Mirum Pharmaceuticals, Inc. (MIRM) AI Stock Analysis
MIRM AI stock analysis summary
AI ResearchMirum Pharmaceuticals, Inc. (MIRM) is a commercial-stage biopharmaceutical company focused on developing therapies for rare liver diseases. Annual revenue grew from $19.1M in FY2021 to $521.3M in FY2025, accompanied by positive free cash flow of $54.9M in FY2025. However, the company faces balance sheet challenges with -$10.4M in shareholders' equity and a trailing twelve months net loss of -$14.10 per share.
- Market cap
- $5.20B
- Revenue (TTM)
- $618.1M
- P/E
- — fwd 166.7x
- 1Y return
- 7.7% S&P 500 16.8%
- Avg. target
- $153.07 91.0% vs last close
Bull case
- Annual revenue expanded at a 116.3% 5-year CAGR from FY2020 through FY2025, reaching $521.3M.
- Free cash flow turned positive at $54.9M in FY2025, up from -$151.8M in FY2021.
- The analyst mean price target of $153.07 implies an upside of 91.0% from the last close of $80.14.
Bear case
- Mirum carried negative shareholders' equity of -$10.4M and total debt of $760.5M as of June 30, 2026.
- The stock trades at a forward P/E of 166.7x, well above the US-listed Healthcare peer median of 17.3x.
- Analysts project current fiscal year EPS to plunge to -$15.14, an estimated decline of -3121.3%.
What Mirum Pharmaceuticals does
Mirum Pharmaceuticals, Inc. is a biopharmaceutical company specializing in the development and commercialization of innovative therapies tailored for rare and orphan diseases that significantly impact patients' lives. Its lead product candidate is LIVMARLI, an investigational oral drug addressing critical unmet medical needs in progressive familial intrahepatic cholestasis disease, Alagille syndrome, and biliary atresia disease. The company is also advancing Volixibat for the treatment of intrahepatic cholestasis of pregnancy and primary sclerosing cholangitis. Founded in 2018 and headquartered in Foster City, California, Mirum employs 433 people dedicated to expanding treatment options for liver-related disorders.
Growth and profitability
Mirum achieved a 5-year revenue CAGR of 116.3% from FY2020 through FY2025, with revenue climbing from $19.1M in FY2021 to $77.1M in FY2022, $186.4M in FY2023, $336.9M in FY2024, and $521.3M in FY2025. Gross margin stood at 80.7% in FY2025, while operating margin improved from -906.1% in FY2021 to -4.2% in FY2025. Annual net losses decreased from -$84.0M in FY2021 to -$23.4M in FY2025. For the trailing twelve months ended June 30, 2026, revenue totaled $618.1M with quarterly revenue growth of 37.9%, though trailing profit margin was -139.2% and EPS was -$14.10.
Balance sheet and cash flow
As of June 30, 2026, Mirum held $438.3M in cash and short-term investments alongside $760.5M in total debt, resulting in net debt of $322.3M. Total assets stood at $1.04B, liquidity remained supported by a current ratio of 2.86, and shareholders' equity was -$10.4M. In FY2025, operating cash flow reached $55.8M and free cash flow was $54.9M, while capital expenditures were $954,000. Additionally, the company's share count increased by 107.2% over a 5-year period.
Valuation and performance
Mirum holds a market capitalization of $5.20B and an enterprise value of $6.13B. The stock trades at a forward P/E of 166.7x, compared to the 17.3x median of its US-listed Healthcare peers. Its price-to-sales multiple of 8.4x and EV/EBITDA of 341.2x also trade above peer group medians of 4.1x and 12.0x, respectively. Over the past year, Mirum gained 7.7%, trailing the 16.8% return of the S&P 500, but its 5-year gain of 368.1% outperformed the index return of 83.0%.
What analysts expect
Mirum holds 10 Strong Buy ratings, 4 Buy ratings, and 0 Hold or Sell ratings. The mean price target is $153.07, representing a 91.0% premium over the closing price of $80.14. For the fiscal year ending December 31, 2026, analysts estimate revenue of $696.6M and an EPS of -$15.14. For the following fiscal year, consensus estimates point to revenue of $820.0M and EPS of -$0.72. The company exceeded EPS estimates in 1 of the last 4 quarters, with its next earnings release scheduled for November 3, 2026.
Key risks and what to watch
- Net debt totaled $322.3M as of June 30, 2026, posing obligations against $438.3M in cash reserves.
- Shareholder dilution has been elevated, with the 5-year share count rising 107.2%.
- Earnings execution has been inconsistent, with Mirum beating EPS estimates in only 1 of the last 4 quarters.
- The stock closed 18.7% below its 200-day moving average and short interest is 13.9% of float.
AI-generated research summary. Written with AI from Quotelinks data as of October 16, 2026 and checked so every figure matches that data. For information only, not investment advice. Disclaimer
About this MIRM AI stock analysis
This page is an AI-written research summary of Mirum Pharmaceuticals, Inc. (MIRM). The text was generated on October 30, 2026 from Quotelinks data as of October 16, 2026 (company profile, annual results, latest balance sheet, valuation, price performance and analyst estimates). An automatic check rejects any draft that contains a figure not found in that data. It is not investment advice; verify figures on the linked tabs before making decisions.
Related: MIRM income statement, MIRM balance sheet, MIRM key metrics, MIRM analyst forecast, MIRM chart. See the MIRM stock overview for the latest quote and news.
MIRM AI stock analysis FAQ
What products does Mirum Pharmaceuticals develop?
Mirum develops treatments for rare and orphan diseases, led by LIVMARLI for progressive familial intrahepatic cholestasis, Alagille syndrome, and biliary atresia, as well as Volixibat for liver-related indications.
Does Mirum Pharmaceuticals pay a dividend?
Mirum Pharmaceuticals does not pay a dividend on its common stock.
What is Mirum's current financial and debt position?
As of June 30, 2026, Mirum had $438.3M in cash and short-term investments, $760.5M in debt, a current ratio of 2.86, and shareholders' equity of -$10.4M.
What are analysts forecasting for MIRM stock?
Wall Street analysts hold 10 Strong Buy and 4 Buy ratings with an average price target of $153.07, projecting revenue of $696.6M in FY2026 and $820.0M in FY2027.