Alkermes plc (ALKS) AI Stock Analysis

NASDAQ: ALKSAI research summary: business, growth, valuation, analysts, bull and bear case.

ALKS AI stock analysis summary

AI Research

Alkermes plc is a biopharmaceutical company focused on treatments for central nervous system disorders and oncology. Over the trailing twelve months, the company generated $1.67B in revenue with an operating margin of 15.5%. In FY2025, operating cash flow reached $520.8M alongside free cash flow of $480.3M.

Market cap
$6.92B
Revenue (TTM)
$1.67B
P/E
108.5x
fwd 133.3x
1Y return
33.8%
S&P 500 16.8%
Avg. target
$56.21
36.4% vs last close

Bull case

  • Alkermes generated $480.3M in free cash flow and $520.8M in operating cash flow in FY2025.
  • Quarterly revenue grew 27.0% year-over-year in the latest quarter ending June 30, 2026.
  • Consensus estimates project FY2027 revenue to grow 6.6% to $1.94B with EPS expanding 41.8% to $1.81.

Bear case

  • Full-year revenue declined in consecutive years, dropping 6.4% in FY2024 and 5.2% in FY2025.
  • The stock trades at a forward P/E of 133.3x, substantially higher than the US-listed Healthcare median of 17.3x.
  • Quarterly earnings fell 99.4% year-over-year in the quarter ended June 30, 2026.

What Alkermes does

Alkermes plc is a biopharmaceutical company headquartered in Dublin, Ireland, that researches, develops, and commercializes pharmaceutical products addressing unmet medical needs. Its commercial portfolio and pipeline span schizophrenia, bipolar I disorder, alcohol and opioid dependence, and multiple sclerosis. Key commercial products include ARISTADA, a long-acting treatment for schizophrenia, and VIVITROL, which helps prevent alcohol and opioid dependence. The company also developed formulations such as INVEGA SUSTENNA/XEPLION and INVEGA TRINZA/TREVICTA for schizophrenia management through collaborations with partners like Janssen Pharmaceutica. Additional pipeline candidates include LYBALVI for schizophrenia and bipolar I disorder, and nemvaleukin alfa for oncology.

Growth and profitability

Alkermes posted a 5-year revenue CAGR of 7.3% from FY2020 through FY2025. Annual revenue grew 49.6% in FY2023 to $1.66B before contracting 6.4% in FY2024 to $1.56B and falling 5.2% in FY2025 to $1.48B. Gross margin expanded to 86.7% in FY2025 from 84.2% in FY2024, while net margin fell to 16.4% with net income of $241.7M. For the latest quarter ending June 30, 2026, quarterly revenue grew 27.0% year-over-year, while quarterly earnings declined 99.4%. R&D expense increased to $324.0M in FY2025 compared to $245.3M in FY2024.

ALKS income statement →

Balance sheet and cash flow

As of June 30, 2026, Alkermes held $656.6M in cash and short-term investments against total debt of $1.57B, resulting in net debt of $916.0M. The company maintains a current ratio of 2.30 and a debt-to-equity ratio of 0.87 on shareholders' equity of $1.81B. During FY2025, capital expenditures totaled $40.4M and the company used $31.0M for share buybacks. Five-year share count change was 3.0%.

ALKS balance sheet →

Valuation and performance

Alkermes trades at a trailing P/E of 108.5x and a forward P/E of 133.3x, both well above the median of its US-listed Healthcare peers of 24.6x and 17.3x, respectively. Its price-to-sales multiple of 4.1x matches the peer median of 4.1x, while its EV/EBITDA of 36.6x exceeds the peer median of 12.0x. Over the past year, the stock returned 33.8%, outperforming the S&P 500 (SPY) return of 16.8%, but its 5-year return of 30.2% trails the index return of 83.0%.

ALKS key metrics →

What analysts expect

Wall Street coverage includes 11 Strong Buy, 3 Buy, 4 Hold, and 1 Sell ratings. The mean price target is $56.21, representing a potential upside of 36.4% over the last close of $41.22. For the fiscal year ending December 31, 2026, consensus estimates project EPS of $1.27, representing a decline of 39.2%, on revenue of $1.82B. Alkermes beat EPS estimates in 3 of the last 4 quarters, with its next earnings date scheduled for October 27, 2026.

ALKS forecast and price target →

Key risks and what to watch

  • Short interest stands at 14.7% of float, reflecting substantial negative sentiment.
  • The company carries net debt of $916.0M, with total debt of $1.57B exceeding cash reserves of $656.6M.
  • Current fiscal year EPS is projected to decline 39.2% to $1.27 from previous levels.

AI-generated research summary. Written with AI from Quotelinks data as of October 16, 2026 and checked so every figure matches that data. For information only, not investment advice. Disclaimer

About this ALKS AI stock analysis

This page is an AI-written research summary of Alkermes plc (ALKS). The text was generated on October 30, 2026 from Quotelinks data as of October 16, 2026 (company profile, annual results, latest balance sheet, valuation, price performance and analyst estimates). An automatic check rejects any draft that contains a figure not found in that data. It is not investment advice; verify figures on the linked tabs before making decisions.

Related: ALKS income statement, ALKS balance sheet, ALKS key metrics, ALKS analyst forecast, ALKS chart. See the ALKS stock overview for the latest quote and news.

ALKS AI stock analysis FAQ

What products does Alkermes commercialize?

The company's commercial and development portfolio includes ARISTADA for schizophrenia, VIVITROL for alcohol and opioid dependence, LYBALVI for schizophrenia and bipolar I disorder, and partner products such as INVEGA SUSTENNA/XEPLION.

Does Alkermes pay a dividend?

Alkermes does not currently pay a dividend, prioritizing cash flow for research and development, capital expenditures of $40.4M in FY2025, and share buybacks of $31.0M.

What is the consensus analyst price target for ALKS?

The mean analyst price target is $56.21, which sits 36.4% above the last closing price of $41.22.

When does Alkermes report its next quarterly earnings?

The company is scheduled to report its next earnings on October 27, 2026.

More Healthcare AI stock analysis