Zenas BioPharma, Inc. (ZBIO) Cash Flow Statement

NASDAQ: ZBIOOperating cash, capex, free cash flow and buybacks.

Where ZBIO’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$172.3M
Capital expenditures
$18,000
0.2% of revenue
Free cash flow
−$172.4M
−1,723.5% margin
Returned to shareholders
—
Change in cash
−$209.2M
cash at year-end $110.6M
Shares issued: $148.6MShares issued$148.6MOther financing: $66.4MOther financing$66.4MDrawn from cash: $209.2MDrawn from cash$209.2MInvestments (net): $216.9MInvestments (net)$216.9M · 51%Cash used in operations: $172.3MCash used in operations$172.3M · 41%Acquisitions & other: $35.0MAcquisitions & other$35.0M · 8%Capital expenditures: $18,000Capital expenditures$18,000 · 0%$424.2M
Cash from operations
−$172.3M
Investments (net)
−$216.9M
Acquisitions & other
−$35.0M
Shares issued
+$148.6M
Other financing
+$66.4M
Change in cash
−$209.2M

Drawn to scale: where the cash came from and how it was used. Hover for values.

ZBIO operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

ZBIO cash flow trends, 2022–2025

Zenas BioPharma, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$65.7M2022−$172.3M2025—
Capital expenditures$2.2M2022$18,0002025−79.8%/yr
Free cash flow−$67.8M2022−$172.4M2025—
Free cash flow margin−61.1%2023−1,723.5%2025−1,662.4 pts
Stock-based compensation$737,0002022$26.3M2025+229.4%/yr
Capex / revenue0.0%20230.2%2025+0.1 pts

Change is the average annual growth (CAGR) or the difference between the first and latest year.

ZBIO cash flow by activity

OperatingInvestingFinancingChange in cash

ZBIO net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

ZBIO cash flow statement

Zenas BioPharma, Inc. annual cash flow statement
2025202420232022
Operating activities
Net income−$377.7M−$157.0M−$37.1M−$119.3M
Depreciation & amortization$56,000$137,000$113,000$78,000
Stock-based compensation$26.3M$10.8M$3.5M$737,000
Change in working capital$951,000$25.4M−$8.0M$8.0M
Other non-cash items$178.1M$925,000$11.0M$44.8M
Cash from operating activities−$172.3M−$119.7M−$30.5M−$65.7M
Investing activities
Capital expenditures−$18,000−$131,000−$17,000−$2.2M
Investments (net)−$216.9M−$30.6M−$17,000−$2.2M
Acquisitions & other investing−$35.0M$131,000$17,000$2.2M
Cash from investing activities−$251.9M−$30.6M−$17,000−$2.2M
Financing activities
Share repurchases & issuance (net)$276,000———
Net borrowing (repayment)—$0$20.0M$0
Shares issued$148.6M$419.0M$0$59.4M
Other financing$66.4M−$6.1M$116,000$0
Cash from financing activities$215.3M$413.0M$20.1M$59.4M
Summary
Net change in cash−$209.2M$262.9M−$10.4M−$8.5M
Cash at end of period$110.6M$319.8M$56.9M$67.3M
Free cash flow−$172.4M−$119.8M−$30.5M−$67.8M
Free cash flow margin−1,723.5%−2,396.1%−61.1%—
Capex / revenue0.2%2.6%0.0%—

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

ZBIO cash generation

In fiscal 2025 (ended December 31, 2025), Zenas BioPharma generated -$172.3 million of cash from operations and spent $0.0 million on capital expenditures, leaving free cash flow of -$172.4 million, −1,723.5% of revenue. Cash and equivalents fell by $209.2 million over the year.

Related: ZBIO income statement, ZBIO balance sheet. See the ZBIO stock overview for the latest quote and news.

ZBIO cash flow FAQ

What is Zenas BioPharma's free cash flow?

Zenas BioPharma's free cash flow was -$172.4 million in fiscal 2025: -$172.3 million of operating cash flow minus $0.0 million of capital expenditures It was -$119.8 million a year earlier..

How much cash does Zenas BioPharma generate from operations?

Zenas BioPharma generated -$172.3 million of cash from operating activities in fiscal 2025.

How much does Zenas BioPharma spend on capital expenditures?

Zenas BioPharma spent $0.0 million on capital expenditures in fiscal 2025, 0.2% of revenue, compared with $0.1 million the year before.

Biotechnology: cash flow