Denali Therapeutics Inc. (DNLI) Stock Forecast

NASDAQ: DNLIAnalyst ratings, price target and estimates.

DNLI analyst forecast

as of October 17, 2026
Analyst consensus
Strong buy
4.80 / 5 from 20 analysts
Price target
$35.75
average of analyst targets
Upside to target
+103.0%
from the latest close
Next earnings
November 5, 2026
EPS estimate $-0.68
52-week range
$14.41 – $27.21

DNLI analyst ratings

20 analysts
Strong buy
1785%
Buy
210%
Hold
15%
Sell
00%
Strong sell
00%

Number of analysts at each rating.

DNLI price target

Price $17.61Target $35.75
52-week low $14.4152-week high $27.21

The average of analyst 12-month price targets compared with the latest close and the 52-week range.

DNLI earnings per share estimates

Denali Therapeutics Inc. EPS estimates
PeriodAverageLowHighYear agoGrowthAnalysts
Current quarter (Sep '26)−$0.37−$0.88$0.38−$0.74+50.4%17
Current fiscal year (2026)−$2.23−$2.75−$0.22−$2.97+25.0%17
Next fiscal year (2027)−$2.42−$3.20−$1.70−$2.23−8.5%17

Consensus EPS estimates; growth compares the average estimate with the year-ago EPS.

DNLI revenue estimates

Denali Therapeutics Inc. revenue estimates
PeriodAverageLowHighGrowthAnalysts
Current quarter (Sep '26)$22.9M$7.5M$204.6M0.0%18
Current fiscal year (2026)$50.7M$21.9M$262.2M0.0%19
Next fiscal year (2027)$130.8M$60.9M$234.5M+158.3%19

DNLI EPS: reported and forecast

Reported EPSEstimate (average; low–high)

Fiscal years; "E" marks estimates, the line shows the range from the lowest to the highest estimate.

DNLI revenue: reported and forecast

Reported revenueEstimate (average; low–high)

DNLI EPS estimate revisions

Denali Therapeutics Inc. EPS estimate revisions
Period90 days ago60 days ago30 days ago7 days agoNowChange (90 d)Revisions (30 d)
Current quarter (Sep '26)−$0.55−$0.41−$0.37−$0.37−$0.37−33.0%2 up · 0 down
Current fiscal year (2026)−$2.35−$2.29−$2.22−$2.22−$2.23−5.3%0 up · 1 down
Next fiscal year (2027)−$2.49−$2.43−$2.42−$2.42−$2.42−2.7%1 up · 2 down

How the consensus EPS estimate changed over the last 90 days, and how many analysts raised or lowered it in the last 30 days.

DNLI earnings surprises

Reported EPSEstimate

Reported EPS vs the consensus estimate for the last 12 quarters; DNLI beat in 9 of 12.

What analysts expect from DNLI

20 analysts cover Denali Therapeutics; their consensus rating is strong buy (4.80 on a 1–5 scale, where 5 is a strong buy). The average price target is $35.75, 103.0% above the latest close of $17.61. Analysts expect earnings of −$2.23 per share for 2026, +25.0% from a year earlier. For 2027 the average estimate is −$2.42 per share on revenue of $130.8 million. Denali Therapeutics beat the EPS estimate in 9 of the last 12 quarters.

Related: DNLI income statement, DNLI key metrics, DNLI chart. See the DNLI stock overview for the latest quote and news.

DNLI forecast FAQ

What is Denali Therapeutics's price target?

The average analyst price target for Denali Therapeutics is $35.75, 103.0% above the latest close of $17.61.

Is Denali Therapeutics a buy, hold or sell?

Of 20 analysts covering Denali Therapeutics, 17 rate it a strong buy, 2 a buy, 1 a hold, 0 a sell and 0 a strong sell, a consensus of strong buy. Ratings are opinions, not a recommendation from Quotelinks.

What is Denali Therapeutics's EPS forecast?

Analysts forecast −$2.23 per share for 2026 (range −$2.75 to −$0.22); for 2027 the estimate is −$2.42.

What is Denali Therapeutics's revenue forecast?

The average revenue estimate for 2026 is $50.7 million, growth of 0.0%; for 2027 it is $130.8 million.

When does Denali Therapeutics report earnings?

Denali Therapeutics is expected to report results for the quarter ending September 30, 2026 on November 5, 2026 after the market closes; the EPS estimate is $-0.68.

Does Denali Therapeutics usually beat earnings estimates?

Denali Therapeutics reported EPS at or above the analyst estimate in 9 of the last 12 quarters.

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