Insmed Incorporated (INSM) Key Metrics

NASDAQ: INSMValuation, returns, debt and efficiency ratios over 10 years.

INSM valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$21.02B
Enterprise value
$25.80B
P/E (TTM)
—
Forward P/E
97.1
PEG ratio
1.09
Price / sales
18.5
10-yr median 18.0
Price / book
34.8
10-yr median 7.7
EV / EBITDA
—
Dividend yield
—
Beta
0.82

INSM key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

INSM valuation Price multiples at each fiscal year-end price.

Price / sales+96.9%
61.3
2025 · hover or tap a bar for each year
2018: 102.62019: 14.8 (−85.6%)2020: 19.8 (+33.6%)2021: 16.2 (−18.0%)2022: 10.0 (−38.2%)2023: 14.3 (+42.3%)2024: 31.1 (+118.4%)2025: 61.3 (+96.9%)
20162025
Price / book+26.8%
50.3
2025 · hover or tap a bar for each year
2016: 5.3 (+55.2%)2017: 5.7 (+8.5%)2018: 4.8 (−15.8%)2019: 7.7 (+59.3%)2020: 11.8 (+52.6%)2021: 7.4 (−36.8%)2022: 28.0 (+275.7%)2024: 39.72025: 50.3 (+26.8%)
20162025
Free cash flow yield+3.6 pts
−2.6%
2025 · hover or tap a bar for each year
2016: −18.4% (−8.6 pts)2017: −7.8% (+10.6 pts)2018: −27.0% (−19.2 pts)2019: −14.5% (+12.5 pts)2020: −7.0% (+7.5 pts)2021: −12.1% (−5.2 pts)2022: −16.7% (−4.6 pts)2023: −12.6% (+4.1 pts)2024: −6.2% (+6.4 pts)2025: −2.6% (+3.6 pts)
20162025

INSM valuation history

Fiscal year-endToday10-year median

INSM returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

INSM debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

INSM price vs earnings per share

Share price at year-endEPS (right axis)

