BillionToOne, Inc. (BLLN) AI Stock Analysis

NASDAQ: BLLNAI research summary: business, growth, valuation, analysts, bull and bear case.

BLLN AI stock analysis summary

AI Research

BillionToOne, Inc. is a precision diagnostics company that went public in 2025 and specializes in single-count molecular counting platforms. The business achieved profitability in FY2025 with net income of $7.5M on revenue of $305.1M, representing 100.0% annual top-line growth. It carries a strong balance sheet with $404.7M in net cash as of June 30, 2026.

Market cap
$4.63B
Revenue (TTM)
$397.4M
P/E
155.7x
fwd 69.9x
1Y return
—
S&P 500 16.8%
Avg. target
$129.00
31.5% vs last close

Bull case

  • Revenue grew at a 2-year CAGR of 106.2% between FY2023 and FY2025, reaching $305.1M.
  • Gross margin steadily widened from 24.1% in FY2023 to 68.3% in FY2025, helping drive positive free cash flow of $15.7M.
  • The balance sheet is well capitalized with $404.7M in net cash and a high current ratio of 11.69 as of June 30, 2026.

Bear case

  • Valuation multiples are elevated, including a trailing P/E of 155.7x and forward P/E of 69.9x against peer medians of 24.6x and 17.3x.
  • Analyst consensus expects next fiscal year EPS growth to flatten slightly at -0.7% to $1.49.
  • Short interest stands at 10.8% of float, reflecting caution among some market participants.

What BillionToOne does

BillionToOne, Inc., incorporated in 2016 and headquartered in Menlo Park, California, is a precision diagnostics company that quantifies biology to create molecular diagnostics. It provides a molecular counting platform designed to detect and measure DNA molecules at the single-count level to help enhance disease detection. Its product offerings include UNITY Complete, a non-invasive prenatal screen assessing fetal risk for aneuploidies, recessive conditions, and fetal antigens from maternal blood draws. For oncology, it offers Northstar Select, a liquid biopsy test detecting tumor mutations, and Northstar Response, a methylation-based assay that quantifies cancer levels to monitor patient therapy response without requiring a tissue biopsy.

Growth and profitability

Revenue expanded rapidly from $71.7M in FY2023 to $152.6M in FY2024 and reached $305.1M in FY2025, reflecting a 2-year revenue CAGR of 106.2%. Gross margin improved from 24.1% in FY2023 to 53.0% in FY2024 and 68.3% in FY2025. Operating margin turned positive to 5.3% in FY2025, up from -96.9% in FY2023. Net income shifted from -$82.7M in FY2023 to $7.5M in FY2025, generating FY2025 EPS of $1.06. Over the trailing twelve months ending June 30, 2026, revenue stood at $397.4M with an operating margin of 5.0% and profit margin of 8.3%. Quarterly revenue growth was 64.4% year-over-year.

BLLN income statement →

Balance sheet and cash flow

As of June 30, 2026, BillionToOne held $548.6M in cash and short-term investments against $143.9M in total debt, resulting in net cash of $404.7M. The company maintains solid liquidity with a current ratio of 11.69 and a debt-to-equity ratio of 0.27 on shareholders' equity of $536.8M. Operating cash flow improved from -$53.7M in FY2023 to $24.6M in FY2025, supporting free cash flow of $15.7M after capital expenditures of $8.9M.

BLLN balance sheet →

Valuation and performance

At a last close of $98.12, BillionToOne trades at a market cap of $4.63B and enterprise value of $4.99B. Its trailing P/E of 155.7x and forward P/E of 69.9x stand well above the median of its US-listed Healthcare peers at 24.6x and 17.3x, respectively. The company's price-to-sales ratio is 11.7x compared to the peer median of 4.1x, and its EV/EBITDA is 99.3x versus the peer median of 12.0x. Year-to-date, BLLN shares have gained 19.9%, compared to a 1-year return of 16.8% for SPY.

BLLN key metrics →

What analysts expect

Wall Street coverage includes 5 Strong Buy, 2 Buy, and 1 Hold ratings, with 0 Sell or Strong Sell ratings. The mean price target is $129.00, representing a 31.5% premium to the last close of $98.12. For the fiscal year ending December 31, 2026, consensus estimates project revenue of $454.8M and EPS of $1.50, implying 186.1% EPS growth. BillionToOne has beat EPS estimates in 2 of the last 4 quarters, and its next earnings report date is November 4, 2026.

BLLN forecast and price target →

Key risks and what to watch

  • Quarterly revenue growth moderated to 64.4% year-over-year in the latest quarter from 100.0% in FY2025.
  • Trailing twelve-month operating margin is 5.0%, trailing the US-listed Healthcare median of 14.0%.
  • The company beat EPS estimates in only 2 of the last 4 quarters, introducing potential quarterly volatility.

AI-generated research summary. Written with AI from Quotelinks data as of October 16, 2026 and checked so every figure matches that data. For information only, not investment advice. Disclaimer

About this BLLN AI stock analysis

This page is an AI-written research summary of BillionToOne, Inc. (BLLN). The text was generated on October 30, 2026 from Quotelinks data as of October 16, 2026 (company profile, annual results, latest balance sheet, valuation, price performance and analyst estimates). An automatic check rejects any draft that contains a figure not found in that data. It is not investment advice; verify figures on the linked tabs before making decisions.

Related: BLLN income statement, BLLN balance sheet, BLLN key metrics, BLLN analyst forecast, BLLN chart. See the BLLN stock overview for the latest quote and news.

BLLN AI stock analysis FAQ

Does BillionToOne pay a dividend?

No, BillionToOne does not pay a dividend. The company directs its capital toward business expansion and research, allocating $49.4M to R&D in FY2025.

What products generate revenue for BillionToOne?

BillionToOne offers molecular diagnostics built on its molecular counting platform. Key products include the UNITY Complete prenatal screen, the Northstar Select liquid biopsy test, and the Northstar Response methylation-based assay.

What is the balance sheet status of BillionToOne?

As of June 30, 2026, BillionToOne held $548.6M in cash and short-term investments alongside $143.9M in total debt, yielding net cash of $404.7M and a current ratio of 11.69.

What is the consensus analyst target price for BLLN?

The mean analyst price target is $129.00, which sits 31.5% above the stock's last close of $98.12 on October 16, 2026.

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