Assembly Biosciences, Inc. (ASMB) Key Metrics

NASDAQ: ASMBValuation, returns, debt and efficiency ratios over 10 years.

ASMB valuation today

Trailing 12 months · as of October 17, 2026
Market cap
$409.0M
Enterprise value
$200.2M
P/E (TTM)
19.3
Forward P/E
500.0
PEG ratio
—
Price / sales
5.5
10-yr median 5.3
Price / book
1.7
10-yr median 1.8
EV / EBITDA
0.4
Dividend yield
—
Beta
1.16

ASMB key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

ASMB valuation Price multiples at each fiscal year-end price.

Price / sales+58.7%
5.3
2025 · hover or tap a bar for each year
2023: 6.32024: 3.3 (−47.2%)2025: 5.3 (+58.7%)
20162025
Price / book−35.1%
1.8
2025 · hover or tap a bar for each year
2023: 1.12024: 2.8 (+159.1%)2025: 1.8 (−35.1%)
20162025
Free cash flow yield+43.2 pts
−10.8%
2025 · hover or tap a bar for each year
2023: 49.9%2024: −54.0% (−103.9 pts)2025: −10.8% (+43.2 pts)
20162025

ASMB valuation history

Fiscal year-endToday10-year median

ASMB returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

ASMB debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

ASMB price vs earnings per share

Share price at year-endEPS (right axis)

ASMB key metrics

2016–2025
Assembly Biosciences, Inc. key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$381.3M$94.8M$45.0M———————
Enterprise value$135.8M−$14.2M−$82.9M———————
Price / sales5.33.36.3———————
Price / book1.82.81.1———————
Price / free cash flow——2.0———————
Price / operating cash flow——2.0———————
EV / sales1.9-0.5-11.6———————
Earnings yield−1.6%−42.4%−135.9%———————
Free cash flow yield−10.8%−54.0%49.9%———————
Share price at fiscal year-end$34.01$15.78$9.84$15.60$27.96$72.60$245.52$271.44$543.00$145.80
Per share
Revenue per share$6.45$4.75$1.56———————
Earnings per share−$0.55−$6.69−$13.38———————
Operating cash flow per share−$3.67−$8.51$4.97———————
Free cash flow per share−$3.67−$8.52$4.91———————
Cash per share$22.13$18.67$28.45———————
Book value per share$18.44$5.56$8.98———————
Tangible book value per share$18.44$5.56$8.98———————
Capex per share$0.01$0.00$0.06———————
Debt per share$0.23$0.51$0.51———————
Shares outstanding11.2M6.0M4.6M———————
Change in shares outstanding+86.7%+31.2%————————
Returns & profitability
Return on equity (ROE)−5.1%−107.9%−98.9%−73.2%−63.4%−24.2%−40.4%−56.1%−44.4%−44.6%
Return on invested capital (ROIC)————−332.4%−223.8%———−91.7%
Return on assets (ROA)−3.2%−31.4%−51.3%−62.9%−54.8%−19.7%−31.7%−41.5%−32.0%−38.2%
Return on tangible assets−2.4%−33.7%−44.7%−90.4%−68.0%−25.7%−31.9%−40.1%−33.5%−78.4%
Free cash flow margin−56.9%−179.3%313.9%——−82.4%−536.4%−441.1%11.0%—
Financial health
Total debt$2.6M$3.1M$2.3M$3.5M$6.5M$10.1M$12.3M—$0$0
Cash & short-term investments$248.1M$112.1M$130.2M$91.6M$146.6M$216.4M$274.0M$218.1M$119.9M$53.0M
Net debt−$245.5M−$109.0M−$127.9M−$88.1M−$140.2M−$206.3M−$261.8M−$218.1M−$119.9M−$53.0M
Debt / equity0.010.090.060.040.040.040.04—0.000.00
Debt / assets0.010.030.020.030.030.040.04—0.000.00
Current ratio5.222.423.415.959.599.1911.5712.059.137.52
Quick ratio5.222.423.495.959.599.1911.5712.059.137.52
Interest coverage———-189.0-1.6-24.7-21.4———
Working capital$205.8M$67.7M$94.6M$80.7M$138.1M$200.1M$258.3M$204.0M$109.6M$46.5M
Invested capital−$38.7M−$75.6M−$86.8M−$5.5M$28.8M$34.3M$11.4M−$7.4M−$6.8M$26.9M
Tangible asset value$206.8M$33.4M$41.1M$82.7M$168.9M$198.9M$231.6M$169.0M$71.5M$38.2M
Net current asset value$203.7M$29.7M$38.1M$77.8M$132.1M$181.8M$208.1M$165.1M$66.9M$35.3M
Graham net-net per share$17.66$4.42$7.20———————
Capital allocation
Dividends paid————————$0$0
Share buybacks (net)———$0—$0$0$0$0$0
Dividends + buybacks / free cash flow————————0.0%—
Capex / revenue0.1%0.1%3.6%—49.5%2.8%9.7%2.3%9.6%—
Capex / operating cash flow——1.1%—————46.5%—
Capex / depreciation0.510.220.570.206.643.213.150.533.941.82
Stock-based compensation / revenue6.5%10.9%71.5%—83.7%27.6%128.8%192.4%95.4%—
R&D / revenue89.6%196.1%682.7%—1,095.7%135.0%537.2%491.4%490.4%—
SG&A / revenue27.1%63.1%319.8%—460.2%46.6%206.2%235.1%188.7%—
Efficiency
Days sales outstanding3.52.825.1—45.710.666.458.092.0—
Days of inventory on hand——-11.90.00.0——0.00.0—
Days payables outstanding2,484.33.411.01,888.02,842.111.411.514.618.58,486.6
Cash conversion cycle (days)-2,480.8-0.62.2—-2,796.4-0.854.843.473.5—
Receivables turnover105.24128.7614.510.007.9934.365.506.293.97—
Payables turnover0.15106.9533.110.190.1332.0231.6225.0119.690.04
Inventory turnover———498,000.00932,000.00——72,741,000.0088,450,000.00—
Asset turnover0.380.220.060.000.030.250.050.070.070.00
Average receivables$687,000$221,500$493,500$640,000$783,000$2.3M$2.9M$2.4M$2.3M—
Average payables$878,000$523,000$1.5M$2.6M$3.6M$3.2M$2.7M$2.9M$2.2M$1.9M
Average inventory——−$1.6M$1$0$0$0$1$0$0
Intangibles / total assets0.0%0.0%0.0%0.0%0.0%14.7%12.0%15.5%24.6%42.4%

