Illumina, Inc. (ILMN) Key Metrics

NASDAQ: ILMNValuation, returns, debt and efficiency ratios over 10 years.

ILMN valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$39.64B
Enterprise value
$38.73B
P/E (TTM)
49.0
10-yr median 48.0
Forward P/E
40.3
PEG ratio
3.05
Price / sales
8.8
10-yr median 9.6
Price / book
13.2
10-yr median 8.5
EV / EBITDA
28.0
10-yr median 39.7
Dividend yield
—
Beta
1.42

ILMN key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

ILMN valuation Price multiples at each fiscal year-end price.

P/E ratio
24.1
2025 · hover or tap a bar for each year
2016: 39.8 (−33.9%)2017: 43.3 (+8.7%)2018: 52.6 (+21.5%)2019: 48.0 (−8.8%)2020: 81.2 (+69.2%)2021: 73.3 (−9.7%)2025: 24.1
20162025
Price / sales−2.9%
4.7
2025 · hover or tap a bar for each year
2016: 7.7 (−38.7%)2017: 11.4 (+48.7%)2018: 13.0 (+14.1%)2019: 13.6 (+4.1%)2020: 16.4 (+21.2%)2021: 12.3 (−24.9%)2022: 6.7 (−45.4%)2023: 4.8 (−29.5%)2024: 4.9 (+2.3%)2025: 4.7 (−2.9%)
20162025
Price / book−16.1%
7.5
2025 · hover or tap a bar for each year
2016: 8.1 (−46.0%)2017: 11.1 (+36.2%)2018: 11.3 (+2.2%)2019: 10.4 (−7.8%)2020: 11.3 (+8.9%)2021: 5.2 (−54.2%)2022: 4.7 (−10.1%)2023: 3.7 (−20.4%)2024: 9.0 (+140.4%)2025: 7.5 (−16.1%)
20162025
EV / EBITDA
14.7
2025 · hover or tap a bar for each year
2016: 24.4 (−33.3%)2017: 40.0 (+64.1%)2018: 39.5 (−1.3%)2019: 39.7 (+0.4%)2020: 89.1 (+124.6%)2021: 446.0 (+400.3%)2025: 14.7
20162025
Price / free cash flow−26.7%
22.0
2025 · hover or tap a bar for each year
2016: 44.3 (−17.7%)2017: 55.9 (+26.0%)2018: 51.4 (−8.0%)2019: 57.1 (+11.1%)2020: 59.8 (+4.7%)2021: 165.8 (+177.4%)2022: 291.3 (+75.7%)2023: 75.9 (−74.0%)2024: 30.0 (−60.5%)2025: 22.0 (−26.7%)
20162025
Free cash flow yield+1.2 pts
4.6%
2025 · hover or tap a bar for each year
2016: 2.3% (+0.4 pts)2017: 1.8% (−0.5 pts)2018: 1.9% (+0.2 pts)2019: 1.8% (−0.2 pts)2020: 1.7% (−0.1 pts)2021: 0.6% (−1.1 pts)2022: 0.3% (−0.3 pts)2023: 1.3% (+1.0 pts)2024: 3.3% (+2.0 pts)2025: 4.6% (+1.2 pts)
20162025

ILMN valuation history

Fiscal year-endToday10-year median

ILMN returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

ILMN debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

ILMN cash returned to shareholders

DividendsBuybacksFree cash flow

ILMN price vs earnings per share

Share price at year-endEPS (right axis)

