.3%)2018: 8.1 (−43.0%)2019: 10.7 (+31.9%)2020: 6.1 (−42.6%)2021: 6.9 (+12.1%)2022: 5.7 (−16.5%)2023: 9.7 (+68.2%)2024: 11.7 (+21.4%)2025: 14.3 (+22.1%)
20162025
Price / book+59.8%
3.8
2025 · hover or tap a bar for each year
2016: 3.6 (−24.5%)2017: 4.8 (+34.6%)2018: 3.6 (−24.2%)2019: 1.7 (−53.9%)2020: 1.4 (−15.5%)2021: 2.0 (+43.0%)2022: 1.9 (−6.8%)2023: 1.8 (−4.1%)2024: 2.4 (+30.4%)2025: 3.8 (+59.8%)
20162025
EV / EBITDA−56.0%
18.4
2025 · hover or tap a bar for each year
2016: 25.8 (−46.4%)2017: 25.5 (−1.1%)2018: 8.1 (−68.3%)2019: 1.0 (−87.8%)2020: 18.5 (+1,773.9%)2021: 11.5 (−37.8%)2022: 12.3 (+7.2%)2023: 10.9 (−11.3%)2024: 41.9 (+283.0%)2025: 18.4 (−56.0%)
20162025
Price / free cash flow+209.9%
78.5
2025 · hover or tap a bar for each year
2016: 38.1 (−18.1%)2017: 23.2 (−39.0%)2018: 11.2 (−51.8%)2020: 20.02021: 23.7 (+18.5%)2022: 9.4 (−60.4%)2024: 25.32025: 78.5 (+209.9%)
20162025
Free cash flow yield−2.7 pts
1.3%
2025 · hover or tap a bar for each year
2016: 2.6% (+0.5 pts)2017: 4.3% (+1.7 pts)2018: 8.9% (+4.6 pts)2019: −2.5% (−11.4 pts)2020: 5.0% (+7.5 pts)2021: 4.2% (−0.8 pts)2022: 10.6% (+6.4 pts)2023: −0.3% (−11.0 pts)2024: 3.9% (+4.3 pts)2025: 1.3% (−2.7 pts)
20162025

LGND valuation history

Fiscal year-endToday10-year median

LGND returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

LGND debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

LGND cash returned to shareholders

DividendsBuybacksFree cash flow

LGND price vs earnings per share

Share price at year-endEPS (right axis)

