Natera, Inc. (NTRA) Key Metrics

NASDAQ: NTRAValuation, returns, debt and efficiency ratios over 10 years.

NTRA valuation today

Trailing 12 months · as of October 17, 2026
Market cap
$56.71B
Enterprise value
$55.48B
P/E (TTM)
—
Forward P/E
—
PEG ratio
—
Price / sales
20.9
10-yr median 7.2
Price / book
30.9
10-yr median 14.7
EV / EBITDA
—
Dividend yield
—
Beta
1.50

NTRA key metrics, 2016–2025

Fiscal year ended December 31, 2025 · U.S. dollars

NTRA valuation Price multiples at each fiscal year-end price.

Price / sales+16.7%
13.6
2025 · hover or tap a bar for each year
2016: 2.8 (+2.8%)2017: 2.3 (−17.9%)2018: 3.1 (+37.2%)2019: 7.8 (+147.3%)2020: 20.6 (+166.0%)2021: 13.5 (−34.4%)2022: 4.8 (−64.4%)2023: 6.7 (+38.1%)2024: 11.6 (+74.9%)2025: 13.6 (+16.7%)
20162025
Price / book+10.7%
18.3
2025 · hover or tap a bar for each year
2016: 5.7 (+103.5%)2017: 19.0 (+234.3%)2018: 25.1 (+32.4%)2019: 8.4 (−66.5%)2020: 16.6 (+97.2%)2021: 12.9 (−21.9%)2022: 5.6 (−56.7%)2023: 9.4 (+68.0%)2024: 16.5 (+75.5%)2025: 18.3 (+10.7%)
20162025
Price / free cash flow+0.7%
287.1
2025 · hover or tap a bar for each year
2024: 285.12025: 287.1 (+0.7%)
20162025
Free cash flow yield0.0 pts
0.3%
2025 · hover or tap a bar for each year
2016: −16.1% (−7.2 pts)2017: −22.1% (−6.1 pts)2018: −9.2% (+12.9 pts)2019: −2.9% (+6.3 pts)2020: −2.5% (+0.4 pts)2021: −4.4% (−1.9 pts)2022: −12.1% (−7.7 pts)2023: −4.0% (+8.1 pts)2024: 0.4% (+4.3 pts)2025: 0.3% (0.0 pts)
20162025

NTRA valuation history

Fiscal year-endToday10-year median

NTRA returns on capital

ROEROICROA

Net income (ROE, ROA) or after-tax operating income (ROIC) divided by the average of the opening and closing balance.

NTRA debt vs cash

Total debtCash & short-term investments

Debt includes short- and long-term borrowings and, where reported, lease liabilities.

NTRA cash returned to shareholders

DividendsBuybacksFree cash flow

NTRA price vs earnings per share

Share price at year-endEPS (right axis)

