Odyssey Therapeutics, Inc. (ODTX) Cash Flow Statement

NASDAQ: ODTXOperating cash, capex, free cash flow and buybacks.

Where ODTX’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$129.5M
Capital expenditures
$1.2M
41.4% of revenue
Free cash flow
−$130.7M
−4,391.8% margin
Returned to shareholders
—
Change in cash
−$17.4M
cash at year-end $44.9M
Shares issued: $212.5MShares issued$212.5MDrawn from cash: $17.4MDrawn from cash$17.4MOther financing, Currency & other: $3.9MOther sources$3.9MCash used in operations: $129.5MCash used in operations$129.5M · 55%Investments (net): $103.1MInvestments (net)$103.1M · 44%Capital expenditures: $1.2MCapital expenditures$1.2M · 1%$233.8M
Cash from operations
−$129.5M
Capital expenditures
−$1.2M
Investments (net)
−$103.1M
Shares issued
+$212.5M
Other financing
+$3.2M
Currency & other
+$673,000
Change in cash
−$17.4M

Drawn to scale: where the cash came from and how it was used. Hover for values.

ODTX operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

ODTX cash flow trends, 2022–2025

Odyssey Therapeutics, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$99.8M2022−$129.5M2025—
Capital expenditures$13.0M2022$1.2M2025−54.4%/yr
Free cash flow−$112.9M2022−$130.7M2025—
Free cash flow margin−11,358.1%2023−4,391.8%2025+6,966.3 pts
Stock-based compensation$5.5M2022$14.3M2025+37.4%/yr
Capex / revenue487.6%202341.4%2025−446.2 pts

Change is the average annual growth (CAGR) or the difference between the first and latest year.

ODTX cash flow by activity

OperatingInvestingFinancingChange in cash

ODTX net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

ODTX cash flow statement

Odyssey Therapeutics, Inc. annual cash flow statement
2025202420232022
Operating activities
Net income−$148.6M−$129.3M−$125.9M−$124.7M
Depreciation & amortization$4.9M$5.2M$4.9M$2.8M
Stock-based compensation$14.3M$8.7M$6.3M$5.5M
Change in working capital−$4.7M−$3.3M$896,000−$544,000
Other non-cash items$4.7M$1.3M$1.1M$17.1M
Cash from operating activities−$129.5M−$117.5M−$112.7M−$99.8M
Investing activities
Capital expenditures−$1.2M−$764,000−$5.1M−$13.0M
Investments (net)−$103.1M$97.5M−$160.0M$0
Acquisitions & other investing$357,000———
Cash from investing activities−$103.9M———
Financing activities
Net borrowing (repayment)——−$4.8M$4.9M
Shares issued$212.5M$27.5M$96.6M$177.8M
Other financing$3.2M−$498,000$264,000$76,000
Cash from financing activities$215.6M$27.0M$92.1M$182.7M
Summary
Net change in cash−$17.4M$6.3M−$185.7M$69.8M
Cash at end of period$44.9M$62.3M$56.0M$241.7M
Free cash flow−$130.7M−$118.2M−$117.8M−$112.9M
Free cash flow margin−4,391.8%−2,643.9%−11,358.1%—
Capex / revenue41.4%17.1%487.6%—

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

ODTX cash generation

In fiscal 2025 (ended December 31, 2025), Odyssey Therapeutics generated -$129.5 million of cash from operations and spent $1.2 million on capital expenditures, leaving free cash flow of -$130.7 million, −4,391.8% of revenue. Cash and equivalents fell by $17.4 million over the year.

Related: ODTX income statement, ODTX balance sheet. See the ODTX stock overview for the latest quote and news.

ODTX cash flow FAQ

What is Odyssey Therapeutics's free cash flow?

Odyssey Therapeutics's free cash flow was -$130.7 million in fiscal 2025: -$129.5 million of operating cash flow minus $1.2 million of capital expenditures It was -$118.2 million a year earlier..

How much cash does Odyssey Therapeutics generate from operations?

Odyssey Therapeutics generated -$129.5 million of cash from operating activities in fiscal 2025.

How much does Odyssey Therapeutics spend on capital expenditures?

Odyssey Therapeutics spent $1.2 million on capital expenditures in fiscal 2025, 41.4% of revenue, compared with $0.8 million the year before.

Biotechnology: cash flow