Definium Therapeutics, Inc. (DFTX) Cash Flow Statement

NASDAQ: DFTXOperating cash, capex, free cash flow and buybacks.

Where DFTX’s cash came from and went, 2025

December 31, 2025 · U.S. dollars
Cash from operations
−$131.6M
Capital expenditures
$0
Free cash flow
−$131.6M
Returned to shareholders
—
Change in cash
−$15.9M
cash at year-end $257.8M
Borrowing: $20.0MBorrowing$20.0MShares issued: $258.9MShares issued$258.9MDrawn from cash: $15.9MDrawn from cash$15.9MInvestments (net): $151.6MInvestments (net)$151.6M · 51%Cash used in operations: $131.6MCash used in operations$131.6M · 45%Other financing: $11.6MOther financing$11.6M · 4%$294.8M
Cash from operations
−$131.6M
Investments (net)
−$151.6M
Net borrowing (repayment)
+$20.0M
Shares issued
+$258.9M
Other financing
−$11.6M
Change in cash
−$15.9M

Drawn to scale: where the cash came from and how it was used. Hover for values.

DFTX operating cash flow, capex and free cash flow

Operating cash flowCapital expendituresFree cash flowFCF margin (right axis)

DFTX cash flow trends, 2016–2025

Definium Therapeutics, Inc. cash flow trends
MetricTrendThenLatestChange
Operating cash flow−$26,6362016−$131.6M2025—
Capital expenditures$30,0982016$02025−100.0%
Free cash flow−$56,7342016−$131.6M2025—
Stock-based compensation$7.4M2020$20.1M2025+22.1%/yr

Change is the average annual growth (CAGR) or the difference between the first and latest year.

DFTX cash flow by activity

OperatingInvestingFinancingChange in cash

DFTX net income vs operating cash flow

Net incomeOperating cash flow

Operating cash flow above net income usually means earnings are backed by cash (depreciation and stock-based pay are non-cash expenses).

DFTX cash flow statement

Definium Therapeutics, Inc. annual cash flow statement
2025202420232022202120202019201820172016
Operating activities
Net income−$183.8M−$108.7M−$95.7M−$56.8M−$93.0M−$33.9M−$1.1M−$857,944−$1.2M−$179,900
Depreciation & amortization$0$527,000$3.2M$3.2M$2.6M—$6,684$6,682$5,501—
Stock-based compensation$20.1M$16.9M$15.5M$13.7M$42.7M$7.4M————
Change in working capital$9.4M−$3.3M$6.3M−$3.8M$1.9M$2.1M$207,826−$20,464−$81,759$62,619
Other non-cash items$22.7M$15.5M$6.4M−$6.4M$0$873,000$693,177$149,275$637,007$90,645
Cash from operating activities−$131.6M−$79.1M−$64.4M−$50.1M−$45.8M−$23.6M−$208,119−$722,451−$665,984−$26,636
Investing activities
Capital expenditures$0$0$0$0$0$0−$313,457−$1.0M−$2.1M−$30,098
Investments (net)−$151.6M$0————————
Acquisitions & other investing$0———−$297,000—$100,304$1.6M−$1.5M$62,923
Cash from investing activities−$151.6M———−$297,000—−$213,153$541,335−$3.7M$32,825
Financing activities
Net borrowing (repayment)$20.0M$10.9M$21.7M$0——————
Shares issued$258.9M$250.0M$0$42.3M$81.9M$0$0$0$0$0
Other financing−$11.6M−$7.7M$163,000$16.8M$16.9M$96.7M$288,363$312,051$4.4M−$331
Cash from financing activities$267.3M$253.2M$21.8M$59.1M$98.8M$96.7M$288,363$312,051$4.4M−$331
Summary
Net change in cash−$15.9M$174.0M−$42.4M$8.6M$53.4M$73.4M−$136,860$150,813−$6,984$5,858
Cash at end of period$257.8M$273.7M$99.7M$142.1M$133.5M$80.1M$17,931$154,791$3,978$10,962
Free cash flow−$131.6M−$79.1M−$64.4M−$50.1M−$45.8M−$23.6M−$521,576−$1.8M−$2.8M−$56,734

Negative numbers are cash paid out. Quarterly columns are labeled by the month the quarter ended. Figures in U.S. dollars as reported; data from EODHD.

DFTX cash generation

In fiscal 2025 (ended December 31, 2025), Definium Therapeutics generated -$131.6 million of cash from operations and spent $0 on capital expenditures, leaving free cash flow of -$131.6 million. Cash and equivalents fell by $15.9 million over the year.

Related: DFTX income statement, DFTX balance sheet. See the DFTX stock overview for the latest quote and news.

DFTX cash flow FAQ

What is Definium Therapeutics's free cash flow?

Definium Therapeutics's free cash flow was -$131.6 million in fiscal 2025: -$131.6 million of operating cash flow minus $0 of capital expenditures It was -$79.1 million a year earlier..

How much cash does Definium Therapeutics generate from operations?

Definium Therapeutics generated -$131.6 million of cash from operating activities in fiscal 2025.

Biotechnology: cash flow