NTRA key metrics

2016–2025
Natera, Inc. key metrics by fiscal year
2025202420232022202120202019201820172016
Valuation
Market capitalization$31.32B$19.74B$7.20B$3.95B$8.46B$8.06B$2.34B$807.6M$481.9M$604.0M
Enterprise value$30.46B$18.96B$6.77B$3.50B$7.94B$7.61B$2.06B$777.2M$486.2M$507.5M
Price / sales13.611.66.74.813.520.67.83.12.32.8
Price / book18.316.59.45.612.916.68.425.119.05.7
Price / free cash flow287.1285.1————————
Price / operating cash flow145.5145.5————————
EV / sales13.211.26.34.312.719.56.83.02.32.3
EV / free cash flow279.2273.9————————
Earnings yield−0.7%−1.0%−6.0%−13.9%−5.6%−2.8%−5.3%−15.9%−28.3%−15.9%
Free cash flow yield0.3%0.4%−4.0%−12.1%−4.4%−2.5%−2.9%−9.2%−22.1%−16.1%
Dividend yield———0.8%—0.1%——0.0%0.4%
Shareholder yield (dividends + buybacks)—0.0%0.0%0.8%0.0%0.1%0.0%0.0%0.0%0.4%
Share price at fiscal year-end$229.09$158.30$62.64$40.17$93.39$99.52$33.69$13.96$8.99$11.71
Per share
Revenue per share$16.87$13.61$9.41$8.33$6.91$4.83$4.35$4.45$3.94$4.21
Earnings per share−$1.52−$1.53−$3.78−$5.57−$5.21−$2.84−$1.79−$2.22−$2.54−$1.86
Operating cash flow per share$1.57$1.09−$2.15−$4.38−$3.70−$2.25−$0.91−$1.22−$1.82−$1.44
Free cash flow per share$0.80$0.56−$2.49−$4.87−$4.15−$2.49−$0.98−$1.29−$1.99−$1.88
Cash per share$7.87$7.76$7.64$9.13$10.10$9.10$6.34$2.66$2.22$2.83
Book value per share$12.52$9.58$6.66$7.17$7.21$6.00$4.01$0.56$0.47$2.06
Tangible book value per share$8.76$9.50$6.66$7.17$7.19$5.98$3.99$0.53$0.43$2.04
Dividends per share———$0.30—$0.09——$0.00$0.05
Capex per share$0.78$0.53$0.34$0.48$0.45$0.24$0.07$0.07$0.18$0.45
Debt per share$1.57$1.50$3.84$4.53$4.39$3.47$2.24$2.14$2.30$0.96
Shares outstanding136.7M124.7M115.0M98.4M90.6M81.0M69.6M57.8M53.6M51.6M
Change in shares outstanding+9.6%+8.5%+16.9%+8.7%+11.8%+16.5%+20.2%+7.9%+3.9%+8.1%
Returns & profitability
Return on equity (ROE)−14.3%−19.4%−59.1%−80.6%−82.8%−60.1%−80.3%−445.1%−206.7%−65.8%
Return on invested capital (ROIC)−38.7%−47.3%−121.2%−219.3%−444.8%——−574.4%−533.3%—
Return on assets (ROA)−10.0%−12.3%−30.7%−41.6%−43.5%−30.3%−29.3%−53.1%−64.1%−40.2%
Return on tangible assets−10.4%−11.5%−30.2%−39.3%−38.2%−24.7%−21.5%−48.1%−64.3%−45.7%
Free cash flow margin4.7%4.1%−26.4%−58.4%−60.2%−51.7%−22.6%−28.9%−50.6%−44.7%
Financial health
Total debt$214.4M$187.1M$442.0M$446.2M$397.2M$281.1M$155.8M$123.5M$123.2M$49.6M
Cash & short-term investments$1.08B$968.3M$879.0M$898.4M$914.3M$737.3M$441.0M$153.9M$118.9M$146.1M
Net debt−$861.8M−$781.2M−$437.0M−$452.2M−$517.0M−$456.2M−$285.2M−$30.4M$4.3M−$96.5M
Debt / equity0.130.160.580.630.610.580.563.844.850.47
Debt / assets0.090.110.310.320.320.300.270.460.570.24
Current ratio3.394.004.103.904.994.332.912.111.711.81
Quick ratio3.243.873.963.794.874.232.841.991.631.74
Interest coverage-76.2-20.8-35.3-58.1-56.4-14.3-10.9-10.9-31.8-181.0
Working capital$1.06B$1.03B$951.3M$901.3M$874.2M$663.6M$343.3M$126.5M$75.1M$77.7M
Invested capital$850.6M$414.3M$328.3M$253.6M$136.3M$30.1M−$6.5M$1.8M$29.7M$10.0M
Tangible asset value$1.20B$1.18B$765.3M$705.7M$651.0M$484.5M$277.5M$30.5M$22.8M$105.2M
Net current asset value$701.3M$910.5M$582.2M$523.1M$510.0M$416.7M$219.2M$4.5M−$8.6M$69.9M
Graham net-net per share$3.93$6.10$3.75$4.17$4.82$4.45$2.63−$0.50−$0.61$1.07
Capital allocation
Dividends paid———$30.0M—$7.1M——$0$2.6M
Share buybacks (net)—$0$0$0$0$0$0$0$0$0
Dividends + buybacks / free cash flow—0.0%————————
Capex / revenue4.6%3.9%3.6%5.8%6.6%5.0%1.6%1.5%4.7%10.7%
Capex / operating cash flow49.3%49.0%————————
Capex / depreciation2.442.141.632.863.652.280.640.521.383.75
Stock-based compensation / revenue15.4%16.2%17.7%18.6%18.4%12.8%9.5%5.5%5.4%4.9%
R&D / revenue27.1%23.8%29.6%38.6%42.2%25.6%17.0%19.9%23.7%19.3%
SG&A / revenue51.0%49.6%57.1%71.8%81.7%77.7%68.2%60.1%73.6%62.9%
Efficiency
Days sales outstanding48.363.788.181.558.561.669.875.349.716.2
Days of inventory on hand25.523.223.624.926.929.127.124.920.119.5
Days payables outstanding15.313.514.323.320.215.024.125.426.225.3
Cash conversion cycle (days)58.573.497.483.165.275.772.774.843.710.4
Receivables turnover7.555.734.144.486.235.935.234.857.3422.54
Payables turnover23.8126.9925.5615.6418.0424.3915.1314.3713.9514.41
Inventory turnover14.3215.7615.4914.6413.5712.5613.4814.6818.1218.69
Asset turnover1.111.090.760.620.580.520.711.070.990.91
Average receivables$305.3M$296.2M$261.3M$183.2M$100.3M$66.0M$57.8M$53.2M$28.7M$9.6M
Average payables$34.0M$25.0M$23.1M$29.2M$17.7M$8.3M$11.6M$11.6M$10.0M$9.4M
Average inventory$56.6M$42.8M$38.1M$31.2M$23.5M$16.2M$13.0M$11.3M$7.7M$7.3M
Intangibles / total assets20.5%0.7%0.0%0.0%0.2%0.2%0.2%0.6%1.2%0.6%

Computed from NTRA's annual financial statements (latest annual report filed February 27, 2026) and the closing share price on each fiscal year-end, adjusted for stock splits. Figures in U.S. dollars; data from EODHD. Averages use the opening and closing balance of each year.

NTRA valuation and financial ratios

Natera earned a return on equity of −14.3% and a return on invested capital of −38.7% in fiscal 2025. It ended the year with $214.4 million of debt and $1.1 billion in cash and short-term investments, a net cash position of $861.8 million. The share count rose 165.1% from 51.6M to 136.7M over 9 years.

See the NTRA income statement, the NTRA chart for price history, or the NTRA stock overview for the latest quote and news.

NTRA key metrics FAQ

What is Natera's return on equity?

Natera's return on equity (ROE) was −14.3% in fiscal 2025: net income of -$208.2 million on average shareholders' equity of $1.5 billion.

What is Natera's ROIC?

Natera's return on invested capital was −38.7% in fiscal 2025, using after-tax operating income divided by average debt plus equity minus cash.

How much debt does Natera have?

Natera had total debt of $214.4 million at the end of fiscal 2025, a debt-to-equity ratio of 0.13 and more cash than debt.

What is Natera's free cash flow yield?

Natera generated $109.1 million of free cash flow in fiscal 2025, a free cash flow yield of 0.3% on its market value at year-end ($31.3 billion).

What is Natera's current ratio?

Natera's current ratio was 3.39 at the end of fiscal 2025: current assets were 3.39 times current liabilities.

Diagnostics & Research key metrics