Septerna, Inc. (SEPN) Stock Forecast
SEPN analyst forecast
as of October 18, 2026- Analyst consensus
- Strong buy 4.90 / 5 from 10 analysts
- Price target
- $54.22 average of analyst targets
- Upside to target
- +49.2% from the latest close
- Next earnings
- November 9, 2026 EPS estimate $-0.55
- 52-week range
- $18.10 – $48.19
SEPN analyst ratings
10 analystsNumber of analysts at each rating.
SEPN price target
The average of analyst 12-month price targets compared with the latest close and the 52-week range.
SEPN earnings per share estimates
| Period | Average | Low | High | Year ago | Growth | Analysts |
|---|---|---|---|---|---|---|
| Current quarter (Sep '26) | −$0.40 | −$0.69 | −$0.24 | −$0.10 | −306.4% | 4 |
| Current fiscal year (2026) | −$1.19 | −$1.36 | −$1.03 | −$1.39 | +14.4% | 4 |
| Next fiscal year (2027) | −$1.94 | −$2.64 | −$1.41 | −$1.19 | −63.5% | 4 |
Consensus EPS estimates; growth compares the average estimate with the year-ago EPS.
SEPN revenue estimates
| Period | Average | Low | High | Growth | Analysts |
|---|---|---|---|---|---|
| Current quarter (Sep '26) | $20.8M | $0 | $32.0M | −3.3% | 10 |
| Current fiscal year (2026) | $96.1M | $53.3M | $118.0M | +109.2% | 10 |
| Next fiscal year (2027) | $73.6M | $0 | $123.0M | −23.4% | 10 |
SEPN EPS: reported and forecast
Fiscal years; "E" marks estimates, the line shows the range from the lowest to the highest estimate.
SEPN revenue: reported and forecast
SEPN EPS estimate revisions
| Period | 90 days ago | 60 days ago | 30 days ago | 7 days ago | Now | Change (90 d) | Revisions (30 d) |
|---|---|---|---|---|---|---|---|
| Current quarter (Sep '26) | −$0.55 | −$0.55 | −$0.41 | −$0.40 | −$0.40 | −28.2% | 2 up · 1 down |
| Current fiscal year (2026) | −$1.84 | −$1.84 | −$1.18 | −$1.19 | −$1.19 | −35.5% | 2 up · 2 down |
| Next fiscal year (2027) | −$2.66 | −$2.66 | −$1.83 | −$1.94 | −$1.94 | −27.0% | 2 up · 2 down |
How the consensus EPS estimate changed over the last 90 days, and how many analysts raised or lowered it in the last 30 days.
SEPN earnings surprises
Reported EPS vs the consensus estimate for the last 9 quarters; SEPN beat in 4 of 9.
What analysts expect from SEPN
10 analysts cover Septerna; their consensus rating is strong buy (4.90 on a 1–5 scale, where 5 is a strong buy). The average price target is $54.22, 49.2% above the latest close of $36.35. Analysts expect earnings of −$1.19 per share for 2026, +14.4% from a year earlier. For 2027 the average estimate is −$1.94 per share on revenue of $73.6 million. Septerna beat the EPS estimate in 4 of the last 9 quarters.
Related: SEPN income statement, SEPN key metrics, SEPN chart. See the SEPN stock overview for the latest quote and news.
SEPN forecast FAQ
What is Septerna's price target?
The average analyst price target for Septerna is $54.22, 49.2% above the latest close of $36.35.
Is Septerna a buy, hold or sell?
Of 10 analysts covering Septerna, 9 rate it a strong buy, 1 a buy, 0 a hold, 0 a sell and 0 a strong sell, a consensus of strong buy. Ratings are opinions, not a recommendation from Quotelinks.
What is Septerna's EPS forecast?
Analysts forecast −$1.19 per share for 2026 (range −$1.36 to −$1.03); for 2027 the estimate is −$1.94.
What is Septerna's revenue forecast?
The average revenue estimate for 2026 is $96.1 million, growth of 109.2%; for 2027 it is $73.6 million.
When does Septerna report earnings?
Septerna is expected to report results for the quarter ending September 30, 2026 on November 9, 2026 after the market closes; the EPS estimate is $-0.55.
Does Septerna usually beat earnings estimates?
Septerna reported EPS at or above the analyst estimate in 4 of the last 9 quarters.