INSM key metrics

2016–2025
Insmed Incorporated key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$37.18B$11.33B$4.35B$2.46B$3.05B$3.25B$2.02B$1.01B$2.08B$818.8M
Enterprise value$36.52B$11.21B$4.78B$2.49B$2.95B$3.12B$1.93B$830.3M$1.75B$711.0M
Price / sales61.331.114.310.016.219.814.8102.6——
Price / book50.339.7—28.07.411.87.74.85.75.3
EV / sales60.230.815.610.115.619.014.184.4——
Earnings yield−3.4%−8.1%−17.2%−19.6%−14.2%−9.1%−12.6%−32.1%−9.3%−21.5%
Free cash flow yield−2.6%−6.2%−12.6%−16.7%−12.1%−7.0%−14.5%−27.0%−7.8%−18.4%
Dividend yield————————0.0%0.0%
Shareholder yield (dividends + buybacks)———0.0%0.0%0.0%0.0%0.0%0.0%0.0%
Share price at fiscal year-end$174.04$69.04$30.99$19.98$27.24$33.29$23.88$13.12$31.18$13.23
Per share
Revenue per share$2.84$2.22$2.17$1.99$1.68$1.68$1.61$0.13$0.00$0.00
Earnings per share−$5.98−$5.57−$5.34−$3.91−$3.88−$3.01−$3.01−$4.22−$2.89−$2.85
Operating cash flow per share−$4.38−$4.17−$3.82−$3.25−$3.24−$2.25−$2.96−$3.36−$2.40−$2.37
Free cash flow per share−$4.53−$4.30−$3.91−$3.33−$3.31−$2.32−$3.46−$3.55−$2.44−$2.44
Cash per share$6.69$8.74$5.56$9.33$6.39$5.46$5.76$6.44$5.73$2.63
Book value per share$3.46$1.74−$2.36$0.71$3.66$2.83$3.09$2.71$5.42$2.50
Tangible book value per share$2.36$0.55−$3.79−$0.95$1.79$1.82$1.82$1.18$3.67$0.62
Dividends per share————————$0.00$0.00
Capex per share$0.15$0.13$0.09$0.08$0.07$0.07$0.50$0.19$0.05$0.07
Debt per share$3.60$8.01$8.57$9.57$5.46$4.15$4.70$4.12$0.83$0.89
Shares outstanding213.6M164.0M140.4M123.0M112.1M97.6M84.6M76.9M66.6M61.9M
Change in shares outstanding+30.2%+16.8%+14.1%+9.7%+14.9%+15.4%+10.0%+15.5%+7.6%+5.6%
Returns & profitability
Return on equity (ROE)−249.3%——−193.2%−126.7%−109.4%−108.2%−113.9%−74.7%−75.6%
Return on invested capital (ROIC)−765.9%−539.3%−536.1%−170.6%−130.6%−131.3%−184.9%−744.6%−363.4%−272.2%
Return on assets (ROA)−59.5%−54.5%−50.2%−33.2%−42.6%−38.2%−37.8%−60.8%−55.0%−59.3%
Return on tangible assets−62.9%−49.9%−66.3%−33.2%−42.1%−42.2%−40.1%−66.6%−55.7%−145.0%
Free cash flow margin−159.6%−194.1%−180.1%−167.2%−196.6%−137.6%−214.6%———
Financial health
Total debt$768.2M$1.31B$1.20B$1.18B$612.3M$404.8M$397.0M$316.6M$55.6M$54.8M
Cash & short-term investments$1.43B$1.43B$780.4M$1.15B$716.8M$532.8M$487.4M$495.1M$381.2M$162.6M
Net debt−$661.9M−$119.7M$423.5M$29.6M−$104.5M−$127.9M−$90.4M−$178.5M−$325.6M−$107.8M
Debt / equity1.044.60—13.391.491.471.521.520.150.35
Debt / assets0.340.650.910.710.490.510.530.520.120.23
Current ratio3.835.454.126.696.195.246.516.518.726.02
Quick ratio3.545.123.756.335.704.836.186.428.726.02
Interest coverage-14.0-10.3-8.7-17.3-9.3-9.0-8.5-12.1-31.9-49.6
Working capital$1.33B$1.32B$703.4M$1.08B$701.9M$504.1M$470.0M$439.2M$344.8M$140.4M
Invested capital$77.1M$165.7M$91.6M$117.5M$306.0M$148.0M$171.3M$29.8M$35.5M$46.7M
Tangible asset value$505.2M$90.6M−$531.7M−$116.9M$200.5M$177.4M$154.3M$90.9M$244.7M$38.1M
Net current asset value$268.6M−$118.2M−$732.7M−$295.1M$4.0M$102.6M$74.6M$122.7M$288.5M$84.9M
Graham net-net per share$0.36−$1.33−$5.76−$2.95−$0.58$0.51$0.42$1.38$4.21$1.28
Capital allocation
Dividends paid————————$0$0
Share buybacks (net)———$0$0$0$0$0$0$0
Capex / revenue5.4%6.0%4.4%4.0%3.9%4.1%31.0%150.6%——
Capex / depreciation1.981.991.260.960.510.484.153.071.031.72
Stock-based compensation / revenue25.2%26.6%24.5%23.5%24.4%22.0%19.8%266.8%——
R&D / revenue127.2%164.5%187.1%162.0%144.7%110.2%96.5%1,477.2%——
SG&A / revenue115.6%126.8%112.9%108.3%124.3%123.8%154.5%1,710.4%——
Efficiency
Days sales outstanding58.046.842.440.239.639.733.1204.7——
Days of inventory on hand337.1387.0426.3453.3482.0356.6266.4529.6——
Days payables outstanding223.5294.6322.4285.5325.0256.5233.12,441.31,579.71,340.5
Cash conversion cycle (days)171.6139.1146.3208.0196.5139.866.4-1,706.9——
Receivables turnover6.297.808.619.089.219.1911.031.78——
Payables turnover1.631.241.131.281.121.421.570.150.230.27
Inventory turnover1.080.940.860.810.761.021.370.69——
Asset turnover0.280.220.200.170.180.210.200.020.000.00
Average receivables$96.4M$46.6M$35.5M$27.0M$20.5M$17.9M$12.4M$5.5M——
Average payables$76.5M$69.2M$57.9M$43.1M$39.3M$28.0M$15.5M$16.2M$12.6M$9.0M
Average inventory$115.3M$90.9M$76.6M$68.5M$58.3M$39.0M$17.7M$3.5M$0$0
Intangibles / total assets10.3%9.6%15.0%12.4%16.9%12.4%14.5%19.4%25.2%48.9%

Computed from INSM's annual financial statements (latest annual report filed February 19, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

INSM valuation and financial ratios

Insmed earned a return on equity of −249.3% and a return on invested capital of −765.9% in fiscal 2025. It ended the year with $768.2 million of debt and $1.4 billion in cash and short-term investments, a net cash position of $661.9 million. The share count rose 245.2% from 61.9M to 213.6M over 9 years.

See the INSM income statement, the INSM chart for price history, or the INSM stock overview for the latest quote and news.

INSM key metrics FAQ

What is Insmed's return on equity?

Insmed's return on equity (ROE) was −249.3% in fiscal 2025: net income of -$1.3 billion on average shareholders' equity of $512.2 million.

What is Insmed's ROIC?

Insmed's return on invested capital was −765.9% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does Insmed have?

Insmed had total debt of $768.2 million at the end of fiscal 2025, a debt-to-equity ratio of 1.04 and more cash than debt.

What is Insmed's free cash flow yield?

Insmed generated -$967.6 million of free cash flow in fiscal 2025, a free cash flow yield of −2.6% on its market value at year-end ($37.2 billion).

What is Insmed's current ratio?

Insmed's current ratio was 3.83 at the end of fiscal 2025: current assets were 3.83 times current liabilities.

Biotechnology key metrics