LGND key metrics

2016–2025
Ligand Pharmaceuticals Incorporated key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$3.84B$1.96B$1.27B$1.13B$1.66B$1.00B$1.29B$2.04B$2.01B$1.32B
Enterprise value$3.55B$1.71B$1.10B$1.00B$1.65B$1.05B$865.7M$1.91B$2.05B$1.42B
P/E ratio30.8—24.3—29.1—2.014.2159.7—
Price / sales14.311.79.75.76.96.110.78.114.212.1
Price / book3.82.41.81.92.01.41.73.64.83.6
Price / free cash flow78.525.3—9.423.720.0—11.223.238.1
Price / operating cash flow77.720.225.68.221.118.4—10.521.421.0
EV / sales13.310.28.45.16.86.47.27.614.513.0
EV / EBITDA18.441.910.912.311.518.51.08.125.525.8
EV / free cash flow72.722.1—8.423.520.9—10.523.741.0
Earnings yield3.2%−0.2%4.1%−3.0%3.4%−0.3%49.0%7.0%0.6%−0.1%
Free cash flow yield1.3%3.9%−0.3%10.6%4.2%5.0%−2.5%8.9%4.3%2.6%
Dividend yield———0.4%0.9%0.3%0.2%—0.0%0.0%
Shareholder yield (dividends + buybacks)0.4%0.3%0.4%1.2%2.0%8.1%35.5%6.0%0.1%0.3%
Share price at fiscal year-end$189.07$107.15$71.42$66.80$96.36$62.04$65.06$84.65$85.42$63.39
Per share
Revenue per share$13.21$9.14$7.40$11.63$14.01$10.11$6.09$10.45$6.01$5.23
Earnings per share$6.13−$0.22$2.94−$1.98$3.31−$0.18$31.85$5.96$0.53−$0.08
Operating cash flow per share$2.43$5.31$2.79$8.17$4.57$3.37−$1.48$8.06$3.98$3.02
Free cash flow per share$2.41$4.23−$0.24$7.11$4.06$3.10−$1.61$7.57$3.68$1.66
Cash per share$36.14$14.01$9.59$12.56$19.78$25.41$54.15$31.77$8.59$6.77
Book value per share$50.12$45.40$39.47$35.42$47.61$43.84$38.83$23.31$17.83$17.80
Tangible book value per share$24.31$25.07$16.78$8.25$19.06−$5.34$22.34$9.27$3.60$3.27
Dividends per share———$0.30$0.89$0.19$0.15—$0.00$0.00
Capex per share$0.02$1.07$3.03$1.06$0.51$0.28$0.13$0.49$0.30$1.36
Debt per share$22.25$0.39$0.35$5.20$18.81$28.20$32.91$26.44$10.37$11.64
Shares outstanding20.3M18.3M17.8M16.9M17.2M16.2M19.8M24.1M23.5M20.8M
Change in shares outstanding+11.0%+3.0%+5.3%−2.2%+6.6%−18.1%−17.9%+2.5%+12.7%−1.9%
Returns & profitability
Return on equity (ROE)13.5%−0.5%8.0%−4.7%7.5%−0.4%94.8%29.3%3.2%−0.5%
Return on invested capital (ROIC)5.6%−2.0%2.0%0.2%13.3%6.8%163.4%30.3%7.3%5.6%
Return on assets (ROA)9.9%−0.5%6.7%−3.2%4.3%−0.2%45.7%14.8%2.0%−0.3%
Return on tangible assets12.0%−0.7%13.6%−11.0%7.1%−0.5%53.8%15.5%3.7%−0.5%
Free cash flow margin18.2%46.3%−3.3%61.1%29.0%30.6%−26.5%72.4%61.2%31.8%
Income quality (OCF / net income)0.40—0.95—1.38—−0.051.357.45—
Financial health
Total debt$451.5M$7.1M$6.2M$87.7M$324.4M$456.4M$650.2M$636.3M$243.4M$242.5M
Cash & short-term investments$733.5M$256.2M$170.3M$211.9M$341.1M$411.2M$1.07B$764.6M$201.7M$141.0M
Net debt−$282.0M−$249.1M−$164.1M−$124.1M−$16.7M$45.2M−$419.7M−$128.3M$41.7M$101.4M
Debt / equity0.440.010.010.150.400.640.851.130.580.65
Debt / assets0.290.010.010.120.250.340.430.500.360.40
Net debt / EBITDA−1.46−6.11−1.63−1.53−0.120.80−0.48−0.540.521.84
Current ratio22.238.9314.152.6711.155.0066.0910.580.990.72
Quick ratio21.988.5512.722.5310.504.7465.6610.500.970.71
Interest coverage10.0-7.418.21.75.31.422.63.46.03.6
Working capital$794.8M$294.4M$220.6M$164.8M$423.1M$400.4M$1.11B$788.3M−$1.8M−$64.1M
Invested capital$735.2M$581.4M$536.8M$473.4M$804.4M$754.8M$347.5M$432.6M$460.4M$472.3M
Tangible asset value$493.4M$458.5M$297.9M$139.2M$328.7M−$86.4M$441.5M$223.0M$84.6M$68.1M
Net current asset value$288.8M$220.2M$151.1M$98.4M−$11.7M−$152.2M$396.0M$170.7M−$15.4M−$67.7M
Graham number$83.16—$51.07—$59.58—$166.83$55.88$14.65—
Graham net-net per share$11.85$10.05$7.07$4.72−$3.07−$11.37$19.09$4.58−$1.13−$3.61
Capital allocation
Dividends paid———$5.0M$15.3M$3.0M$3.0M—$0$0
Share buybacks (net)$15.0M$5.1M$4.5M$8.2M$18.4M$78.0M$453.0M$122.9M$2.0M$3.9M
Dividend payout ratio————26.8%—0.5%—0.0%—
Dividends + buybacks / free cash flow30.7%6.6%—11.0%48.2%161.6%—67.4%2.3%11.2%
Capex / revenue0.2%11.8%41.0%9.1%3.6%2.7%2.1%4.7%5.1%26.0%
Capex / operating cash flow0.9%20.2%108.6%13.0%11.1%8.2%—6.1%7.6%45.0%
Capex / depreciation0.010.561.470.410.170.160.060.810.612.51
Stock-based compensation / revenue17.5%24.6%19.6%30.7%16.1%18.8%20.4%8.3%17.7%17.3%
R&D / revenue30.3%12.8%18.7%18.4%13.3%24.8%46.5%11.1%19.1%19.5%
SG&A / revenue34.5%47.1%40.2%35.7%19.4%36.7%34.8%15.0%20.3%24.4%
Efficiency
Days sales outstanding70.589.3103.3117.8113.9112.5148.161.961.349.6
Days of inventory on hand643.8627.6194.0140.3158.0202.7231.9331.1214.1116.5
Days payables outstanding234.7126.240.347.435.837.2106.2398.0638.3432.9
Cash conversion cycle (days)479.6590.7257.1210.8236.1277.9273.8-4.9-362.9-266.8
Receivables turnover5.184.093.533.103.213.242.465.895.967.37
Payables turnover1.562.899.067.7110.209.813.440.920.570.84
Inventory turnover0.570.581.882.602.311.801.571.101.703.13
Asset turnover0.210.190.170.190.180.110.090.260.220.19
Average receivables$51.7M$40.9M$37.2M$63.3M$75.4M$50.4M$48.8M$42.7M$23.7M$14.8M
Average payables$4.2M$3.8M$3.9M$6.9M$6.1M$3.1M$3.3M$6.9M$9.4M$6.6M
Average inventory$11.6M$19.0M$18.6M$20.3M$26.9M$16.9M$7.2M$5.7M$3.1M$1.8M
Intangibles / total assets33.6%39.5%51.2%60.1%38.0%58.4%21.8%26.8%49.8%50.3%

