AstraZeneca PLC (AZN) Key Metrics

NYSE: AZNValuation, returns, debt and efficiency ratios over 10 years.

AZN valuation today

Trailing 12 months · as of October 18, 2026
Market cap
$256.54B
Enterprise value
$290.01B
P/E (TTM)
23.8
10-yr median 35.3
Forward P/E
14.6
PEG ratio
1.18
Price / sales
4.2
10-yr median 4.5
Price / book
5.2
10-yr median 5.8
EV / EBITDA
14.2
10-yr median 16.5
Dividend yield
1.93%
$3.20 a year
Beta
0.21

AZN key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

AZN valuation Price multiples at each fiscal year-end price.

P/E ratio−3.8%
28.0
2025 · hover or tap a bar for each year
2016: 19.8 (−35.0%)2017: 29.3 (+48.2%)2018: 44.7 (+52.4%)2019: 97.2 (+117.6%)2020: 41.1 (−57.7%)2022: 64.32023: 35.3 (−45.1%)2024: 29.1 (−17.6%)2025: 28.0 (−3.8%)
20162025
Price / sales+29.1%
4.9
2025 · hover or tap a bar for each year
2016: 3.0 (−13.5%)2017: 3.9 (+30.2%)2018: 4.4 (+11.3%)2019: 5.3 (+22.1%)2020: 4.9 (−7.3%)2021: 4.4 (−9.9%)2022: 4.8 (+7.3%)2023: 4.6 (−3.7%)2024: 3.8 (−17.5%)2025: 4.9 (+29.1%)
20162025
Price / book+17.5%
5.9
2025 · hover or tap a bar for each year
2016: 4.7 (+0.2%)2017: 5.9 (+26.2%)2018: 7.7 (+31.3%)2019: 9.9 (+28.0%)2020: 8.4 (−15.0%)2021: 4.2 (−49.6%)2022: 5.7 (+34.9%)2023: 5.4 (−5.9%)2024: 5.0 (−6.6%)2025: 5.9 (+17.5%)
20162025
EV / EBITDA+5.6%
15.7
2025 · hover or tap a bar for each year
2016: 11.0 (−18.6%)2017: 15.3 (+38.8%)2018: 15.4 (+0.9%)2019: 21.1 (+36.9%)2020: 17.8 (−15.8%)2021: 37.3 (+109.7%)2022: 25.8 (−30.8%)2023: 17.4 (−32.7%)2024: 14.9 (−14.5%)2025: 15.7 (+5.6%)
20162025
Price / free cash flow+17.7%
33.1
2025 · hover or tap a bar for each year
2016: 37.8 (−76.4%)2017: 44.9 (+18.9%)2018: 77.2 (+71.9%)2019: 254.9 (+230.3%)2020: 59.9 (−76.5%)2021: 44.2 (−26.2%)2022: 29.2 (−33.8%)2023: 32.0 (+9.6%)2024: 28.2 (−12.1%)2025: 33.1 (+17.7%)
20162025
Free cash flow yield−0.5 pts
3.0%
2025 · hover or tap a bar for each year
2016: 2.6% (+2.0 pts)2017: 2.2% (−0.4 pts)2018: 1.3% (−0.9 pts)2019: 0.4% (−0.9 pts)2020: 1.7% (+1.3 pts)2021: 2.3% (+0.6 pts)2022: 3.4% (+1.2 pts)2023: 3.1% (−0.3 pts)2024: 3.6% (+0.4 pts)2025: 3.0% (−0.5 pts)
20162025

AZN valuation history

Fiscal year-endToday10-year median

AZN returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

AZN debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

AZN cash returned to shareholders

DividendsBuybacksFree cash flow

AZN price vs earnings per share

Share price at year-endEPS (right axis)

