Sionna Therapeutics, Inc. (SION) Cash Flow Statement

NASDAQ: SIONOperating cash, capex, free cash flow and buybacks.

Where SION’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$66.3M
Capital expenditures
$377,000
Free cash flow
−$66.7M
Returned to shareholders
—
Change in cash
$20.7M
cash at year-end $59.4M
Shares issued: $202.1MShares issued$202.1MOther financing: $3.6MOther financing$3.6MInvestments (net): $118.4MInvestments (net)$118.4M · 58%Cash used in operations: $66.3MCash used in operations$66.3M · 32%Added to cash: $20.7MAdded to cash$20.7M · 10%Capital expenditures: $377,000Capital expenditures$377,000 · 0%$205.7M
Cash from operations
−$66.3M
Capital expenditures
−$377,000
Investments (net)
−$118.4M
Shares issued
+$202.1M
Other financing
+$3.6M
Change in cash
$20.7M

Drawn to scale: where the cash came from and how it was used. Hover for values.

SION operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

SION cash flow trends, 2022–2025

Sionna Therapeutics, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$36.1M2022−$66.3M2025—
Capital expenditures$1.9M2022$377,0002025−41.4%/yr
Free cash flow−$37.9M2022−$66.7M2025—
Stock-based compensation$1.7M2022$12.1M2025+92.7%/yr

Change is the average annual growth (CAGR) or the difference between the first and latest year.

SION cash flow by activity

OperatingInvestingFinancingChange in cash

SION net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

SION cash flow statement

Sionna Therapeutics, Inc. annual cash flow statement
2025202420232022
Operating activities
Net income−$75.3M−$61.7M−$47.3M−$40.2M
Depreciation & amortization$647,000$668,000$583,000$122,000
Stock-based compensation$12.1M$3.7M$2.3M$1.7M
Change in working capital−$2.7M−$3.1M−$783,000$2.8M
Other non-cash items−$1.1M$7.6M$1.5M−$400,000
Cash from operating activities−$66.3M−$52.8M−$43.7M−$36.1M
Investing activities
Capital expenditures−$377,000−$27,000−$1.1M−$1.9M
Investments (net)−$118.4M−$126.9M$27.4M−$29.3M
Acquisitions & other investing$0$27,000$1.1M$1.9M
Cash from investing activities−$118.7M−$126.9M$27.4M−$29.3M
Financing activities
Shares issued$202.1M$181.3M$0$110.8M
Other financing$3.6M−$2.4M$31,000$64,000
Cash from financing activities$205.7M$179.0M$31,000$110.9M
Summary
Net change in cash$20.7M−$733,000−$16.3M$45.5M
Cash at end of period$59.4M$38.8M$39.5M$55.8M
Free cash flow−$66.7M−$52.8M−$44.8M−$37.9M

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

SION cash generation

In fiscal 2025 (ended December 31, 2025), Sionna Therapeutics generated -$66.3 million of cash from operations and spent $0.4 million on capital expenditures, leaving free cash flow of -$66.7 million. Cash and equivalents rose by $20.7 million over the year.

Related: SION income statement, SION balance sheet. See the SION stock overview for the latest quote and news.

SION cash flow FAQ

What is Sionna Therapeutics's free cash flow?

Sionna Therapeutics's free cash flow was -$66.7 million in fiscal 2025: -$66.3 million of operating cash flow minus $0.4 million of capital expenditures It was -$52.8 million a year earlier..

How much cash does Sionna Therapeutics generate from operations?

Sionna Therapeutics generated -$66.3 million of cash from operating activities in fiscal 2025.

How much does Sionna Therapeutics spend on capital expenditures?

Sionna Therapeutics spent $0.4 million on capital expenditures in fiscal 2025, compared with $0.0 million the year before.

Biotechnology: cash flow