Adagene Inc. (ADAG) AI Stock Analysis
ADAG AI stock analysis summary
AI ResearchAdagene Inc. (ADAG) is a clinical-stage biopharmaceutical company developing monoclonal antibody cancer therapies. Over the trailing twelve months, the company generated $9.3M in revenue while recording an operating margin of -1023.9% and a net loss per share of -$0.38. As of June 30, 2026, it holds a strong liquidity position with $121.8M in net cash.
- Market cap
- $138.3M
- Revenue (TTM)
- $9.3M
- P/E
- —
- 1Y return
- 15.7% S&P 500 16.8%
- Avg. target
- $9.91 381.0% vs last close
Bull case
- Adagene maintains a solid cash buffer of $127.9M against just $6.1M in total debt as of June 30, 2026.
- The consensus analyst price target of $9.91 implies an upside of 381.0% over the last close of $2.06.
- Annual net losses narrowed from -$80.0M in FY2022 to -$17.6M in FY2025 as operating cash burn dropped to -$15.7M.
Bear case
- Full-year revenue dropped as low as $103,204 in FY2024, highlighting extreme top-line volatility for this clinical-stage model.
- Operating margin over the trailing twelve months was -1023.9%, reflecting ongoing high costs relative to commercial revenue.
- Over the last five years, shares declined 82.4% while the S&P 500 delivered an 83.0% return.
What Adagene does
Adagene Inc. is a clinical-stage biopharmaceutical company headquartered in Suzhou, China, focused on the research, development, and production of monoclonal antibody drugs for cancer treatment. Founded in 2011, the company employs 128 people and utilizes proprietary research platforms and strategic collaborations to advance its oncology pipeline. Its product candidates include ADG106, an agonistic anti-CD137 monoclonal antibody in Phase 1b/2 trials for advanced solid tumors and non-Hodgkin's lymphoma. It is also testing anti-CTLA-4 candidates ADG126 and ADG116 in Phase 1 trials, anti-PD-L1 candidate ADG104 in Phase 2 trials, and anti-CSF-1R candidate ADG125 in Phase 1 development.
Growth and profitability
Adagene's revenue has fluctuated significantly, posting $10.2M in FY2021, $9.3M in FY2022, and $18.1M in FY2023, before plunging to $103,204 in FY2024. In FY2025, revenue rebounded by 7332.8% to $7.7M, supported by a 100.0% gross margin. Operating margins have remained deeply negative, improving from -711.2% in FY2021 to -279.5% in FY2025 as research and development expenses declined from $68.1M to $22.0M. Net income improved from a loss of -$73.2M in FY2021 to -$17.6M in FY2025. Over the trailing twelve months ended June 30, 2026, revenue stood at $9.3M with quarterly revenue growth of 7332.8% year-over-year, alongside a profit margin of -220.8%.
Balance sheet and cash flow
As of June 30, 2026, Adagene held $127.9M in cash and short-term investments against $6.1M in total debt, resulting in a net cash balance of $121.8M. Liquidity is supported by a current ratio of 5.02 and a low debt-to-equity ratio of 0.06 on shareholders' equity of $106.0M. Free cash flow for FY2025 was -$15.7M, reflecting a reduced cash burn compared to -$45.9M in FY2021. Capital expenditures for FY2025 totaled $17,053, and the company's share count decreased 17.0% over five years.
Valuation and performance
Adagene trades at an enterprise value of $76.3M and a market capitalization of $138.3M. Its price-to-sales ratio stands at 14.9x, compared to 4.1x for the median of its US-listed Healthcare peers. The company's EV/EBITDA multiple is 1.1x, below the peer group median of 12.0x, while price-to-book is 2.2x. Over the past year, ADAG gained 15.7%, trailing the S&P 500 (SPY) return of 16.8%. Over a five-year span, the stock fell 82.4%, compared to an 83.0% gain for the S&P 500. Shares closed at $2.06 on October 16, 2026, which is 39.2% below their 200-day average.
What analysts expect
Wall Street coverage consists of 6 Strong Buy ratings, with no Buy, Hold, Sell, or Strong Sell ratings. The mean price target of $9.91 sits 381.0% above the last close of $2.06. For the fiscal year ending December 31, 2026, consensus estimates project revenue of $2.0M and EPS of -$0.51. For the following fiscal year, 5 analysts project revenue to expand 129.6% to $4.5M with an estimated EPS of -$0.59. The company has beaten EPS expectations in 3 of the last 4 quarters.
Key risks and what to watch
- Revenue for FY2026 is projected to fall to $2.0M from $7.7M in FY2025, prolonging unprofitable operations.
- Free cash flow has been consistently negative, registering at -$15.7M in FY2025.
- The stock traded 39.2% below its 200-day average as of October 16, 2026, pointing to prolonged downward price momentum.
AI-generated research summary. Written with AI from Quotelinks data as of October 16, 2026 and checked so every figure matches that data. For information only, not investment advice. Disclaimer
About this ADAG AI stock analysis
This page is an AI-written research summary of Adagene Inc. (ADAG). The text was generated on October 30, 2026 from Quotelinks data as of October 16, 2026 (company profile, annual results, latest balance sheet, valuation, price performance and analyst estimates). An automatic check rejects any draft that contains a figure not found in that data. It is not investment advice; verify figures on the linked tabs before making decisions.
Related: ADAG income statement, ADAG balance sheet, ADAG key metrics, ADAG analyst forecast, ADAG chart. See the ADAG stock overview for the latest quote and news.
ADAG AI stock analysis FAQ
What is Adagene's core product pipeline?
Adagene is developing several clinical-stage oncology candidates, including ADG106 in Phase 1b/2 trials, ADG104 in Phase 2 development, and ADG126, ADG116, and ADG125 in Phase 1 clinical trials.
Does Adagene have debt?
As of June 30, 2026, Adagene held $6.1M in total debt against $127.9M in cash and short-term investments, giving it net cash of $121.8M and a debt-to-equity ratio of 0.06.
What do analysts forecast for Adagene's revenue and earnings?
For FY2026, analysts estimate revenue of $2.0M and EPS of -$0.51. For the following fiscal year, estimates project revenue of $4.5M and an EPS of -$0.59.
Does Adagene pay a dividend?
Adagene does not pay a dividend, as it directs capital toward funding clinical trials and operations.