AZN key metrics

2016–2025
AstraZeneca PLC key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$287.19B$204.82B$210.40B$211.54B$166.25B$131.27B$129.74B$96.24B$87.93B$69.17B
Enterprise value$311.15B$229.40B$233.16B$234.44B$190.54B$143.66B$141.75B$109.67B$101.18B$80.08B
P/E ratio28.029.135.364.3—41.197.244.729.319.8
Price / sales4.93.84.64.84.44.95.34.43.93.0
Price / book5.95.05.45.74.28.49.97.75.94.7
Price / free cash flow33.128.232.029.244.259.9254.977.244.937.8
Price / operating cash flow19.717.320.321.627.927.443.736.824.616.7
EV / sales5.34.25.15.35.15.45.85.04.53.5
EV / EBITDA15.714.917.425.837.317.821.115.415.311.0
EV / free cash flow35.931.535.532.450.665.5278.588.051.743.7
Earnings yield3.6%3.4%2.8%1.6%0.1%2.4%1.0%2.2%3.4%5.1%
Free cash flow yield3.0%3.6%3.1%3.4%2.3%1.7%0.4%1.3%2.2%2.6%
Dividend yield1.7%2.3%2.1%2.1%2.3%2.7%2.8%3.6%4.0%5.1%
Shareholder yield (dividends + buybacks)2.0%2.3%2.1%2.1%2.3%2.7%2.8%3.6%4.0%5.1%
Share price at fiscal year-end$183.86$131.04$134.70$135.60$116.50$99.98$99.72$75.96$69.40$54.64
Per share
Revenue per share$37.60$34.60$29.33$28.43$26.22$20.27$18.74$17.43$17.73$18.17
Earnings per share$6.57$4.50$3.81$2.11$0.08$2.43$1.03$1.70$2.37$2.76
Operating cash flow per share$9.33$7.59$6.62$6.29$4.18$3.65$2.28$2.07$2.82$3.27
Free cash flow per share$5.55$4.65$4.20$4.64$2.64$1.67$0.39$0.98$1.55$1.45
Cash per share$3.68$3.53$3.75$4.00$4.48$6.09$4.78$4.48$3.59$4.66
Book value per share$31.16$26.09$25.06$23.74$27.52$11.90$10.09$9.84$11.81$11.73
Tangible book value per share−$6.67−$11.14−$12.16−$14.16−$16.20−$13.08−$14.89−$16.73−$18.19−$19.27
Dividends per share$3.18$2.96$2.87$2.80$2.70$2.72$2.76$2.75$2.78$2.81
Capex per share$3.78$2.93$2.42$1.65$1.54$1.98$1.89$1.08$1.28$1.83
Debt per share$19.02$19.27$18.32$18.68$21.51$15.52$14.01$15.09$14.05$13.28
Shares outstanding1.56B1.56B1.56B1.56B1.43B1.31B1.30B1.27B1.27B1.27B
Change in shares outstanding−0.1%+0.1%+0.1%+9.3%+8.7%+0.9%+2.7%0.0%+0.1%+0.1%
Returns & profitability
Return on equity (ROE)22.9%17.6%15.6%8.6%0.4%22.2%10.4%15.7%20.1%21.0%
Return on invested capital (ROIC)16.4%12.7%11.6%6.1%1.8%15.6%9.1%12.5%13.6%17.9%
Return on assets (ROA)9.4%6.9%6.0%3.3%0.1%5.0%2.2%3.5%4.8%5.7%
Return on tangible assets18.7%15.3%13.9%8.8%0.3%9.4%4.6%8.0%11.8%15.0%
Free cash flow margin14.8%13.5%14.3%16.3%10.1%8.2%2.1%5.6%8.7%8.0%
Income quality (OCF / net income)1.421.691.742.9853.241.502.221.211.191.18
Financial health
Total debt$29.70B$30.11B$28.62B$29.14B$30.69B$20.38B$18.23B$19.11B$17.81B$16.81B
Cash & short-term investments$5.74B$5.53B$5.86B$6.24B$6.40B$7.99B$6.22B$5.68B$4.55B$5.90B
Net debt$23.96B$24.59B$22.76B$22.90B$24.29B$12.39B$12.01B$13.43B$13.25B$10.91B
Debt / equity0.610.740.730.790.781.301.391.531.191.13
Debt / assets0.260.290.280.300.290.310.300.320.280.27
Net debt / EBITDA1.211.591.702.524.751.531.791.892.001.50
Current ratio0.940.930.820.861.160.960.860.960.800.87
Quick ratio0.720.740.640.680.760.760.680.780.620.72
Interest coverage8.15.95.22.80.84.12.12.52.73.6
Working capital−$1.89B−$2.04B−$5.49B−$3.70B$3.65B−$763.0M−$2.55B−$701.0M−$3.23B−$1.99B
Invested capital$72.63B$65.38B$61.91B$59.94B$63.56B$28.01B$25.14B$25.90B$28.21B$25.76B
Tangible asset value−$10.37B−$17.33B−$18.97B−$22.07B−$23.10B−$17.15B−$17.91B−$19.62B−$21.37B−$22.57B
Net current asset value−$36.63B−$37.34B−$36.90B−$36.83B−$39.83B−$31.55B−$31.22B−$31.02B−$33.56B−$32.59B
Graham number$67.84$51.41$46.36$33.55$6.97$25.53$15.26$19.41$25.08$27.01
Graham net-net per share−$28.78−$29.79−$30.14−$28.17−$34.40−$28.06−$27.13−$29.39−$30.42−$29.11
Capital allocation
Dividends paid$4.97B$4.63B$4.48B$4.36B$3.86B$3.57B$3.59B$3.48B$3.52B$3.56B
Share buybacks (net)$719.7M$43.0M$0———————
Dividend payout ratio48.5%65.8%75.2%132.7%—111.8%269.1%161.7%117.3%101.8%
Dividends + buybacks / free cash flow65.6%64.2%68.2%60.3%102.5%162.9%705.7%279.4%179.7%194.5%
Capex / revenue10.1%8.5%8.2%5.8%5.9%9.8%10.1%6.2%7.2%10.1%
Capex / operating cash flow40.5%38.7%36.5%26.2%36.9%54.3%82.9%52.4%45.3%55.8%
Capex / depreciation1.030.910.770.490.340.830.650.370.530.98
Stock-based compensation / revenue——1.3%1.4%1.6%1.0%1.1%———
R&D / revenue24.2%25.1%23.9%22.0%26.0%22.5%24.8%26.9%25.6%25.6%
SG&A / revenue34.9%37.4%39.8%40.5%40.5%44.7%49.2%49.7%45.6%40.9%
Efficiency
Days sales outstanding82.166.370.171.367.272.359.147.943.757.3
Days of inventory on hand203.3191.5223.4201.5190.9248.6225.6219.1226.9198.0
Days payables outstanding496.4123.5128.479.275.9142.0129.6148.1167.6227.7
Cash conversion cycle (days)-211.0134.3165.2193.7182.2178.8155.1118.9103.127.5
Receivables turnover4.455.515.215.125.435.056.187.628.346.38
Payables turnover0.742.962.844.614.812.572.822.462.181.60
Inventory turnover1.801.911.631.811.911.471.621.671.611.84
Asset turnover0.540.530.460.440.430.420.400.360.360.38
Average receivables$13.21B$9.82B$8.80B$8.66B$6.89B$5.27B$3.95B$2.90B$2.69B$3.61B
Average payables$14.46B$3.45B$2.91B$2.69B$2.59B$2.06B$1.75B$2.00B$1.98B$2.57B
Average inventory$5.92B$5.36B$5.06B$6.84B$6.50B$3.61B$3.04B$2.96B$2.68B$2.24B
Intangibles / total assets51.8%55.9%57.5%61.3%59.2%49.1%53.0%55.5%60.0%62.8%

