Exelixis, Inc. (EXEL) Key Metrics
EXEL valuation today
Trailing 12 months · as of October 18, 2026- Market cap
- $15.42B
- Enterprise value
- $13.38B
- P/E (TTM)
- 19.6 10-yr median 25.5
- Forward P/E
- 13.6
- PEG ratio
- 2.27
- Price / sales
- 6.3 10-yr median 5.5
- Price / book
- 7.8 10-yr median 3.9
- EV / EBITDA
- 13.1 10-yr median 14.9
- Dividend yield
- —
- Beta
- 0.47
EXEL key metrics, 2016–2025
Fiscal year ended December 31, 2025 · U.S. dollarsEXEL valuation Price multiples at each fiscal year-end price.
EXEL returns How much profit the business earns on the capital it uses.
EXEL per-share figures Results divided by the shares outstanding at year-end.
EXEL financial health Debt, liquidity and how easily interest is covered.
EXEL efficiency & capital use Working capital cycle and where the cash goes.
EXEL valuation history
EXEL returns on capital
Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.
EXEL debt vs cash
Debt includes short- and long-term borrowings and, where reported, lease liabilities.
EXEL cash returned to shareholders
EXEL price vs earnings per share
EXEL key metrics
2016–2025| 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Valuation | ||||||||||
| Market capitalization | $12.35B | $9.86B | $7.71B | $5.21B | $5.89B | $6.38B | $5.55B | $6.15B | $9.48B | $3.74B |
| Enterprise value | $11.47B | $8.94B | $6.91B | $4.09B | $4.48B | $5.22B | $4.75B | $5.52B | $9.17B | $3.50B |
| P/E ratio | 15.8 | 18.9 | 37.1 | 28.6 | 25.5 | 57.1 | 17.3 | 8.9 | 61.5 | — |
| Price / sales | 5.3 | 4.5 | 4.2 | 3.2 | 4.1 | 6.5 | 5.7 | 7.2 | 21.0 | 19.5 |
| Price / book | 5.7 | 4.4 | 3.4 | 2.1 | 2.7 | 3.4 | 3.3 | 4.8 | 33.3 | 41.8 |
| Price / free cash flow | 14.6 | 15.6 | 45.3 | 23.2 | 17.5 | 35.7 | 10.8 | 16.1 | 65.7 | 18.3 |
| Price / operating cash flow | 14.0 | 14.1 | 23.1 | 14.4 | 14.7 | 30.5 | 10.5 | 14.8 | 57.3 | 18.1 |
| EV / sales | 4.9 | 4.1 | 3.8 | 2.5 | 3.1 | 5.3 | 4.9 | 6.5 | 20.3 | 18.3 |
| EV / EBITDA | 12.4 | 12.4 | 24.4 | 18.4 | 14.9 | 43.8 | 12.6 | 12.2 | 54.8 | — |
| EV / free cash flow | 13.6 | 14.1 | 40.5 | 18.2 | 13.3 | 29.2 | 9.2 | 14.4 | 63.5 | 17.1 |
| Earnings yield | 6.3% | 5.3% | 2.7% | 3.5% | 3.9% | 1.8% | 5.8% | 11.2% | 1.6% | −1.9% |
| Free cash flow yield | 6.8% | 6.4% | 2.2% | 4.3% | 5.7% | 2.8% | 9.3% | 6.2% | 1.5% | 5.5% |
| Dividend yield | — | — | — | — | — | — | — | — | 0.0% | 0.0% |
| Shareholder yield (dividends + buybacks) | 7.7% | 6.6% | 7.1% | 0.0% | 0.7% | 0.8% | 0.2% | 0.1% | 0.1% | 0.1% |
| Share price at fiscal year-end | $43.83 | $33.30 | $23.99 | $16.04 | $18.28 | $20.07 | $17.62 | $19.67 | $30.40 | $14.91 |
| Per share | ||||||||||
| Revenue per share | $8.23 | $7.32 | $5.69 | $4.96 | $4.45 | $3.11 | $3.07 | $2.73 | $1.45 | $0.76 |
