Precigen, Inc. (PGEN) AI Stock Analysis
PGEN AI stock analysis summary
AI ResearchPrecigen, Inc. (PGEN) is a clinical-stage biotechnology company focused on gene and cellular therapies. While revenue rose 146.7% in FY2025 to $9.7M and reached $85.7M over the trailing twelve months, net income remained negative at -$250.6M in FY2025 with an EPS of -$1.04 over the trailing twelve months. The stock closed at $6.39 with a 1-year return of 83.1%.
- Market cap
- $2.28B
- Revenue (TTM)
- $85.7M
- P/E
- — fwd 16.9x
- 1Y return
- 83.1% S&P 500 16.8%
- Avg. target
- $13.65 113.6% vs last close
Bull case
- Quarterly revenue grew 6322.7% year-over-year in the quarter ended June 30, 2026.
- Analysts estimate FY2026 revenue of $238.8M and positive EPS of $0.22.
- The analyst mean price target of $13.65 reflects a 113.6% premium over the last close of $6.39.
Bear case
- Free cash flow was -$89.8M and operating cash flow was -$87.8M in FY2025.
- Net income remained deeply negative at -$250.6M in FY2025, representing a net margin of -2588.2%.
- Total debt of $98.3M exceeds cash and short-term investments of $38.2M, leaving net debt at $60.1M as of June 30, 2026.
What Precigen does
Precigen, Inc., based in Germantown, Maryland, is a biotechnology company advancing gene and cellular therapies. Founded in 1998 and previously known as Intrexon Corporation until January 2020, the company develops disease-modifying therapeutics and specialized biological tools. Its portfolio includes genetically engineered swine for regenerative medicine, reproductive technologies, and the UltraVector platform for genetic assembly. Precigen has also developed mbIL15 for immune cell enhancement, the Sleeping Beauty non-viral transposon/transposase system, AdenoVerse engineered adenovector libraries, and L. lactis bacteria. In addition, its technology suite features the RheoSwitch inducible gene switch, UltraCAR-T for cancer therapies, and AdenoVerse Immunotherapy platforms.
Growth and profitability
Precigen reported FY2025 revenue of $9.7M, an increase of 146.7% from $3.9M in FY2024, following a 5-year revenue CAGR of -21.3% from FY2020 to FY2025. Gross margin was 37.1% in FY2025, recovering from -8.7% in FY2024. However, operating margin stood at -1100.8% and net loss expanded to -$250.6M, resulting in an EPS of -$1.39. In the trailing twelve months ended June 30, 2026, revenue totaled $85.7M, supported by quarterly revenue growth of 6322.7% year-over-year. TTM operating margin improved to 41.2%, though profit margin remained negative at -184.0% with an EPS of -$1.04.
Balance sheet and cash flow
As of June 30, 2026, Precigen held $38.2M in cash and short-term investments against total debt of $98.3M, resulting in net debt of $60.1M. Shareholders' equity was $43.6M, yielding a debt-to-equity ratio of 2.26, while the current ratio stood at 4.58. Operating cash flow was -$87.8M in FY2025, and free cash flow was -$89.8M. Cash usage in FY2025 included $2.0M in capital expenditures and $2.2M in share buybacks, while the share count increased 107.6% over the past 5 years.
Valuation and performance
Precigen carries a market capitalization of $2.28B and an enterprise value of $2.72B. The stock trades at a forward P/E of 16.9x, slightly below the 17.3x median of its US-listed Healthcare peers. Its price-to-sales multiple is 26.7x and EV-to-revenue is 31.7x, compared to the peer median price-to-sales of 4.1x. Over the past year, Precigen achieved a return of 83.1%, outperforming the S&P 500 (SPY) return of 16.8%, while its 5-year return of 37.4% trailed the S&P 500 return of 83.0%.
What analysts expect
Wall Street coverage includes 2 Strong Buy, 1 Buy, and 1 Hold ratings, with zero Sell or Strong Sell recommendations. The mean price target of $13.65 indicates an upside of 113.6% over the last close of $6.39. For the fiscal year ending December 31, 2026, consensus estimates project revenue of $238.8M and an EPS of $0.22. Precigen has beaten EPS estimates in 3 of the last 4 quarters, and its next earnings date is scheduled for November 12, 2026.
Key risks and what to watch
- Ongoing cash burn is underscored by FY2025 free cash flow of -$89.8M against $38.2M in cash as of June 30, 2026.
- Shareholder dilution has been substantial, with share count increasing 107.6% over 5 years.
- High market skepticism is evident with short interest at 24.4% of float.
- Valuation multiples are elevated, including a price-to-sales ratio of 26.7x versus the peer median of 4.1x.
AI-generated research summary. Written with AI from Quotelinks data as of October 16, 2026 and checked so every figure matches that data. For information only, not investment advice. Disclaimer
About this PGEN AI stock analysis
This page is an AI-written research summary of Precigen, Inc. (PGEN). The text was generated on October 30, 2026 from Quotelinks data as of October 16, 2026 (company profile, annual results, latest balance sheet, valuation, price performance and analyst estimates). An automatic check rejects any draft that contains a figure not found in that data. It is not investment advice; verify figures on the linked tabs before making decisions.
Related: PGEN income statement, PGEN balance sheet, PGEN key metrics, PGEN analyst forecast, PGEN chart. See the PGEN stock overview for the latest quote and news.
PGEN AI stock analysis FAQ
Does Precigen pay a dividend?
No, Precigen does not pay a dividend. The company allocates cash toward development, reporting free cash flow of -$89.8M in FY2025.
What is Precigen's current cash and debt position?
As of June 30, 2026, Precigen had $38.2M in cash and short-term investments alongside $98.3M in total debt, creating net debt of $60.1M. Its current ratio was 4.58.
What are analysts expecting for Precigen's FY2026 earnings?
Analysts project full-year FY2026 revenue of $238.8M and an EPS of $0.22, which reflects an expected EPS growth of 116.3%.
When is Precigen's next earnings report?
Precigen is scheduled to release its next financial results on November 12, 2026.