ILMN key metrics

2016–2025
Illumina, Inc. key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$20.46B$21.25B$21.40B$30.88B$55.88B$53.27B$48.08B$43.47B$31.46B$18.43B
Enterprise value$21.38B$22.65B$22.61B$32.40B$57.08B$51.70B$46.55B$41.96B$30.50B$17.92B
P/E ratio24.1———73.381.248.052.643.339.8
Price / sales4.74.94.86.712.316.413.613.011.47.7
Price / book7.59.03.74.75.211.310.411.311.18.1
Price / free cash flow22.030.075.9291.3165.859.857.151.455.944.3
Price / operating cash flow19.025.444.878.8102.549.345.738.135.926.8
EV / sales4.95.25.07.112.616.013.112.611.17.5
EV / EBITDA14.7———446.089.139.739.540.024.4
EV / free cash flow23.031.980.2305.6169.458.055.349.654.243.1
Earnings yield4.2%−5.8%−5.4%−14.3%1.4%1.2%2.1%1.9%2.3%2.5%
Free cash flow yield4.6%3.3%1.3%0.3%0.6%1.7%1.8%1.9%1.8%2.3%
Dividend yield———3.0%0.9%——1.7%0.0%0.1%
Shareholder yield (dividends + buybacks)3.6%0.5%0.2%3.2%1.8%1.4%0.7%2.2%0.8%1.4%
Share price at fiscal year-end$131.16$133.63$135.45$196.69$370.08$359.92$322.70$291.76$212.54$124.55
Per share
Revenue per share$27.81$27.50$28.51$29.20$29.97$21.89$23.78$22.37$18.59$16.21
Earnings per share$5.45−$7.69−$7.35−$28.05$5.05$4.43$6.72$5.54$4.91$3.13
Operating cash flow per share$6.92$5.26$3.03$2.50$3.61$7.30$7.05$7.66$5.91$4.64
Free cash flow per share$5.97$4.46$1.78$0.68$2.23$6.02$5.65$5.68$3.80$2.81
Cash per share$10.47$7.67$6.67$12.97$8.87$23.46$22.91$23.57$14.49$10.53
Book value per share$17.46$14.92$36.36$42.03$71.13$31.72$30.96$25.81$19.22$15.34
Tangible book value per share$8.97$6.07$1.31$0.48$2.50$24.70$24.46$18.99$12.82$8.46
Dividends per share———$5.97$3.38——$4.93$0.03$0.08
Capex per share$0.95$0.81$1.23$1.82$1.38$1.28$1.40$1.99$2.11$1.83
Debt per share$16.37$16.49$14.32$22.64$16.82$12.88$12.62$13.40$8.05$7.09
Shares outstanding156.0M159.0M158.0M157.0M151.0M148.0M149.0M149.0M148.0M148.0M
Change in shares outstanding−1.9%+0.6%+0.6%+4.0%+2.0%−0.7%0.0%+0.7%0.0%−0.7%
Returns & profitability
Return on equity (ROE)33.4%−30.1%−18.8%−50.8%9.9%14.1%23.7%24.7%28.4%22.5%
Return on invested capital (ROIC)18.2%−12.3%−11.2%−32.9%−1.4%9.7%32.2%36.6%21.6%27.0%
Return on assets (ROA)13.1%−14.9%−10.4%−32.1%6.7%8.8%14.0%13.5%15.2%11.6%
Return on tangible assets16.0%−25.0%−25.4%−76.9%15.7%10.0%15.8%13.9%16.8%14.2%
Free cash flow margin21.5%16.2%6.3%2.3%7.4%27.5%23.8%25.4%20.5%17.3%
Income quality (OCF / net income)1.27———0.721.651.051.381.211.49
Financial health
Total debt$2.55B$2.62B$2.26B$3.56B$2.54B$1.91B$1.88B$2.00B$1.19B$1.05B
Cash & short-term investments$1.63B$1.22B$1.05B$2.04B$1.34B$3.47B$3.41B$3.51B$2.15B$1.56B
Net debt$920.0M$1.40B$1.21B$1.52B$1.20B−$1.57B−$1.53B−$1.51B−$953.0M−$509.7M
Debt / equity0.941.100.390.540.240.410.410.520.420.46
Debt / assets0.380.420.220.290.170.250.260.290.230.25
Net debt / EBITDA0.63———9.38−2.70−1.31−1.43−1.25−0.69
Current ratio2.081.781.661.282.483.606.692.493.993.29
Quick ratio1.721.421.291.082.093.306.152.273.552.86
Interest coverage8.6-8.3-13.9-160.7-2.08.018.915.516.417.8
Working capital$1.70B$1.20B$1.04B$788.0M$1.62B$3.24B$3.79B$2.69B$2.23B$1.61B
Invested capital$3.64B$3.77B$6.95B$8.12B$11.94B$3.13B$3.08B$2.33B$1.89B$1.76B
Tangible asset value$1.40B$965.0M$207.0M$75.0M$377.0M$3.65B$3.64B$2.89B$2.02B$1.30B
Net current asset value−$632.0M−$1.18B−$1.76B−$2.09B−$1.76B$1.59B$1.75B$1.44B$692.0M$351.7M
Graham number$46.26———$89.87$56.24$68.44$56.73$46.05$32.85
Graham net-net per share−$8.75−$11.78−$15.53−$17.94−$16.06$7.65$8.86$6.96$2.24$0.19
Capital allocation
Dividends paid———$937.0M$511.0M——$735.0M$5.0M$11.6M
Share buybacks (net)$742.0M$116.0M$40.0M$54.0M$511.0M$736.0M$324.0M$201.0M$251.0M$249.0M
Dividend payout ratio————67.1%——89.0%0.7%2.5%
Dividends + buybacks / free cash flow79.7%16.4%14.2%934.9%303.3%82.6%38.5%110.6%45.5%62.7%
Capex / revenue3.4%2.9%4.3%6.2%4.6%5.8%5.9%8.9%11.3%11.3%
Capex / operating cash flow13.7%15.3%40.8%73.0%38.2%17.5%19.9%25.9%35.7%39.5%
Capex / depreciation0.550.360.450.730.831.011.111.652.001.92
Stock-based compensation / revenue6.3%8.5%8.4%8.0%16.7%6.0%5.5%5.8%6.0%5.4%
R&D / revenue21.9%26.7%30.1%28.8%26.2%21.1%18.3%18.7%19.8%21.0%
SG&A / revenue23.8%25.0%35.8%28.3%46.2%29.1%23.6%23.8%24.5%24.3%
Efficiency
Days sales outstanding67.562.758.353.846.459.756.050.652.558.4
Days of inventory on hand140.3137.0119.8113.1106.8128.8126.4127.0124.8142.3
Days payables outstanding58.256.355.870.869.760.156.560.858.769.1
Cash conversion cycle (days)149.6143.4122.396.283.5128.4125.9116.9118.6131.6
Receivables turnover5.415.826.266.787.866.116.527.216.956.26
Payables turnover6.276.486.545.165.246.086.466.016.215.28
Inventory turnover2.602.663.053.233.422.832.892.872.922.56
Asset turnover0.670.530.400.330.400.430.500.550.580.60
Average receivables$802.5M$751.5M$720.0M$676.0M$575.5M$530.0M$543.5M$462.5M$396.2M$383.4M
Average payables$230.5M$233.0M$269.0M$312.5M$262.0M$170.5M$166.5M$172.0M$149.0M$138.6M
Average inventory$555.5M$567.0M$577.5M$499.5M$401.5M$365.5M$372.5M$359.5M$316.6M$285.5M
Intangibles / total assets19.9%22.3%54.8%53.2%68.1%13.7%13.2%14.6%18.0%23.8%

