Natera, Inc. (NTRA) AI Stock Analysis
NTRA AI stock analysis summary
AI ResearchNatera, Inc. (NASDAQ: NTRA) is a diagnostics company specializing in molecular testing across oncology, prenatal care, and organ health. The company grew revenue at a 5-year CAGR of 42.6% through FY2025 and generated positive free cash flow of $109.1M in FY2025. While trailing twelve month net margin remains negative at -7.1%, its balance sheet holds $853.0M in net cash as of June 30, 2026.
- Market cap
- $56.71B
- Revenue (TTM)
- $2.71B
- P/E
- —
- 1Y return
- 117.9% S&P 500 16.8%
- Avg. target
- $403.89 2.7% vs last close
Bull case
- Revenue increased at a 5-year CAGR of 42.6% from FY2020 through FY2025, supported by 37.7% quarterly revenue growth in the quarter ended June 30, 2026.
- Free cash flow turned positive in FY2024 at $69.2M and expanded to $109.1M in FY2025.
- The balance sheet maintains liquidity with $1.09B in cash and short-term investments, resulting in $853.0M of net cash as of June 30, 2026.
Bear case
- The company remains unprofitable on a GAAP basis, posting a net loss of -$208.2M in FY2025 and trailing twelve months EPS of -$1.35.
- Valuation is elevated relative to the sector, with a price-to-sales ratio of 20.9x compared to the median of 4.1x for US-listed Healthcare peers.
- Shareholders experienced substantial dilution, with the share count expanding 54.8% over the past 5 years.
What Natera does
Natera, Inc. is a diagnostics company providing molecular testing services across multiple stages of health. Its flagship products include Panorama, a non-invasive prenatal test, along with Vistara, Horizon carrier screening, and Spectrum for IVF cycles. It also offers Anora miscarriage tests and non-invasive paternity screening. In oncology, Natera provides Signatera, a circulating tumor DNA technology for cancer mutation monitoring, as well as Prospera for organ transplant rejection assessment. The company also offers Constellation, a cloud-based bioinformatics software for laboratories. Natera distributes products directly and through approximately 100 global laboratory and distribution partners, supported by partnerships with organizations such as BGI Genomics and Foundation Medicine.
Growth and profitability
Annual revenue expanded from $625.5M in FY2021 to $2.31B in FY2025, representing a 5-year revenue CAGR of 42.6%. Gross margin expanded from 49.1% in FY2021 to 64.8% in FY2025, while operating margin improved from -74.8% to -13.4%. Net income was -$208.2M in FY2025 compared to -$471.7M in FY2021. For the trailing twelve months ended June 30, 2026, revenue stood at $2.71B with a net margin of -7.1% and diluted EPS of -$1.35. In the latest quarter ended June 30, 2026, quarterly revenue grew 37.7% year-over-year.
Balance sheet and cash flow
As of June 30, 2026, Natera held $1.09B in cash and short-term investments against $238.5M in total debt, yielding net cash of $853.0M. The company had a current ratio of 3.00 and a debt-to-equity ratio of 0.13. Operating cash flow improved to $215.3M in FY2025, while free cash flow reached $109.1M after capital expenditures of $106.2M. Dilution occurred over recent years, with its 5-year share count increasing by 54.8%.
Valuation and performance
At $393.44 per share on October 16, 2026, Natera carried a market capitalization of $56.71B and an enterprise value of $55.48B. The stock traded at a price-to-sales multiple of 20.9x and an EV-to-revenue multiple of 20.5x, well above the 4.1x price-to-sales median of its US-listed Healthcare peers. Natera's price-to-book ratio stood at 30.9x. Over the 1-year period, NTRA gained 117.9%, outperforming the S&P 500 (SPY) return of 16.8%, and delivered a 5-year return of 255.2% versus 83.0% for the index.
What analysts expect
Wall Street coverage includes 16 Strong Buy, 5 Buy, and 2 Hold ratings, with no Sell or Strong Sell ratings. The mean price target of $403.89 sits 2.7% above the October 16, 2026 closing price of $393.44. For the fiscal year ending December 31, 2026, consensus estimates project revenue of $2.91B and EPS of -$1.47. For the following fiscal year, 15 analysts project revenue of $3.52B, reflecting 20.8% growth, and EPS of -$0.23. The company beat EPS estimates in 1 of the last 4 quarters and is scheduled to report earnings on November 5, 2026.
Key risks and what to watch
- Profitability has yet to be reached, with operating margin at -10.3% and return on equity at -12.5% over the trailing twelve months.
- High valuation multiples, including a price-to-book ratio of 30.9x and EV-to-revenue of 20.5x, leave little room for operational missteps.
- Earnings reliability has been mixed, with the company beating consensus EPS estimates in only 1 of the last 4 quarters.
- The stock has displayed above-average volatility, characterized by a beta of 1.50 and trading 52.8% above its 200-day moving average.
AI-generated research summary. Written with AI from Quotelinks data as of October 16, 2026 and checked so every figure matches that data. For information only, not investment advice. Disclaimer
About this NTRA AI stock analysis
This page is an AI-written research summary of Natera, Inc. (NTRA). The text was generated on October 30, 2026 from Quotelinks data as of October 16, 2026 (company profile, annual results, latest balance sheet, valuation, price performance and analyst estimates). An automatic check rejects any draft that contains a figure not found in that data. It is not investment advice; verify figures on the linked tabs before making decisions.
Related: NTRA income statement, NTRA balance sheet, NTRA key metrics, NTRA analyst forecast, NTRA chart. See the NTRA stock overview for the latest quote and news.
NTRA AI stock analysis FAQ
Does Natera pay a dividend?
No, Natera does not pay a dividend. The company reinvests its cash into operations, such as $624.1M in research and development expenses in FY2025.
What was Natera's revenue growth in FY2025?
Natera generated $2.31B in revenue during FY2025, which represented a 35.9% increase from $1.70B in FY2024.
What is Natera's net debt position?
As of June 30, 2026, Natera had a net cash position of $853.0M, supported by $1.09B in cash and short-term investments against $238.5M in total debt.
What are analysts forecasting for Natera's earnings?
Analysts estimate EPS of -$1.47 on revenue of $2.91B for FY2026, improving to an estimated EPS of -$0.23 on revenue of $3.52B for FY2027.