Cue Biopharma, Inc. (CUE) Key Metrics

NASDAQ: CUEValuation, returns, debt and efficiency ratios over 10 years.

CUE valuation today

Trailing 12 months · as of October 17, 2026
Market cap
$121.4M
Enterprise value
$214.9M
P/E (TTM)
—
Forward P/E
—
PEG ratio
—
Price / sales
3.2
10-yr median 6.6
Price / book
99.2
10-yr median 3.3
EV / EBITDA
—
Dividend yield
—
Beta
2.63

CUE key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

CUE valuation Price multiples at each fiscal year-end price.

Price / sales−84.1%
1.1
2025 · hover or tap a bar for each year
2023: 22.02024: 6.6 (−70.0%)2025: 1.1 (−84.1%)
20162025
Price / book−68.8%
1.1
2025 · hover or tap a bar for each year
2023: 3.32024: 3.5 (+7.7%)2025: 1.1 (−68.8%)
20162025
Free cash flow yield−16.3 pts
−75.6%
2025 · hover or tap a bar for each year
2023: −33.1%2024: −59.3% (−26.2 pts)2025: −75.6% (−16.3 pts)
20162025

CUE valuation history

Fiscal year-endToday10-year median

CUE returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

CUE debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

CUE cash returned to shareholders

DividendsBuybacksFree cash flow

CUE price vs earnings per share

Share price at year-endEPS (right axis)

CUE key metrics

2016–2025
Cue Biopharma, Inc. key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$28.9M$61.4M$120.8M———————
Enterprise value$6.0M$47.8M$87.0M———————
Price / sales1.16.622.0———————
Price / book1.13.53.3———————
EV / sales0.25.115.8———————
Earnings yield−91.9%−66.2%−42.0%———————
Free cash flow yield−75.6%−59.3%−33.1%———————
Share price at fiscal year-end$9.16$32.70$79.20$85.50$339.30$375.30$476.25$141.00——
Per share
Revenue per share$8.70$4.95$3.60———————
Earnings per share−$8.42−$21.66−$33.26———————
Operating cash flow per share−$6.87−$19.35−$26.20———————
Free cash flow per share−$6.92−$19.38−$26.20———————
Cash per share$8.59$11.96$31.81———————
Book value per share$8.37$9.32$24.32———————
Tangible book value per share$8.37$9.32$24.32———————
Capex per share$0.06$0.04$0.00———————
Debt per share$1.33$4.73$9.64———————
Shares outstanding3.2M1.9M1.5M———————
Change in shares outstanding+68.2%+23.1%————————
Returns & profitability
Return on equity (ROE)−121.1%−149.0%−98.7%−80.8%−61.2%−67.1%−82.9%−81.6%−60.5%−69.3%
Return on invested capital (ROIC)−565.6%−913.0%−688.1%−384.9%−481.9%—————
Return on assets (ROA)−71.5%−86.8%−66.4%−60.7%−48.3%−52.3%−62.7%−69.4%−55.8%−64.9%
Return on tangible assets−63.0%−126.4%−82.5%−58.1%−53.0%−45.0%−51.3%−85.9%−34.8%−47.0%
Free cash flow margin−79.6%−391.9%−727.9%—−266.0%—−891.9%———
Financial health
Total debt$4.2M$8.9M$14.7M$19.3M$12.0M$7.1M$5.8M—$2.5M—
Cash & short-term investments$27.1M$22.5M$48.5M$76.3M$64.4M$84.9M$59.4M$39.2M$63.6M$15.0M
Net debt−$22.9M−$13.6M−$33.8M−$57.0M−$52.3M−$77.7M−$53.6M−$39.2M−$61.1M−$15.0M
Debt / equity0.160.510.400.290.180.090.11—0.04—
Debt / assets0.100.280.240.210.140.070.08—0.04—
Current ratio2.741.843.016.685.355.365.246.5312.1714.18
Quick ratio2.741.843.016.685.355.363.946.5312.1314.18
Interest coverage-74.3-52.1-41.9-74.6-25.2-97.1-6.5———
Working capital$23.5M$11.4M$34.4M$65.6M$55.7M$71.2M$49.4M$34.4M$59.7M$14.1M
Invested capital$3.5M$3.9M$3.3M$8.7M$13.1M$1.2M$969,699−$5.2M$523,461$198,787
Tangible asset value$26.4M$17.5M$37.1M$65.7M$65.5M$78.9M$54.6M$34.0M$61.4M$15.2M
Net current asset value$21.2M$10.4M$27.0M$51.6M$50.6M$66.9M$44.0M$29.2M$59.7M$14.0M
Graham net-net per share$5.36$4.51$16.62———————
Capital allocation
Dividends paid———$199,873——————
Share buybacks (net)———$200,000$750,128$271,051$91,027$0$4.2M$1.4M
Capex / revenue0.6%0.7%0.0%13.7%6.1%18.9%1.3%162.3%——
Capex / depreciation0.180.030.000.09—0.560.062.442.872.55
Stock-based compensation / revenue17.3%73.7%149.0%762.7%77.1%332.3%188.6%627.8%——
R&D / revenue137.4%390.8%743.2%3,098.6%276.7%1,063.5%794.9%2,498.2%——
SG&A / revenue59.1%157.0%303.8%1,298.7%115.8%464.5%368.4%988.5%——
Efficiency
Days sales outstanding55.751.958.3469.055.7125.779.7———
Days of inventory on hand——0.00.0-0.0—200.8—196.2—
Days payables outstanding355.1491.129.9537.8-478.416.119.421.5806.0599.1
Cash conversion cycle (days)-299.3-439.228.5-68.7534.1109.6261.1———
Receivables turnover6.557.036.260.786.552.904.58—0.00—
Payables turnover1.030.7412.230.68−0.7622.7218.8416.970.450.61
Inventory turnover——38,097,000.001,806,055.00−1,777,985.00—1.82—1.86—
Asset turnover0.740.200.070.010.160.040.060.020.000.00
Average receivables$4.2M$1.3M$877,500$1.6M$2.3M$1.1M$754,898—$852,376—
Average payables$3.4M$3.2M$3.1M$2.7M$2.3M$1.5M$1.5M$1.7M$926,468$331,722
Average inventory——$1$1$1—$15.1M—$225,500—
Intangibles / total assets0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.3%0.0%

Computed from CUE's annual financial statements (latest annual report filed March 16, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

CUE valuation and financial ratios

Cue Biopharma earned a return on equity of −121.1% and a return on invested capital of −565.6% in fiscal 2025. It ended the year with $4.2 million of debt and $27.1 million in cash and short-term investments, a net cash position of $22.9 million.

See the CUE income statement, the CUE chart for price history, or the CUE stock overview for the latest quote and news.

CUE key metrics FAQ

What is Cue Biopharma's return on equity?

Cue Biopharma's return on equity (ROE) was −121.1% in fiscal 2025: net income of -$26.6 million on average shareholders' equity of $22.0 million.

What is Cue Biopharma's ROIC?

Cue Biopharma's return on invested capital was −565.6% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does Cue Biopharma have?

Cue Biopharma had total debt of $4.2 million at the end of fiscal 2025, a debt-to-equity ratio of 0.16 and more cash than debt.

What is Cue Biopharma's free cash flow yield?

Cue Biopharma generated -$21.9 million of free cash flow in fiscal 2025, a free cash flow yield of −75.6% on its market value at year-end ($28.9 million).

What is Cue Biopharma's current ratio?

Cue Biopharma's current ratio was 2.74 at the end of fiscal 2025: current assets were 2.74 times current liabilities.

Biotechnology key metrics