| Earnings per share | $2.78 | $1.76 | $0.65 | $0.56 | $0.72 | $0.35 | $1.02 | $2.21 | $0.49 | −$0.28 |
| Operating cash flow per share | $3.14 | $2.36 | $1.04 | $1.12 | $1.24 | $0.66 | $1.67 | $1.33 | $0.53 | $0.82 |
| Free cash flow per share | $3.00 | $2.14 | $0.53 | $0.69 | $1.04 | $0.56 | $1.63 | $1.22 | $0.46 | $0.82 |
| Cash per share | $3.76 | $3.75 | $3.10 | $4.03 | $4.55 | $3.79 | $2.71 | $2.22 | $1.24 | $1.68 |
| Book value per share | $7.67 | $7.58 | $7.04 | $7.67 | $6.86 | $5.91 | $5.35 | $4.12 | $0.91 | $0.36 |
| Tangible book value per share | $7.44 | $7.36 | $6.84 | $7.47 | $6.66 | $5.71 | $5.15 | $3.91 | $0.51 | −$0.15 |
| Dividends per share | — | — | — | — | — | — | — | — | $0.00 | $0.00 |
| Capex per share | $0.14 | $0.22 | $0.51 | $0.43 | $0.20 | $0.10 | $0.04 | $0.11 | $0.07 | $0.01 |
| Debt per share | $0.61 | $0.64 | $0.59 | $0.59 | $0.16 | $0.15 | $0.16 | $0.18 | $0.23 | $0.75 |
| Shares outstanding | 281.9M | 296.1M | 321.5M | 324.6M | 322.4M | 318.0M | 315.0M | 312.8M | 312.0M | 250.5M |
| Change in shares outstanding | −4.8% | −7.9% | −1.0% | +0.7% | +1.4% | +0.9% | +0.7% | +0.3% | +24.5% | +19.7% |
| Returns & profitability | ||||||||||
| Return on equity (ROE) | 35.5% | 23.1% | 8.7% | 7.8% | 11.3% | 6.3% | 21.6% | 87.8% | 82.4% | — |
| Return on invested capital (ROIC) | 55.8% | 33.2% | 9.7% | 14.5% | 29.7% | 11.7% | 38.8% | 141.5% | — | — |
| Return on assets (ROA) | 27.0% | 17.7% | 6.9% | 6.4% | 9.7% | 5.6% | 19.4% | 66.4% | 24.6% | −15.1% |
| Return on tangible assets | 28.1% | 18.1% | 7.2% | 6.1% | 9.1% | 5.4% | 17.6% | 50.8% | 29.2% | −14.9% |
| Free cash flow margin | 36.4% | 29.2% | 9.3% | 13.9% | 23.5% | 18.1% | 53.1% | 44.8% | 31.9% | 106.9% |
| Income quality (OCF / net income) | 1.13 | 1.34 | 1.60 | 1.99 | 1.73 | 1.87 | 1.64 | 0.60 | 1.07 | — |
| Financial health | ||||||||||
| Total debt | $173.0M | $190.8M | $189.9M | $190.2M | $51.3M | $49.1M | $50.7M | $56.9M | $72.0M | $189.1M |
| Cash & short-term investments | $1.06B | $1.11B | $995.3M | $1.31B | $1.47B | $1.21B | $852.2M | $693.3M | $387.8M | $419.8M |
| Net debt | −$886.1M | −$920.5M | −$805.4M | −$1.12B | −$1.42B | −$1.16B | −$801.5M | −$636.4M | −$315.8M | −$230.7M |
| Debt / equity | 0.08 | 0.09 | 0.08 | 0.08 | 0.02 | 0.03 | 0.03 | 0.04 | 0.25 | 2.12 |
| Debt / assets | 0.06 | 0.06 | 0.06 | 0.06 | 0.02 | 0.02 | 0.03 | 0.04 | 0.11 | 0.32 |
| Net debt / EBITDA | −0.96 | −1.28 | −2.84 | −5.03 | −4.71 | −9.71 | −2.12 | −1.41 | −1.89 | — |
| Current ratio | 3.56 | 3.63 | 3.34 | 4.99 | 5.43 | 7.06 | 7.08 | 8.50 | 4.21 | 1.74 |
| Quick ratio | 3.50 | 3.58 | 3.30 | 4.89 | 5.35 | 6.96 | 6.99 | 8.41 | 4.15 | 1.73 |