Computed from LGND's annual financial statements (latest annual report filed February 27, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

LGND valuation and financial ratios

At the end of fiscal 2025 (December 31, 2025), Ligand Pharmaceuticals traded at 30.8 times earnings, against a 10-year median of 26.7. Based on the latest twelve months, the trailing P/E is 31.1 and the forward P/E is 24.8. Ligand Pharmaceuticals earned a return on equity of 13.5% and a return on invested capital of 5.6% in fiscal 2025. It ended the year with $451.5 million of debt and $733.5 million in cash and short-term investments, a net cash position of $282.0 million. It returned $15.0 million to shareholders: $0 in dividends and $15.0 million in share buybacks, 31% of free cash flow.

See the LGND income statement, the LGND chart for price history, or the LGND stock overview for the latest quote and news.

LGND key metrics FAQ

What is Ligand Pharmaceuticals's P/E ratio?

Ligand Pharmaceuticals's trailing P/E ratio is 31.1 based on the last twelve months of earnings (as of October 18, 2026), and its forward P/E is 24.8. At the end of fiscal 2025 it was 30.8, compared with a 10-year median of 26.7.

What is Ligand Pharmaceuticals's EV/EBITDA?

Ligand Pharmaceuticals's enterprise value was 18.4 times EBITDA at the end of fiscal 2025 (enterprise value $3.6 billion, EBITDA $192.7 million); the current EV/EBITDA is 20.6.

What is Ligand Pharmaceuticals's return on equity?

Ligand Pharmaceuticals's return on equity (ROE) was 13.5% in fiscal 2025: net income of $124.5 million on average shareholders' equity of $923.8 million.

What is Ligand Pharmaceuticals's ROIC?

Ligand Pharmaceuticals's return on invested capital was 5.6% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does Ligand Pharmaceuticals have?

Ligand Pharmaceuticals had total debt of $451.5 million at the end of fiscal 2025, a debt-to-equity ratio of 0.44 and more cash than debt.

Does Ligand Pharmaceuticals buy back its shares?

Yes. Ligand Pharmaceuticals spent $15.0 million on net share repurchases in fiscal 2025 Shares outstanding changed +11.0% over the year, to 20.3M..

What is Ligand Pharmaceuticals's free cash flow yield?

Ligand Pharmaceuticals generated $48.9 million of free cash flow in fiscal 2025, a free cash flow yield of 1.3% on its market value at year-end ($3.8 billion).

What is Ligand Pharmaceuticals's current ratio?

Ligand Pharmaceuticals's current ratio was 22.23 at the end of fiscal 2025: current assets were 22.23 times current liabilities.

Biotechnology key metrics