Computed from AZN's annual financial statements (latest annual report filed February 24, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

AZN valuation and financial ratios

At the end of fiscal 2025 (December 31, 2025), AstraZeneca traded at 28.0 times earnings, against a 10-year median of 35.3. Based on the latest twelve months, the trailing P/E is 23.8 and the forward P/E is 14.6. AstraZeneca earned a return on equity of 22.9% and a return on invested capital of 16.4% in fiscal 2025. It ended the year with $29.7 billion of debt and $5.7 billion in cash and short-term investments, net debt of $24.0 billion. It returned $5.7 billion to shareholders: $5.0 billion in dividends and $719.7 million in share buybacks, 66% of free cash flow. The share count rose 23.4% from 1.27B to 1.56B over 9 years.

See the AZN income statement, the AZN chart for price history, or the AZN stock overview for the latest quote and news.

AZN key metrics FAQ

What is AstraZeneca's P/E ratio?

AstraZeneca's trailing P/E ratio is 23.8 based on the last twelve months of earnings (as of October 18, 2026), and its forward P/E is 14.6. At the end of fiscal 2025 it was 28.0, compared with a 10-year median of 35.3.

What is AstraZeneca's EV/EBITDA?

AstraZeneca's enterprise value was 15.7 times EBITDA at the end of fiscal 2025 (enterprise value $311.2 billion, EBITDA $19.8 billion); the current EV/EBITDA is 14.2.

What is AstraZeneca's return on equity?

AstraZeneca's return on equity (ROE) was 22.9% in fiscal 2025: net income of $10.3 billion on average shareholders' equity of $44.7 billion.

What is AstraZeneca's ROIC?

AstraZeneca's return on invested capital was 16.4% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does AstraZeneca have?

AstraZeneca had total debt of $29.7 billion at the end of fiscal 2025, a debt-to-equity ratio of 0.61 and $24.0 billion of net debt (1.21 times EBITDA).

What is AstraZeneca's dividend yield?

AstraZeneca's forward dividend yield is 1.93%. AstraZeneca paid $5.0 billion in dividends in fiscal 2025 ($3.18 per share), a payout ratio of 48.5%.

Does AstraZeneca buy back its shares?

Yes. AstraZeneca spent $719.7 million on net share repurchases in fiscal 2025 Shares outstanding changed −0.1% over the year, to 1.56B..

What is AstraZeneca's free cash flow yield?

AstraZeneca generated $8.7 billion of free cash flow in fiscal 2025, a free cash flow yield of 3.0% on its market value at year-end ($287.2 billion).

What is AstraZeneca's current ratio?

AstraZeneca's current ratio was 0.94 at the end of fiscal 2025: current assets were 0.94 times current liabilities.

Drug Manufacturers - General key metrics