Computed from ILMN's annual financial statements (latest annual report filed February 12, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

ILMN valuation and financial ratios

At the end of fiscal 2025 (December 31, 2025), Illumina traded at 24.1 times earnings, against a 10-year median of 48.0. Based on the latest twelve months, the trailing P/E is 49.0 and the forward P/E is 40.3. Illumina earned a return on equity of 33.4% and a return on invested capital of 18.2% in fiscal 2025. It ended the year with $2.6 billion of debt and $1.6 billion in cash and short-term investments, net debt of $920.0 million. It returned $742.0 million to shareholders: $0 in dividends and $742.0 million in share buybacks, 80% of free cash flow. The share count rose 5.4% from 148.0M to 156.0M over 9 years.

See the ILMN income statement, the ILMN chart for price history, or the ILMN stock overview for the latest quote and news.

ILMN key metrics FAQ

What is Illumina's P/E ratio?

Illumina's trailing P/E ratio is 49.0 based on the last twelve months of earnings (as of October 18, 2026), and its forward P/E is 40.3. At the end of fiscal 2025 it was 24.1, compared with a 10-year median of 48.0.

What is Illumina's EV/EBITDA?

Illumina's enterprise value was 14.7 times EBITDA at the end of fiscal 2025 (enterprise value $21.4 billion, EBITDA $1.5 billion); the current EV/EBITDA is 28.0.

What is Illumina's return on equity?

Illumina's return on equity (ROE) was 33.4% in fiscal 2025: net income of $850.0 million on average shareholders' equity of $2.5 billion.

What is Illumina's ROIC?

Illumina's return on invested capital was 18.2% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does Illumina have?

Illumina had total debt of $2.6 billion at the end of fiscal 2025, a debt-to-equity ratio of 0.94 and $920.0 million of net debt (0.63 times EBITDA).

Does Illumina buy back its shares?

Yes. Illumina spent $742.0 million on net share repurchases in fiscal 2025 Shares outstanding changed −1.9% over the year, to 156.0M..

What is Illumina's free cash flow yield?

Illumina generated $931.0 million of free cash flow in fiscal 2025, a free cash flow yield of 4.6% on its market value at year-end ($20.5 billion).

What is Illumina's current ratio?

Illumina's current ratio was 2.08 at the end of fiscal 2025: current assets were 2.08 times current liabilities.

Diagnostics & Research key metrics