| Interest coverage | — | — | — | 3.7 | — | — | — | — | 19.1 | -0.9 |
| Working capital | $1.04B | $1.06B | $923.7M | $1.29B | $1.50B | $1.24B | $868.4M | $791.5M | $369.7M | $200.2M |
| Invested capital | $1.28B | $1.32B | $1.46B | $1.37B | $794.8M | $721.7M | $884.5M | $651.0M | −$30.8M | −$141.4M |
| Tangible asset value | $2.10B | $2.18B | $2.20B | $2.42B | $2.15B | $1.82B | $1.62B | $1.22B | $157.6M | −$38.0M |
| Net current asset value | $760.2M | $764.1M | $639.5M | $1.04B | $1.43B | $1.19B | $811.5M | $762.2M | $114.5M | −$37.4M |
| Graham number | $21.89 | $17.32 | $10.12 | $9.84 | $10.52 | $6.84 | $11.08 | $14.29 | $3.19 | — |
| Graham net-net per share | $2.14 | $2.09 | $1.57 | $2.78 | $3.99 | $3.39 | $2.38 | $2.23 | $0.26 | −$0.23 |
| Capital allocation | ||||||||||
| Dividends paid | — | — | — | — | — | — | — | — | $0 | $0 |
| Share buybacks (net) | $947.5M | $652.0M | $550.4M | $0 | $39.1M | $50.0M | $9.9M | $7.6M | $6.6M | $4.1M |
| Dividend payout ratio | — | — | — | — | — | — | — | — | 0.0% | — |
| Dividends + buybacks / free cash flow | 112.2% | 102.9% | 323.1% | 0.0% | 11.6% | 28.0% | 1.9% | 2.0% | 4.5% | 2.0% |
| Capex / revenue | 1.7% | 3.1% | 8.9% | 8.6% | 4.5% | 3.1% | 1.3% | 3.9% | 4.7% | 0.9% |
| Capex / operating cash flow | 4.5% | 9.5% | 48.9% | 38.2% | 16.0% | 14.5% | 2.4% | 8.0% | 12.8% | 0.8% |
| Capex / depreciation | 1.37 | 2.30 | 6.34 | 6.63 | 4.71 | 3.32 | 1.54 | 4.29 | 17.81 | 1.70 |
| Stock-based compensation / revenue | 4.9% | 4.3% | 5.8% | 6.7% | 8.4% | 10.6% | 5.8% | 5.2% | 5.3% | 12.0% |
| R&D / revenue | 35.6% | 42.0% | 57.0% | 55.4% | 48.3% | 55.5% | 34.8% | 21.3% | 24.8% | 50.1% |
| SG&A / revenue | 22.4% | 22.7% | 29.7% | 28.5% | 28.0% | 29.7% | 23.6% | 24.2% | 35.2% | 60.7% |
| Efficiency | ||||||||||
| Days sales outstanding | 43.4 | 42.3 | 45.1 | 56.3 | 56.4 | 51.7 | 56.2 | 55.6 | 49.1 | 43.5 |
| Days of inventory on hand | 96.1 | 95.1 | 127.3 | 191.6 | 167.3 | 170.4 | 125.3 | 114.3 | 121.1 | 165.8 |
| Days payables outstanding | 147.9 | 172.3 | 167.1 | 179.4 | 165.3 | 177.2 | 124.0 | 141.8 | 195.5 | 361.2 |
| Cash conversion cycle (days) | -8.3 | -34.9 | 5.3 | 68.5 | 58.4 | 44.9 | 57.5 | 28.0 | -25.4 | -151.8 |
| Receivables turnover | 8.40 | 8.63 | 8.09 | 6.48 | 6.47 | 7.06 | 6.50 | 6.57 | 7.44 | 8.39 |
| Payables turnover | 2.47 | 2.12 | 2.18 | 2.03 | 2.21 | 2.06 | 2.94 | 2.57 | 1.87 | 1.01 |
| Inventory turnover | 3.80 | 3.84 | 2.87 | 1.91 | 2.18 | 2.14 | 2.91 | 3.19 | 3.01 | 2.20 |
| Asset turnover | 0.80 | 0.74 | 0.61 | 0.57 | 0.60 | 0.49 | 0.59 | 0.82 | 0.72 | 0.41 |
| Average receivables | $276.2M | $251.4M | $226.1M | $248.7M | $221.8M | $140.0M | $148.9M | $130.0M | $60.8M | $22.8M |