Computed from ASMB's annual financial statements (latest annual report filed March 19, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

ASMB valuation and financial ratios

Based on the latest twelve months, the trailing P/E is 19.3 and the forward P/E is 500.0. Assembly Biosciences earned a return on equity of −5.1% in fiscal 2025. It ended the year with $2.6 million of debt and $248.1 million in cash and short-term investments, a net cash position of $245.5 million.

See the ASMB income statement, the ASMB chart for price history, or the ASMB stock overview for the latest quote and news.

ASMB key metrics FAQ

What is Assembly Biosciences's P/E ratio?

Assembly Biosciences's trailing P/E ratio is 19.3 based on the last twelve months of earnings (as of October 17, 2026), and its forward P/E is 500.0. At the end of fiscal 2025 it was —.

What is Assembly Biosciences's return on equity?

Assembly Biosciences's return on equity (ROE) was −5.1% in fiscal 2025: net income of -$6.1 million on average shareholders' equity of $120.1 million.

How much debt does Assembly Biosciences have?

Assembly Biosciences had total debt of $2.6 million at the end of fiscal 2025, a debt-to-equity ratio of 0.01 and more cash than debt.

What is Assembly Biosciences's free cash flow yield?

Assembly Biosciences generated -$41.2 million of free cash flow in fiscal 2025, a free cash flow yield of −10.8% on its market value at year-end ($381.3 million).

What is Assembly Biosciences's current ratio?

Assembly Biosciences's current ratio was 5.22 at the end of fiscal 2025: current assets were 5.22 times current liabilities.

Biotechnology key metrics