ADC Therapeutics SA (ADCT) AI Stock Analysis
ADCT AI stock analysis summary
AI ResearchADC Therapeutics SA is a commercial and clinical-stage biotechnology firm developing antibody drug conjugates for hematological cancers and solid tumors. The company generated $81.4M in FY2025 revenue but continues to operate at a deficit, posting a net loss of -$142.6M. With a market cap of $178.7M and net debt of $198.0M, cash consumption remains a central factor.
- Market cap
- $178.7M
- Revenue (TTM)
- $79.6M
- P/E
- —
- 1Y return
- -66.1% S&P 500 16.8%
- Avg. target
- $3.33 138.1% vs last close
Bull case
- ZYNLONTA and pipeline assets are expanding in clinical trials, supporting projected FY2027 revenue growth of 25.3% to $100.9M.
- The company maintains solid short-term liquidity with a current ratio of 3.03 and $219.1M in cash and short-term investments as of June 30, 2026.
- Wall Street analysts hold a mean price target of $3.33, representing 138.1% upside from the last close of $1.40.
Bear case
- Operating cash outflows reached -$141.2M and free cash flow was -$141.4M in FY2025, requiring continuous capital to fund operations.
- The balance sheet carries $417.1M in total debt and negative shareholders' equity of -$228.2M as of June 30, 2026.
- Existing shareholders have experienced dilution, with the share count increasing by 102.9% over five years.
What ADC Therapeutics does
ADC Therapeutics SA is a biotechnology company developing antibody drug conjugates (ADCs) to treat hematological malignancies and solid tumors. Its key product, ZYNLONTA, is evaluated in Phase II trials for relapsed or refractory diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma, Phase III trials with rituximab for second-line transplant-ineligible DLBCL, and Phase I trials for non-Hodgkin lymphoma. The pipeline includes camidanlumab tesirine in Phase II trials for Hodgkin lymphoma, ADCT-602 in Phase Ia for acute lymphoblastic leukemia, and earlier candidates ADCT-601, ADCT-701, and ADCT-901. The company partners with Genmab A/S, Bergenbio AS, Synaffix B.V., Mitsubishi Tanabe Pharma, Overland Pharmaceuticals, and MedImmune.
Growth and profitability
Annual revenue reached $81.4M in FY2025, up 14.9% from $70.8M in FY2024, following a 66.9% decrease in FY2023 from a peak of $209.9M in FY2022. Gross margin remained high at 90.6% in FY2025, compared to 91.6% in FY2024 and 98.4% in FY2022. However, heavy development costs led to an operating margin of -133.2% and a net loss of -$142.6M in FY2025. R&D expenses were $104.0M in FY2025. Over the trailing twelve months ended June 30, 2026, revenue stood at $79.6M with an operating margin of -118.1% and diluted EPS of -$0.60. For the quarter ended June 30, 2026, revenue increased 2.2% year-over-year.
Balance sheet and cash flow
As of June 30, 2026, ADC Therapeutics held $219.1M in cash and short-term investments against $417.1M in total debt, resulting in net debt of $198.0M. Shareholders' equity was -$228.2M on total assets of $279.4M, with a current ratio of 3.03. The company burned -$141.2M in operating cash flow and recorded free cash flow of -$141.4M in FY2025. Capital expenditures totaled $264,000 in FY2025. Financing activities have expanded the share count, which increased 102.9% over five years.
Valuation and performance
ADCT trades at a price-to-sales ratio of 2.2x and an EV-to-revenue multiple of 0.8x based on an enterprise value of $65.7M and a market capitalization of $178.7M. This represents a discount to the median of its US-listed Healthcare peers, which carries a price-to-sales multiple of 4.1x. Over the past year, ADCT shares declined 66.1%, while the S&P 500 (SPY) gained 16.8%. Over a five-year period, the stock fell 94.5% compared to an 83.0% gain for the benchmark.
What analysts expect
Wall Street coverage consists of 3 Strong Buy ratings, 0 Buy ratings, and 2 Hold ratings. The mean price target is $3.33, implying an upside of 138.1% above the last closing price of $1.40. For the current fiscal year ending December 31, 2026, analysts expect revenue of $80.6M and EPS of -$0.75. For FY2027, 4 analysts estimate revenue of $100.9M and EPS of -$0.68. The company has beat EPS estimates in 3 of the last 4 quarters, and its next earnings date is November 9, 2026.
Key risks and what to watch
- The company recorded a net loss of -$142.6M in FY2025 and an ROE of -705.5% over the trailing twelve months, reflecting sustained unprofitability.
- Stock volatility is high with a beta of 1.86 and a 1-year share price return of -66.1%.
- Net debt stands at $198.0M alongside negative shareholders' equity of -$228.2M, creating balance sheet pressure if operational cash burn persists.
AI-generated research summary. Written with AI from Quotelinks data as of October 16, 2026 and checked so every figure matches that data. For information only, not investment advice. Disclaimer
About this ADCT AI stock analysis
This page is an AI-written research summary of ADC Therapeutics SA (ADCT). The text was generated on October 30, 2026 from Quotelinks data as of October 16, 2026 (company profile, annual results, latest balance sheet, valuation, price performance and analyst estimates). An automatic check rejects any draft that contains a figure not found in that data. It is not investment advice; verify figures on the linked tabs before making decisions.
Related: ADCT income statement, ADCT balance sheet, ADCT key metrics, ADCT analyst forecast, ADCT chart. See the ADCT stock overview for the latest quote and news.
ADCT AI stock analysis FAQ
What is ADC Therapeutics' primary drug?
Its lead product is ZYNLONTA, an antibody drug conjugate in Phase II and Phase III trials for diffuse large B-cell lymphoma and other hematological indications.
Is ADC Therapeutics profitable?
No, the company posted a net loss of -$142.6M in FY2025 and an operating margin of -118.1% for the trailing twelve months ended June 30, 2026.
How much cash and debt does ADCT have?
As of June 30, 2026, ADC Therapeutics had $219.1M in cash and short-term investments, $417.1M in total debt, and net debt of $198.0M.
Does ADC Therapeutics pay a dividend?
No, ADC Therapeutics does not pay a dividend, as it directs capital toward research and clinical development.