Surrozen, Inc. (SRZN) AI Stock Analysis

NASDAQ: SRZNAI research summary: business, growth, valuation, analysts, bull and bear case.

SRZN AI stock analysis summary

AI Research

Surrozen, Inc. (SRZN) is a biotechnology company developing tissue-specific antibodies designed to modulate the Wnt pathway for tissue repair. Over the trailing twelve months, the company generated $11.5M in revenue while posting an operating margin of -207.4% and an EPS of -$39.08. As of June 30, 2026, Surrozen held $102.0M in cash and short-term investments alongside a net cash balance of $95.7M.

Market cap
$275.5M
Revenue (TTM)
$11.5M
P/E
—
1Y return
72.4%
S&P 500 16.8%
Avg. target
$48.40
106.5% vs last close

Bull case

  • Analysts maintain a unanimous outlook with 6 Strong Buy ratings and a mean price target of $48.40, representing 106.5% potential upside from the last close.
  • The balance sheet maintains $102.0M in cash and short-term investments against $6.3M in debt, supporting a net cash balance of $95.7M.
  • Quarterly revenue in the period ended June 30, 2026, increased 408.6% year-over-year, lifting trailing twelve month revenue to $11.5M.

Bear case

  • Annual net losses reached -$242.0M in FY2025, while trailing twelve month operating margin stood at -207.4%.
  • Shareholders' equity was negative at -$218.7M as of June 30, 2026, accompanied by an 891.0% expansion in share count over 5 years.
  • Analyst estimates project revenue to fall 86.0% in the next fiscal year to $1.5M.

What Surrozen does

Surrozen, Inc. is a biotechnology company dedicated to the discovery and advancement of drug candidates that selectively modulate the Wnt pathway to facilitate tissue repair and regeneration. Its approach centers on developing tissue-specific antibodies for conditions affecting organs such as the liver, intestine, retina, cornea, lung, kidney, skin, pancreas, and central nervous system. The pipeline is led by SZN-043, a tissue-specific R-spondin mimetic targeting severe liver diseases, and SZN-1326, a bi-specific antibody designed to modulate Wnt signaling in intestinal crypts. Founded in 2015, the company is based in South San Francisco, California.

Growth and profitability

Surrozen's revenue fell from $12.5M in FY2022 and FY2023 to $10.7M in FY2024 and $3.5M in FY2025, resulting in a 3-year revenue CAGR of -34.7%. Net losses expanded from -$27.7M in FY2022 to -$43.0M in FY2023, -$63.6M in FY2024, and -$242.0M in FY2025, when operating margin reached -1210.6%. For the trailing twelve months ended June 30, 2026, revenue stood at $11.5M with an operating margin of -207.4%. In the latest quarter ended June 30, 2026, quarterly revenue increased 408.6% year-over-year, while quarterly earnings declined 37.0%.

SRZN income statement →

Balance sheet and cash flow

As of June 30, 2026, Surrozen held $102.0M in cash and short-term investments against $6.3M in total debt, creating a net cash position of $95.7M. The company reported total assets of $115.6M, a current ratio of 12.14, and negative shareholders' equity of -$218.7M. In FY2025, operating cash flow was -$30.2M and free cash flow was -$30.4M. Capital expenditures reached $128,000 in FY2025, while share issuances raised $198,000, following an 891.0% increase in share count over 5 years.

SRZN balance sheet →

Valuation and performance

Surrozen trades at a price-to-sales ratio of 23.9x, compared to the median of 4.1x for its US-listed Healthcare peers. Its enterprise value-to-EBITDA stands at 0.7x, below the peer group median of 12.0x, based on an enterprise value of $94.2M and a market capitalization of $275.5M. The stock closed at $23.44 on October 16, 2026, trading 5.3% below its 200-day average. Over the past year, the stock returned 72.4%, outperforming the S&P 500 return of 16.8%, though its 5-year return of -75.3% lagged the index return of 83.0%.

SRZN key metrics →

What analysts expect

Surrozen has 6 Strong Buy ratings from analysts, with 0 Buy, Hold, Sell, or Strong Sell ratings. The mean price target is $48.40, representing an upside of 106.5% from the last close of $23.44. For the fiscal year ending December 31, 2026, consensus estimates project an EPS of -$9.14 on revenue of $10.7M. For the next fiscal year, 3 analysts project revenue to fall to $1.5M alongside an EPS of -$4.19. Surrozen beat EPS estimates in 1 of the last 4 quarters, and its next earnings date is November 6, 2026.

SRZN forecast and price target →

Key risks and what to watch

  • Short interest represents 33.6% of the float, indicating elevated negative sentiment.
  • The company burned -$30.4M in free cash flow in FY2025 while allocating $29.4M to research and development expenses.
  • The stock has experienced steep long-term depreciation, evidenced by a 5-year return of -75.3%.

AI-generated research summary. Written with AI from Quotelinks data as of October 16, 2026 and checked so every figure matches that data. For information only, not investment advice. Disclaimer

About this SRZN AI stock analysis

This page is an AI-written research summary of Surrozen, Inc. (SRZN). The text was generated on October 30, 2026 from Quotelinks data as of October 16, 2026 (company profile, annual results, latest balance sheet, valuation, price performance and analyst estimates). An automatic check rejects any draft that contains a figure not found in that data. It is not investment advice; verify figures on the linked tabs before making decisions.

Related: SRZN income statement, SRZN balance sheet, SRZN key metrics, SRZN analyst forecast, SRZN chart. See the SRZN stock overview for the latest quote and news.

SRZN AI stock analysis FAQ

What drug candidates are in Surrozen's development pipeline?

Surrozen's lead candidates include SZN-043, an R-spondin mimetic being developed for severe liver diseases, and SZN-1326, a bi-specific antibody designed to modulate Wnt signaling in intestinal crypts.

What is Surrozen's cash position?

As of June 30, 2026, Surrozen reported $102.0M in cash and short-term investments and $6.3M in total debt, resulting in net cash of $95.7M.

What are analysts forecasting for Surrozen's earnings and revenue?

For the fiscal year ending December 31, 2026, analysts estimate an EPS of -$9.14 on revenue of $10.7M. For the following fiscal year, 3 analysts project an EPS of -$4.19 and revenue of $1.5M.

Does Surrozen pay a dividend?

Surrozen does not pay a dividend. The company directs its resources toward research and development, which totaled $29.4M in FY2025.

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