| Average payables | $33.9M | $36.0M | $33.2M | $28.5M | $23.9M | $17.6M | $11.2M | $10.2M | $8.1M | $6.5M |
| Average inventory | $22.0M | $19.9M | $25.3M | $30.4M | $24.2M | $16.9M | $11.4M | $8.2M | $5.0M | $3.0M |
| Intangibles / total assets | 2.2% | 2.2% | 2.2% | 2.1% | 2.4% | 3.0% | 3.4% | 4.5% | 19.4% | 21.3% |
Computed from EXEL's annual financial statements (latest annual report filed February 10, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.
EXEL valuation and financial ratios
At the end of fiscal 2025 (December 31, 2025), Exelixis traded at 15.8 times earnings, against a 10-year median of 25.5. Based on the latest twelve months, the trailing P/E is 19.6 and the forward P/E is 13.6. Exelixis earned a return on equity of 35.5% and a return on invested capital of 55.8% in fiscal 2025. It ended the year with $173.0 million of debt and $1.1 billion in cash and short-term investments, a net cash position of $886.1 million. It returned $947.5 million to shareholders: $0 in dividends and $947.5 million in share buybacks, 112% of free cash flow. The share count rose 12.5% from 250.5M to 281.9M over 9 years.
See the EXEL income statement, the EXEL chart for price history, or the EXEL stock overview for the latest quote and news.
EXEL key metrics FAQ
What is Exelixis's P/E ratio?
Exelixis's trailing P/E ratio is 19.6 based on the last twelve months of earnings (as of October 18, 2026), and its forward P/E is 13.6. At the end of fiscal 2025 it was 15.8, compared with a 10-year median of 25.5.
What is Exelixis's EV/EBITDA?
Exelixis's enterprise value was 12.4 times EBITDA at the end of fiscal 2025 (enterprise value $11.5 billion, EBITDA $921.8 million); the current EV/EBITDA is 13.1.
What is Exelixis's return on equity?
Exelixis's return on equity (ROE) was 35.5% in fiscal 2025: net income of $782.6 million on average shareholders' equity of $2.2 billion.
What is Exelixis's ROIC?
Exelixis's return on invested capital was 55.8% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.
How much debt does Exelixis have?
Exelixis had total debt of $173.0 million at the end of fiscal 2025, a debt-to-equity ratio of 0.08 and more cash than debt.
Does Exelixis buy back its shares?
Yes. Exelixis spent $947.5 million on net share repurchases in fiscal 2025 Shares outstanding changed −4.8% over the year, to 281.9M..
What is Exelixis's free cash flow yield?
Exelixis generated $844.3 million of free cash flow in fiscal 2025, a free cash flow yield of 6.8% on its market value at year-end ($12.4 billion).
What is Exelixis's current ratio?
Exelixis's current ratio was 3.56 at the end of fiscal 2025: current assets were 3.56 times current liabilities.